(5-Bromothiophen-2-Yl)-Phenylmethanone draws some attention across labs and manufacturing floors with its combination of aromatic character and strategic halogenation. Here, one side of the molecule features a phenylketone backbone, while the other leans on a thiophene ring, brominated right at the five position. Together, these elements give the compound not just its name, but its specific, often desirable set of chemical and physical traits.
Physical form gives away a lot about what to expect during handling and storage. In the bottle, this substance often settles as off-white to light brown flakes or crystalline powder, a nod to its organic origins and structure. Density falls close to the typical values for aromatic ketones, with a range generally clustering around 1.5 grams per cubic centimeter. Solubility always depends on the solvent, but it tends to dissolve well in common organic solvents like dichloromethane, chloroform, or ethanol, stubbornly refusing to mix with water thanks to its non-polar profile. Melting point sits near 90-110°C, so it stays solid at room temperature, though warmth and environmental control do matter during processing and shipping. Handling powder means dealing with particulate dust, which always carries some risk for inhalation; using pearls or flakes, on the other hand, can limit that problem. Some batches ship as larger crystalline fragments or even compressed solid, making them easier to weigh or transfer.
Molecular structure tends to drive both application and regulatory obligations. The formula, C11H7BrOS, illustrates a backbone of hydrocarbon and an active halogen plus sulfur, giving the molecule its distinct reactivity and influence in synthesis. The ketone functionality, nestled between thiophene and phenyl, serves as a versatile handle for further chemical modification in organic chemistry labs and in scale-up facilities. The three-ring arrangement wires in some rigidity and aromaticity, while bromine adds electronegativity, impacting both synthetic possibilities and required handling precautions. That bromine isn’t just for show: it changes the way the molecule reacts with bases or nucleophiles, and often features in the design of pharmaceuticals or advanced materials.
Product documentation pays close attention to purity—reliable lots run above 97% by standard chromatographic techniques, with low moisture content and verified lack of heavy metal contaminants. Producers typically assign the relevant Harmonized System (HS) Code for customs and freight, usually pointing to the class dealing with aromatic organic chemicals, helping customs teams process it as a specialty intermediate rather than a bulk commodity. Material must ship in air-tight, secure packaging to avoid contamination or moisture pickup, as both can compromise downstream chemistry or safety.
Labs and plants come seeking this compound primarily as a raw material or building block in organic synthesis. Whether serving as a precursor for pharmaceuticals, crop protection agents, or advanced polymers, its dual rings of aromaticity plus bromine often open up new reaction pathways not possible with simpler analogs. Raw materials to make it usually include brominated thiophenes and benzoyl halides, meaning production involves skilled organic synthesis with all the expected quality controls. Many chemists like this intermediate for developing new molecular scaffolds, exploring bioactivity, or constructing specialty dyes and pigments.
Nobody in a lab or production setting can afford to ignore the safety memoranda attached to (5-Bromothiophen-2-Yl)-Phenylmethanone. The powder form may give off nuisance dust, which requires local ventilation and personal protective equipment to prevent respiratory or skin exposure. Direct contact sometimes leads to mild irritation, though systemic toxicity remains low unless ingested or handled carelessly. Brominated aromatics earn special scrutiny under hazardous chemical regulations in many countries, sometimes needing storage in locked cabinets and requiring spill control kits nearby. Like all chemical intermediates, labeling stays clear, showing hazard symbols and preventive advice for both acute and chronic exposures. Safe disposal follows local requirements for hazardous wastes, usually avoiding simple landfill or incineration in open environments.
Several real-world processes rely not just on chemical purity but on bulk handling properties. Density helps workers calculate how much fits into a vessel or drum, ensuring process batches run safely and efficiently. Powdered forms sometimes present challenges with clumping or bridging in feeders; larger flakes or compressed pearls can solve some of those issues, making process operation smoother and waste less likely. In solution, concentration in grams per liter gets used both in bench-scale synthesis and pilot-plant operations, with dissolution rates depending on both solvent and grain size of the starting material.
Practical knowledge matters. Staff who handle this compound keep glove protocols tight, as the powder can linger on benchtops and cause accidents by cross-contaminating other materials or exposing unprotected skin. Eye and face protection stay standard, and everyone on the team learns not to underestimate inhalation risks, especially during weighing and blending. In event of a spill, standard absorbents work, with strict prohibition on flushing to drain: the raw compound and its wastes often require certified disposal companies to ensure environmental standards stay met. Product literature typically includes not just generic hazard info but task-specific precautions—a direct application of real-world experience aimed at keeping people and facilities safe.
To address risks, many outfits invest in closed-transfer systems, limiting manual intervention at every step. Upgraded air filtration in workspaces cuts down airborne droplets, and automatic monitors flag environmental out-of-spec events before they escalate. Traceability solutions for batches—right down to the raw chemical input—let buyers and regulatory bodies track product origins, supporting both safety and supply chain transparency. Teams also talk about swapping out or modifying the compound where alternatives exist with lower hazard ratings, a challenge that sometimes lands on the desks of R&D chemists. Beyond compliance, well-communicated safety culture shows up every day, from PPE training to feedback loops that encourage reports of near-misses or potential process upsets. These layers, built from both experience and ongoing study, help keep innovation and safety moving forward, hand in hand.
