2-Cyano Pyrazine stands out in the field of specialty chemicals, finding a place in various material sciences and intermediate synthesis processes. Chemically, it displays a robust pyrazine ring structure, with a cyano group (-CN) attached to the second position. The molecular formula, C5H3N3, gives it a calculated molecular weight of 105.10 g/mol. Due to its structure, this compound fits naturally in research and manufacturing pipelines seeking novel nitrogen-heterocycle contributions. Authentic samples present a pale yellow, crystalline solid—sometimes observed as flakes or powder, depending on handling and storage conditions. Each form easily highlights the compound's density, which measures close to 1.19 g/cm³ in solid state. These fundamental qualities shape how manufacturers approach storage, transportation, and material compatibility.
Molecularly, 2-Cyano Pyrazine comprises a six-membered aromatic ring where two nitrogen atoms anchor the framework. The addition of the cyano functional group pulls the electron density, shifting reactivity and shaping product outcomes during chemical synthesis. These solid-state forms remain hard and brittle under routine laboratory pressure. Under intense scrutiny, powder or crystalline forms appear nearly moisture-free, providing a pure, uncontaminated surface ideal for further reactions. Working with bulk materials, one often encounters 2-Cyano Pyrazine packed as solid pearls, uniform flakes, or as microcrystalline powder—each chosen to minimize handling loss and support consistent batching. These physical properties have direct implications for process safety and technical purity.
The melting point of 2-Cyano Pyrazine typically measures around 90–93°C, signifying a relatively low-energy phase change compared with higher molecular weight pyrazines. Chemists choose this compound specifically for its ability to dissolve in organic solvents—such as ethanol, acetone, or ethyl acetate—forming clear solutions suitable for analytical or preparative work. Its density supports straightforward calculations for solution preparation, especially for scaling up reactions in pilot or industrial environments. As a raw chemical, its stability under ambient conditions fosters convenient storage, though direct sunlight, excess heat, or moisture introduce unnecessary risk for degradation or hydrolysis. Documentation under HS Code 2933.59 categorizes it as a nitrogen-heterocyclic chemical, carving out a clear slot in both domestic trade and international customs operations. Inventory tracking using this code eases compliance and traceability during audits or transport checks.
In the world of chemical manufacturing, 2-Cyano Pyrazine provides a core building block for pharmaceuticals, agrochemicals, and electronic materials. Researchers value its unique reactivity profile and the controlled introduction of cyano groups during complex multi-step syntheses. In pharmaceutical routes, this molecule acts as a raw material, offering a stepping stone toward more elaborate heterocyclic drugs containing multiple nitrogen atoms. Its predictability and clean conversions provide confidence for chemists designing synthetic routes requiring tightly defined intermediate purity. As a powder or solid crystal, it handles well with common feeding, dosing, and measurement hardware. I have seen process engineers evaluate batches by hand, checking for flow properties and consistency before charging material into reactors—highlighting the need for reproducible physical form between lots. In agrochemical synthesis, technical teams draw on its aromatic nitrogen ring to give herbicides and fungicides strong backbone stability, allowing the final products greater persistence under field conditions.
2-Cyano Pyrazine, though stable, needs practical handling protocols. Contact with skin or eyes causes irritation; inhaling dust brings respiratory discomfort. Good ventilation matters, as does the use of gloves and protective eyewear. Storage in dry, sealed containers, away from direct sunlight or open flames, prevents unwanted decomposition. The compound's moderate toxicity, noted in animal studies, means careful attention to spill cleanup, proper labeling, and adherence to recommended exposure limits. Disposal usually falls under regulated chemical waste streams due to its classification as a hazardous material in several jurisdictions. For safe transport, containers must satisfy IATA and IMDG guidelines, particularly for sea or air freight. I have watched production floor safety teams use clear labeling and double containment for small-volume samples, acknowledging both regulatory and health responsibilities. By observing the correct protocols, manufacturers and laboratories help prevent short- and long-term adverse effects for both operators and the environment.
2-Cyano Pyrazine finds a steady demand from industries that prioritize reliability, chemical purity, and ease of integration within synthesis networks. The straightforward crystalline solid makes it accessible for dispensing, mixing, and quality control. The density and melting point values allow for efficient material movement and conversion in chemical reactors. Industry teams continue to track technical advances that improve purity and yield, aiming to reduce waste and increase throughput for bulk consumers. The robust structure and commercial availability, anchored by clear HS coding, make sourcing predictable and reduce friction during procurement. While the current safety guidelines already set a strong standard, advances in containment and greener handling protocols should keep improving workplace and environmental safety for years to come.
