3,4-Dihydro-2H-1,4-Benzoxazin-6-ol: Product Description, Properties, and Safety

What is 3,4-Dihydro-2H-1,4-Benzoxazin-6-ol?

3,4-Dihydro-2H-1,4-Benzoxazin-6-ol shows up most often in research labs, chemical industries, and certain high-specification materials applications. This compound, a member of the benzoxazine family, carries the molecular formula C8H9NO2. Each molecule contains an aromatic ring fused with an oxazine ring structure and a hydroxyl group attached at the 6-position, which shapes its reactivity and physical properties. For anyone familiar with organic chemistry, this creates a structure that is both rigid and capable of engaging in interesting hydrogen bonding, which changes how it behaves both in its pure state and as part of bigger chemical systems.

Physical Properties and Appearance

Pure 3,4-Dihydro-2H-1,4-Benzoxazin-6-ol appears in several forms, usually as a crystalline solid or fine powder. The color can range from off-white to pale beige, depending on purity and how the material was synthesized or stored. In a handful of cases, the compound gets processed into small flakes, pearls, or even coarse grains to help with handling or mixing. Some batches melt easily under moderate heat, while others keep a higher melting point, which brings extra thermal stability for people working with aggressive reactions or high-temperature synthesis. Lab experience shows that crystallinity plays a big role in how the compound dissolves or reacts, with clear, well-defined crystals offering better storage and purity control.

Chemical Specifications and Molecular Structure

Industry specifications usually highlight the density, solubility, and purity levels of this material. A typical sample has a density of about 1.28 grams per cubic centimeter, based on data from standard analytical reports. Solubility in water stands as modest, but it dissolves better in alcohols and organic solvents due to the polar aromatic and oxazine groups. The HS Code for this substance often falls within 293499, which covers heterocyclic compounds with oxygen/nitrogen functionality. Anyone working on synthesis pathways notices the unique 1,4-benzoxazine core—a building block for more complex industrial chemicals, polymer precursors, or specialty coatings. With the structural formula C8H9NO2, chemists see these benzoxazine rings as bridging traditional aromatic chemistry and new-age applications in materials science.

Function as Raw Material

3,4-Dihydro-2H-1,4-Benzoxazin-6-ol stands out as a valuable raw material in polymer development, advanced resins, and even in the field of agrochemicals. Most people in technical manufacturing opt for this compound because it delivers both chemical resistance and flexibility, making it a go-to choice for custom synthesis where adjusting physical properties matters. Over several years in the lab, composite engineers or researchers often seek this molecule for experimental purposes, where its ring structure and functional hydroxyl group open a door for bond formation or targeted reactions. Companies looking for cost-efficient but high-quality starting materials factor in not just price, but chemical purity, particle size, and delivery form—flakes, powder, or solid crystal can each make or break a process.

Handling, Safety, and Hazards

No one in the lab treats unfamiliar chemicals lightly, and that mindset applies here. 3,4-Dihydro-2H-1,4-Benzoxazin-6-ol carries moderate hazard potential. Direct contact causes irritation for sensitive skin, eyes, or mucous membranes. Inhalation of powder always presents risk, not just for this compound but for fine particulates in general. Material Safety Data Sheets recommend nitrile gloves and eye protection as a bare minimum, with local exhaust or general ventilation where larger quantities get handled. Fire risk stays low, but heating past decomposition temperatures sees the release of nitrogen oxides and organic vapors that bring secondary risks. Disposal and transport require labeling under chemical regulations, and shipping sticks to the UN and GHS recommendations for potentially hazardous organics. Most labs keep this chemical in dry, tightly sealed containers, out of sunlight, to prevent breakdown or moisture absorption.

Practical Applications and Industry Relevance

Applications keep expanding, especially in specialty polymers and nanomaterials. Composite companies often experiment with this benzoxazine to achieve advanced coatings or heat-resistant finishes. In agricultural research, derivatives of this compound act as building blocks for new bioactive compounds, especially those aimed at sustainable crop protection strategies. Those who work daily with formulation or synthesis see clear value in raw materials with consistent specs—consistent bulk density and granule size reduce headaches during scaling up production or moving to automated systems. The product's use in both large-scale chemical plants and fine chemical development pushes chemists and engineers to fine-tune process safety, cost evaluation, and regulatory compliance.

Addressing Challenges and Responsible Use

Reliable access to high-purity 3,4-Dihydro-2H-1,4-Benzoxazin-6-ol makes a difference in research output and product performance. Sourcing remains one challenge, since regional supply chains sometimes disrupt stock or bring price swings. Laboratories and manufacturing facilities that stress safety culture tend to see fewer incidents related to exposure or accidental handling errors. Educators in university labs hammer home personal protective equipment not just as a formality, but as second nature. Regulatory pressure, both for worker safety and environmental responsibility, means storing and disposing of this substance responsibly keeps everyone in line with local and global standards. Engineers and managers who keep accurate records, provide clear training, and insist on top-tier material integrity put their teams in a better spot, helping avoid both accidents and regulatory problems.