3.5-Dimethoxybenzoic Acid: Description, Uses, and Safety

What is 3.5-Dimethoxybenzoic Acid?

3.5-Dimethoxybenzoic Acid comes from a group of compounds called benzoic acids. The addition of two methoxy groups onto the aromatic ring *at the 3 and 5 positions* gives it its name and sets it apart from plain benzoic acid. Anyone who works with chemicals in a lab or an industrial setting comes across names like these, and each small change in structure changes its properties and how it behaves. At its core, it has the formula C9H10O4. Its molecular weight clocks in around 182.18 g/mol. Over the years, chemists working in both research and production have used this acid in everything from the making of dyes to drug building blocks and specialty resins.

Physical and Chemical Properties

This acid takes on a solid form at room temperature, sometimes showing up as pale flakes or off-white crystalline powder. Put it in your hand, and you notice a feeling between wax and dry powder, nothing especially greasy or sticky. Its melting point settles somewhere between 180°C and 184°C. Try to dissolve it in water, and you run into a bit of resistance—solubility stays low, but swap over to organic solvents, such as ethanol or ether, and it starts mixing well. Its density lands around 1.3–1.4 g/cm3, which matters any time you need to weigh, pack, ship, or blend it for formulations. The structure—a benzene ring with two methoxy groups (–OCH3) and a carboxylic acid (–COOH)—creates a balance between stability and reactivity. In practice, these features explain why it resists easy breakdown, tolerates moderate heat, and works as a starter chemical in various synthesis projects. From my time handling it in academic labs, I found it tends to clump if moisture is nearby, so good storage pays off.

Main Specifications

Industry specifications often call out an assay above 98%, meaning not much room for impurities. The crystalline form draws the eye during inspection, pointing toward purity, and usually, it comes as neatly separated powder or brittle flakes. Moisture, as measured by Karl Fischer titration or similar methods, tends to lie below 0.5%. Packing varies—many labs keep it in 25kg drums or double-sealed bags inside heavy buckets. These limits ensure both safety and product quality for customers across pharmaceuticals, dyes, and advanced materials. Those who care about tracking need the CAS number: 5618-24-2. This number identifies it worldwide on labels, customs paperwork, and databases. For customs purposes, the HS Code often used is 29182900, under benzoic acid derivatives. Even when working with suppliers far from home, these numbers keep everyone on the same page.

Raw Material Roles and Practical Uses

Many in the chemical world start with 3.5-Dimethoxybenzoic Acid as a foundation for bigger molecules. A solid portion ends up in research labs, attached to experiments on new anti-inflammatory drugs, antibiotics, or dyes. Some processes rely on it for its ability to make new bonds with other aromatic rings, especially in pharmaceutical synthesis. I remember one manufacturing run, where using slightly impure material produced an entirely different dye shade—a reminder that a single missing methoxy group throws off results. Since it stays solid above room temperature and does not pick up water from the air very easily, many companies favor it for precise, high-purity formulations. Blending it into resin systems introduces specific chemical signatures useful for specialty plastics or coatings, where matching color and durability really matter.

Physical Forms: Flakes, Powder, Crystals

Processors shape it into flakes, solid powder, or fine crystals based on intended use. Powder travels well through conveyor lines, makes for easier weighing, and ensures quick mixing. Flakes stack better, avoiding dust, so in large batches, flakes often help minimize spillage. I have stocked jars and barrels packed with off-white crystals, which resist breaking down into dust even with long-term storage, showing an underestimated advantage. If someone uses a liquid or pearl form, it’s usually the acid dissolved in a compatible organic solvent for large-scale processing. Every form comes with tradeoffs: flakes cut down on airborne particles, powder delivers fast reactivity, and crystals signal good handling technique back at the plant. All physical shapes share the underlying property of low volatility—they won’t just float away or turn to gas under normal warehouse conditions.

Density, Storage, and Handling

With a listed density between 1.3 and 1.4 g/cm3, this acid falls toward the denser side for organic solids. Knowing this, teams design packaging and shipping plans that hold up under pressure—a 25kg drum of 3.5-Dimethoxybenzoic Acid weighs about the same as a microwave but with a fraction of the physical size. Keeping the acid in well-sealed containers away from direct light prevents slow degradation and accidental moisture uptake. Safety sheets recommend gloves and goggles for good reason. The fine particles or flakes can irritate skin, nose, or throat with enough exposure, and even modest spills can lead to slippery surfaces. In my early years in chemical plants, I learned firsthand how neglected barrels sometimes clump up, create headaches in production, and waste time breaking them down. Correct storage makes inventory last longer and keeps quality high.

Safety, Health, and Environmental Impact

3.5-Dimethoxybenzoic Acid is not as hazardous as some heavy hitters in the lab like cyanides or strong acids, but it demands respect. Safety data marks it as an irritant rather than a poison. Breathing in a dust cloud can cause coughing or discomfort, and prolonged skin contact leads to redness. If a spill happens, dry cleanup with gloves keeps risks to a minimum. Some regulatory lists require labeling the material as hazardous under certain transport or disposal rules, especially for bulk shipments. In my region, small labs dispose of its waste by diluting and neutralizing with common bases, following local chemical control rules. For big users, professional chemical waste handlers take over, making sure no soil or water contamination happens. At a larger scale, its handling and storage echo the same themes—dry, sealed, clearly labeled, never stored near food or acids that might trigger reactions.

Solutions to Key Issues

Over time, people working with 3.5-Dimethoxybenzoic Acid run into similar trouble spots: clumping from bad storage, dust during transfer, and regulatory confusion from outdated labeling. Upgrading to airtight, lined containers dramatically cuts down on clumping and moisture. Adding local exhaust fans in areas where powder transfers occur slices dust risk and protects workers. Many firms improve training, showing new staff all the trade tricks to minimize contact and keep everything safe but efficient. Relying on updated digital inventory and current MSDS sheets sorts out shipping and labeling headaches, especially wherever customs clearance looms. Larger users benefit from batch tracking and regular audits of storage areas. Not every problem finds a single fix, but a blend of practical habits makes dealing with the acid predictable and keeps it in for the long haul.