Ethyl Piperidine-3-Carboxylate carries real value in chemical synthesis, often finding its way into research labs and manufacturing plants where the backbone of organic chemistry matters. At its core, this compound features a piperidine ring, a structure frequently used in pharmaceutical raw materials. The ethyl ester group tied to the piperidine ring at the 3-position lets it serve as a flexible building block. Its chemical formula is C8H15NO2. Most chemists know it for supporting the development of complex molecules in both R&D and industrial applications. The compound carries HS Code 2933399090, placing it among nitrogen-function organic compounds during trade or import-export activities.
Take the bottle off the shelf and you'll notice Ethyl Piperidine-3-Carboxylate sitting as a clear to slightly yellowish liquid. Under standard laboratory conditions, the liquid doesn’t form large crystals, and you won’t see flakes or powder like with some raw materials. Some batches might show the substance in a buttery solid state, but liquid remains the dominant form at room temperature. The molecular weight clocks in at 157.21 g/mol. Its density hovers around 1.05 g/cm³, giving it a slight heft compared to water. This density makes the material easy to handle for accurate weighing and mixing in the lab. Melting point sits far below ambient temperatures, so storing it as a liquid becomes the norm. The moderate boiling point, sitting above 200°C, lets you heat the compound without immediate loss to evaporation, which proves handy for certain synthesis reactions.
Chemically, Ethyl Piperidine-3-Carboxylate exhibits classic ester reactivity. The carboxylate piece reacts readily in both basic and acidic conditions, giving chemists leeway to make amides, acids, or engage in transesterification. In storage, moisture should be kept out. Contact with water brings slow hydrolysis and product loss, and regular exposure to air can lead to slow degradation. The liquid form isn’t classified as highly volatile, but a tight cap and a cool, dry place do wonders for shelf life. Its odor might come across as faint and slightly amine-like, reminding experienced hands to work under a fume hood.
Synthetic chemists depend on Ethyl Piperidine-3-Carboxylate as a critical raw material, especially in pharmaceutical synthesis. Its role as an intermediate gives it value for producing active pharmaceutical ingredients (APIs) or fine chemicals. The piperidine nucleus sits at the center of many biologically active molecules, so starting with the ethyl ester at the 3-position grants flexibility in adding complexity later. Scale-up procedures from gram labs to pilot production lines typically use the same liquid, negating the need for added solubilizers. Solubility in common organic solvents like ether and ethanol increases its adaptability in multi-step syntheses, keeping costs down and setups straightforward.
Quality specifications make a direct impact. Purity level generally stands at 98% or higher for research and manufacturing. Water content reads low, usually under 0.25%, and color stays almost clear. Specific gravity matches typical density data, and impurities like residual solvents or unreacted starting materials are routinely kept below 0.5%. Many suppliers provide the compound in liter or kilogram bottles, measuring from small-scale pilot runs to large reactors. Whether ordered as a research sample or bulk raw material, lot analysis sheets will track each of these numbers closely.
Hazard information on Ethyl Piperidine-3-Carboxylate deserves attention. Although not flagged as acutely toxic, irritation to the eyes, skin, and respiratory tract occurs if handled carelessly. Gloves, goggles, and lab coats remain the best practice, as with most esters and amines. Safety Data Sheets (SDS) list it as harmful if swallowed and possibly hazardous in higher concentrations or in poorly ventilated spaces. Emergency wash stations and basic containment offer extra peace of mind. Handling procedures advise against pouring down drains, opting for chemical waste disposal because esters can break down in the water system and possibly harm aquatic life.
This compound doesn’t set off red flags on lists like REACH or TSCA, but reviewing local laws before import or bulk purchase is always smart. Since it supports pharmaceutical or advanced material synthesis, both quality and traceability matter for compliance. Containers clearly labeled with hazard pictograms and batch numbers help in tracing product movement through the supply chain. Attention to spill containment and clean-workspace policy keeps both people and the environment out of harm’s way. Consumers of Ethyl Piperidine-3-Carboxylate benefit from knowing that reputable suppliers maintain transparent records and detailed batch reports, supporting accountability that meets the scrutiny of quality auditors.
