(R)-(+)-N-Boc-3-Pyrrolidinol: Everyday Details and Real-world Importance

What Sets (R)-(+)-N-Boc-3-Pyrrolidinol Apart

Some chemicals look complicated at first glance, but (R)-(+)-N-Boc-3-Pyrrolidinol actually falls in line with a lot of the hands-on compounds used in labs and industry. With its chemical formula C9H17NO3, (R)-(+)-N-Boc-3-Pyrrolidinol shows up as a solid, usually looking like white to off-white flakes or crystalline powder. Anyone who’s ever handled flaked or powdered chemicals knows the benefits: less dust, accurate measurements, easy transfers, straightforward storage. Density runs around 1.1 g/cm³, so a container never feels particularly heavy per volume, and it mixes or blends with solvents without surprising reactions or caking.

The Structure Behind the Name

The structure gives the game away on how (R)-(+)-N-Boc-3-Pyrrolidinol behaves. This compound carries a pyrrolidine ring – that’s a five-membered ring with one nitrogen thrown into the mix – plus a Boc protecting group and a hydroxy functional group at the third carbon. That mix makes the compound quite handy as an intermediate in chiral chemistry, where keeping stereochemistry straight influences both cost and success rate down the line. The R-enantiomer brings added specificity. Not all reactions need it, but in pharmaceuticals and specialty synthesis, it’s essential for targeted outcomes.

Specifications and Product Uses

(R)-(+)-N-Boc-3-Pyrrolidinol typically enters the ring as a raw material or building block. It features a melting point between 74 to 77°C; that window fits well for labs where managing phase at room temperature matters. Purity usually stands at 98% or above, which lines up with the needs of high-caliber research, pharma, and fine chemical development. Folks in chemistry or material sciences know these specs let researchers and operators trust the results of their reactions—side impurities often spell project delays or costly repeat work.

Forms and Physical Characteristics

Choices in physical form help folks match the compound to their process. Powder suits weighing small quantities, while flakes help prevent static cling and loss. Pearl or bead shapes don’t turn up much for this material, given the intermediate’s niche roles. Only rarely does it appear as a solution; the solid and crystalline format stays preferred for bulk or shelf stability. It takes up little space, ships safely when packaged well, and transitions into almost any solution or reaction that a pyrrolidine-based intermediate must enter.

Molecular and Chemical Properties

The molecular weight clocks in at around 187.24 g/mol. The main functional groups mean it dissolves without fuss in polar organic solvents. It stays stable under normal storage, so long as the bottle avoids high humidity, heat, or acids that would strip away the Boc group. Most who work with it have little trouble matching it to planned reaction schemes—whether that means deprotection, ring expansions, or amide coupling. These features open doors for synthetic chemists, giving options for custom, stepwise builds and complex, single-pot reactions alike.

HS Code and Safety Details

Anyone moving (R)-(+)-N-Boc-3-Pyrrolidinol across borders relies on its Harmonized System Code for quick processing; most suppliers attach HS Code 293399 as the identifier, fitting the “heterocyclic compounds with nitrogen.” On the safety front, this chemical avoids many of the nightmare scenarios that pop up with harsh reagents or caustic materials. The hazards come more from general handling—avoid contact with eyes, gloves are standard, and like with most lab solids, keep dust out of the air. Not to be confused with friendly household products, but not among the most harmful or acutely toxic materials by comparison.

The Role as a Raw Material

Folks in industry and pharma know that (R)-(+)-N-Boc-3-Pyrrolidinol acts as a steady, unglamorous workhorse: a chiral source, a backbone for other intermediates, and a stepping stone in custom synthesis. Its N-Boc protection allows users to strip it off when needed, letting the pyrrolidinol function shine in downstream chemistry. In drug development, chiral purity and reliable raw materials determine both results and safety—a point that’s never theoretical when human health rides on it. Good sources always back up their labels with evidence: lots, purity grades, and certificates.

Challenges and Paths Forward

Safe storage, clean handling, clear labeling—all these prevent headaches in every lab. But risks show up when supply chains break down or records get sloppy. The fact that (R)-(+)-N-Boc-3-Pyrrolidinol isn’t wildly hazardous doesn’t mean safety slips into the background. Mishaps, mix-ups, or degraded stocks slow down work or threaten outcomes. Adding extra training, supporting documentation, and real-time stock checks builds not just safety, but long-term reliability. Honest product details, backed by traceable origins and clear certifications, close the gap between theory and practice and build trust between buyers, sellers, and end users.