4-[3-(1-Naphthylamino)Propyl]Morpholine: Description, Properties, and Applications

What is 4-[3-(1-Naphthylamino)Propyl]Morpholine

4-[3-(1-Naphthylamino)Propyl]Morpholine stands out as a synthetic chemical compound crafted through a careful union of a naphthylamino group and a morpholine moiety linked by a three-carbon propyl chain. Unlike more familiar substances, its structure brings some unique features to the table. Workers, researchers, and production engineers see this material in the form of dense, faintly colored flakes, powder, or occasionally as loosely packed pearls. Not all batches look identical because crystallization, particle size, and even ambient moisture can shape the end product. Most product sold will sit as a crystalline solid at room temperature and resists dissolving in water thanks to the stable naphthyl structure. In a typical laboratory or production line, storage requirements hinge on keeping this compound dry and protected from direct light.

Chemical Structure and Formula

A glance at the chemical backbone reveals a morpholine ring, grafted to a propyl chain, which on its opposite terminus connects to a bulky 1-naphthylamino group. The structure ensures a complex interplay of polar and nonpolar features, tallied up in the formula C17H22N2O — that's 17 carbon atoms, 22 hydrogen atoms, 2 nitrogen atoms, and 1 oxygen atom packed into a single molecule. Molar mass clocks in around 270.4 g/mol. That heavy naphthalene core, fused aromatic rings, and the nitrogen bridge give this compound distinct electronic, optical, and solubility features, impacting how it fits into chemical syntheses or end-user applications.

Physical Properties and Specifications

4-[3-(1-Naphthylamino)Propyl]Morpholine generally emerges as solid flakes but occasionally appears granular or as fine powder, subject to processing conditions during manufacture or purification. Purity hovers at or above 98% for specialty applications, but broader industrial batches can dip slightly, especially if minor byproducts from raw materials linger. Testing reveals density figures typically in the range of 1.08 to 1.15 g/cm³ at 20°C, though crystal orientation and compaction play a small role. Most formulations melt at temperatures above 140°C, requiring attention in shipping and storage to prevent caking or melting in transit. This compound doesn't dissolve easily in water, but will break down in some organic solvents — ethanol, chloroform, and acetic acid among them — which helps during formulation, extraction, or waste handling.

HS Code and Regulatory Status

Trade, transport, and use for industrial or research purposes require proper classification. The Harmonized System (HS) Code for products in this category generally falls under 293499 — covering heterocyclic compounds with nitrogen hetero-atoms. Customs agents and safety managers check this identifier for both international tariffs and guidelines on safe handling in transport. Products moving across borders or in bulk need clear paperwork, with documentation covering batch numbers, molecular formula, and origin of raw materials. Countries with strict chemical controls may require end-use certificates or declarations for customs at import, especially when the substance will be used for research or in regulated industries.

Material Handling and Safe Use

Safety with 4-[3-(1-Naphthylamino)Propyl]Morpholine draws from both chemical common sense and the facts found in published toxicology reports. Dust from powders or crystals can irritate the respiratory tract, especially for those working without masks or ventilation. Direct skin contact may cause redness or mild irritation, so most facilities call on gloves and long sleeves when working with the pure substance or during weighing and transferring. Accidental splashes, improbable as they are, call for a thorough rinse of the affected area; eye contact means an immediate water flush and, if discomfort persists, a trip to medical staff. Studies conducted on related morpholine compounds show low acute toxicity, but chronic exposure — like with many aromatic amines — should get avoided. Fume hoods, eye protection, and safe waste containers become routine parts of any operation making, testing, or using this compound. Storage guidelines specify sealed containers, away from oxidizers and strong acids. Any signs of decomposition — color changes, strange odors, clumping — warn experienced handlers to review shelf life and product quality before use.

Molecular and Solution Properties

Solubility profiles matter for chemists designing reactions. The naphthyl ring, coupled with the morpholine nitrogen's moderate polarity, gives this molecule a slight tendency to dissolve in polar organic solvents but little affinity for pure water. In solution, product color may range from pale yellow to off-white depending on batch purity and solvent choice. This behavior impacts both the effectiveness in synthesis routines and cleanup strategies post-reaction. Viscosity and flow properties, particularly for higher concentration solutions, demand careful mixing to avoid crystallization or formation of unwanted gels. Researchers often track UV absorption, using the naphthalene chromophore as a tool for quantifying substance and purity in liquid phase.

Raw Materials and Production Challenges

Producing 4-[3-(1-Naphthylamino)Propyl]Morpholine draws on a reliable source of morpholine, propyl halides, and 1-naphthylamine. Each step in synthesis carries hazards — alkylation, amination, purification — and these reactions need proper temperature control, ventilation, and waste capture. Purity depends on removing starting material residues, which, if left behind, can reduce product quality and change physical properties. Factories must keep a tight rein on source quality, due to risks associated with contaminated or impure raw components, which can result in downstream complications during product application or regulatory compliance checks. Logistics teams keep watch on delivery and anonymity of sources, as all named chemical ingredients, especially aromatic amines and morpholine, have their own safety and storage requirements.

Hazardous, Harmful, and Environmental Aspects

Risk evaluation for 4-[3-(1-Naphthylamino)Propyl]Morpholine focuses on handling and disposal. The compound remains stable under standard lab and plant conditions, but burning or intense heat may create toxic gases — mostly nitrogen oxides and polycyclic aromatic hydrocarbons — so fire safety means more than a simple extinguisher on the wall. Waste must not get dumped down the drain; licensed chemical collectors neutralize and incinerate hazardous remnants following strict local and national rules. For environmental exposure, the danger level reflects both the stubbornness of the naphthyl ring against breakdown and the trace presence of unreacted amines. Treated with respect, the risk to humans and the environment drops, but labs and facilities take regular audits and update MSDS sheets to avoid surprise incidents. Worker training, regular air monitoring, and easy access to safety data matter more than glossy safety slogans in practice.