4-(6-Methylbenzothiazol-2-Yl)Aniline brings a distinct profile to the world of chemical intermediates. People working in dye synthesis, pharmaceutical research, or material science often rely on its solid structural base. The compound features a benzothiazole ring substituted at the 6-position with a methyl group, which connects at the 2-position to an aniline group. The molecular formula, C14H12N2S, reveals its foundation in organic chemistry—a backbone formed by aromatic rings, a nitrogen atom at the right spot for reactivity, and a sulfur atom that opens more doors for chemical transformation. Molecular weight lands at 240.33 g/mol, putting it in the sweet spot for many bench-scale lab settings and larger industrial applications.
This compound shows up as an off-white to pale yellow solid at room temperature. Sometimes it gathers as fine powder, sometimes flakes or small crystalline chunks, depending on storage and grade. Handling it, you can feel its fine grit, a sign of careful crystallization and drying. It’s not rare to come across pearl-like granules in specialized material grades, providing flexibility in storage and dosing. The density averages around 1.25 g/cm³, which makes it easier to measure out precise quantities in research and manufacturing. The melting point usually settles between 149-153°C, valuable information for those needing to purify or modify the material through controlled heating. It doesn’t dissolve much in water, but various organic solvents—such as methanol, ethanol, or DMSO—break it down for lab work or chemical processing. Solutions of this compound often look clear to slightly yellowish, signaling purity and absence of major contaminants.
4-(6-Methylbenzothiazol-2-Yl)Aniline stands out because of its functional groups. The amine (-NH2) on the aniline segment enables coupling with acids, polymers, or other reactive intermediates. The benzothiazole ring, carrying both nitrogen and sulfur, sits ready for oxidation, N-alkylation, or condensation reactions—already a favorite motif in fluorescent dyes and imaging probes. Each batch comes with specifications built around purity, often above 98%, along with tight controls on moisture and heavy metal content. Raw material sourcing plays a big role in this: only high-grade starting chemicals produce clean, reproducible lots, which is a must for quality-minded manufacturers. Uncompromising fuel for innovation comes from reliable chemistry, and this compound fits the bill when its structure rings true under NMR and mass spectrometry analysis.
Industry packs this substance in several ways to meet handling and application needs. Most producers wrap it up in high-density polyethylene bottles or bags—airtight, moisture-proof, and opaque to prevent light degradation. Different forms like powder, flakes, crystals, or pearls each serve a distinct workflow. Powder and crystal suit analytical labs, providing accurate dosing and rapid dissolution. Flakes and larger pearls reduce airborne dust, simplifying work and improving safety during weighing or dilution. Some customers request tailored solutions—maybe a pre-diluted liquid in N,N-Dimethylformamide (DMF) or a solvent-specific blend—saving time and boosting process safety on the factory floor. Researchers know the value of a consistent, easily handled raw material: a stable supply chain means less time troubleshooting and more progress in developing colorants, optoelectronic materials, or pharmaceutical candidates.
Chemical import and export run smoothly when substances carry a clear Harmonized System (HS) Code. For 4-(6-Methylbenzothiazol-2-Yl)Aniline, that code generally falls under 293499—covering other heterocyclic compounds with nitrogen hetero-atom(s) only. This tagging speeds customs clearance and ensures compliance with regulations around the world. Safety takes center stage for all raw materials, and this compound calls for basic precautions. Dust can irritate skin, eyes, or airways, underscoring the sense in wearing gloves, goggles, and a mask. Prolonged exposure might cause harmful effects, based on what’s known of aniline derivatives and benzothiazole stability. Anyone working with this substance should follow safety data sheets to the letter—store it away from oxidizers, handle in well-ventilated spaces, and avoid direct contact or inhalation. Waste and spills deserve attention: the best practices insist on using chemical waste containers, not simply washing residue down the drain. This attitude doesn’t just protect workers but helps keep environmental impact in check, especially as regulators worldwide raise their expectations for sustainability and chemical safety management.
This compound isn’t just a curiosity—it plays an instrumental role in crafting new molecules and smarter materials. In dyes and pigments, it provides base colors and luminescent properties, sought after in both textiles and high-end electronics. Pharmaceutical researchers look at its structure for leads on anti-microbial and anti-tumor activity: both the benzothiazole and aniline pieces have decades of data proving their biological value. Electronics makers use derivatives as photo-initiators, sensors, or light-emitting molecules in organic LEDs, working toward thinner, brighter screens and more efficient lighting. What ties these uses together? Trust in the physical and molecular properties—there’s no substitute for predictability when scaling from gram to kilogram lots or translating discovery into products. Each new application asks for dependable specifications, with no room for guesswork on purity, solubility, or reactivity.
No chemical comes without risk, and 4-(6-Methylbenzothiazol-2-Yl)Aniline deserves respect. Studies and regulatory documents point out the possible hazards of similar aromatic amines, particularly in workplace exposure. Skin and respiratory tract irritation crop up in most data sheets, so lab workers and production staff keep their PPE ready. Chronic effects haven’t been widely reported, but the structure’s resemblance to regulated benzothiazoles and anilines leads most companies to treat waste and contaminated materials as hazardous. Eyes toward the future, green chemistry can reduce risks by improving synthesis efficiency, reducing unwanted byproducts, and focusing on non-toxic alternatives wherever feasible. Until then, attention on labeling, storage, and proper disposal makes an enormous difference—protecting people and community health with every decision made at the bench, in production, or during transport.
Sustainable solutions don’t spring up overnight, but targeted efforts already show progress. Chemists in industry often search for alternative, less hazardous solvents for both production and use. Analytical advances help spot impurities faster, reducing the load on downstream purification steps and limiting hazardous waste. Automation in weighing and transfer cuts the risk of exposure and dust formation, translating better lab practices into safer factories. Sharing knowledge and partnering with suppliers on origin, purity, and handling closes the loop between researcher, manufacturer, and end-user. As new regulations come online, staying nimble and informed becomes the key to compliance and safety—ensuring chemicals like 4-(6-Methylbenzothiazol-2-Yl)Aniline remain valuable raw materials without ever slipping into old habits that put workers or the environment at risk.
