Di(Succinimido) Carbonate, often known by chemists under its molecular formula C9H8N2O7, stands out among chemical raw materials for its unique straightforward structure and practical role in organic synthesis. This material takes shape as a crystalline solid, usually available as white to off-white powder, though on occasion it can be spotted as flakes or even small pearls. Its density hovers between 1.5 to 1.6 g/cm³, which places it comfortably among common solid reagents. The HS Code for Di(Succinimido) Carbonate matches up with most import-export databases, typically falling under 29241990, ensuring traceability across borders and regulatory systems. On the shelf, it never quite looks dramatic—just a regular solid by appearance—yet chemical workers know it brings real value in peptide coupling and other synthesis pathways.
At its core, Di(Succinimido) Carbonate integrates two succinimide rings linked by a central carbonate group. The arrangement allows each succinimido group to contribute to reactivity, making this compound an efficient activating agent during chemical reactions. The molecular weight sits at just under 272 grams per mole, providing a good ratio of reactivity to mass, so labs can dose it precisely for small-scale research or large-scale manufacturing. Its melting point tends to fall in the range of 95-98°C. As a solid, it resists most attempts at dissolution in water but will dissolve in many common organic solvents, providing the flexibility labs need to choose the best solution medium—acetonitrile or methylene chloride come to mind from my own experience.
Di(Succinimido) Carbonate usually arrives as a free-flowing powder, though sometimes suppliers provide it as flakes, which sit somewhere between crystalline and granular formats. Pearls and other specialty cuts exist, but for routine lab work, powder offers the easiest measurement and dispersion across a range of processes. The material sits dry and stable at room temperature, keeping its integrity in sealed containers. Once the seal breaks, exposure to the atmosphere calls for quick, professional handling, as prolonged moisture contact encourages breakdown. The powder sometimes clings to gloves or scoops—a reminder to use care and proper technique.
Professionals prize Di(Succinimido) Carbonate for its efficiency in synthesizing peptides, proteins, and sensitive intermediates. The compound’s structure allows for smooth activation of carboxylic acids for coupling steps, resulting in higher yields than many older reagents. Biomedical research, pharmaceutical production, and more specialized segments of organic chemistry routinely make space for this carbonate. Some of the best known procedures for protein modification count on it for clean, reliable bond formation—an advantage when time and material costs add up. This sort of tool, when handled well, helps drive discovery and supports scalability right through to pilot quantities or commercial runs.
On the specification sheet, typical purity exceeds 98%, with negligible impurities, and a slight variation in color from pure white to faint cream. The density, as mentioned above, supports storage and dosing in bulk or small quantities. Laboratories invest in high-quality versions to keep unwanted by-products at bay, which pays off down the line in faster clean-up and more consistent results. As with many organic solids, the dust from Di(Succinimido) Carbonate carries irritation risks for the eyes, skin, and respiratory tract, prompting users to rely on gloves, eye protection, and dust masks. The chemical occupies the “hazardous” category for shipping and storage, so MSDS sheets include safe handling and first aid advice. I’ve seen, firsthand, that the worst trouble comes from unchecked spills or mixing with incompatible materials—keeping the workbench cleaned up and segregated makes a vital difference.
While it doesn’t fall into routine consumer use, Di(Succinimido) Carbonate earns respect for its reactivity and persistence. Spills or dust clouds shouldn’t just be swept or dispersed; proper cleanup minimizes exposure and prevents release into the general environment. Disposal needs careful attention—neutralization or high-temperature incineration, matched with local regulations, keeps both people and systems secure. As a raw material within chemical manufacture, it rarely faces public visibility, but the professionals on the line—chemists, warehouse hands, transport agents—take real steps to protect themselves and the workplace. Training for new users focuses on reaction rates, safe mixing order, and emergency wash stations. In my work, these steps carry weight not just for compliance but for real peace of mind at the end of the day.
New markets and stricter regulations now press for improvement both in safety and sustainability. For suppliers of Di(Succinimido) Carbonate, that means rigorous process controls, better labeling, and clear transport documents. For end users, smarter storage—humidity monitoring, airtight seals, rotation practices, and timely inventory reviews—reduce mishaps and waste, saving not only money but also time. Calls for greener synthesis routes push innovation both at the bench and among producers, with alternatives like recyclable solvents and in-situ activation methods rising in priority. In my professional path, adopting such standards has streamlined operations and improved safety outcomes, though it requires teamwork, retraining, and consistent leadership from the top down.
