2-(2-Piperazin-1-Ylethoxy)Ethanol: Description, Structure, and Properties

What is 2-(2-Piperazin-1-Ylethoxy)Ethanol?

2-(2-Piperazin-1-Ylethoxy)Ethanol shows up across chemical projects that require a blend of flexibility and targeted performance. This organic compound carries the molecular formula C8H18N2O2, and each molecule combines the reactive nature of both a piperazine ring and an ethoxyethanol chain. Its physical configuration supports its use as an intermediate in pharmaceuticals, coatings, additives, and other specialty applications, simply because its dual chemical functions—hydroxy and amine groups—let it participate in a wide set of reactions. Some folks in the industry call this molecule a building block for more advanced synthesis, especially in the making of custom polymers or drug molecules.

Molecular Structure and Chemical Formula

The backbone of 2-(2-Piperazin-1-Ylethoxy)Ethanol presents a straightforward chain: a piperazine ring tethers to an ethoxyethanol segment. Each segment brings something to the table. The piperazine ring, with four nitrogen atoms, supports hydrogen-bonding potential and accepts further modification, making it ideal for fine-tuning end products in the lab or on the shop floor. Chemistry staff reach for this molecule thanks to the combination—C8H18N2O2 is more than just a set of atoms; it’s a pair of reactive sites that help boost solubility and reactivity. This chain gives the compound a particular behavior, especially in terms of solubility and stability under different conditions.

Physical Properties

Depending on the manufacturer or storage, 2-(2-Piperazin-1-Ylethoxy)Ethanol appears as a pale solid, often showing flakes, pearls, or powder forms. Some handlers report a crystalline appearance, while others notice the product turning slightly sticky if left in a humid environment—thanks to the hydroxyl group’s tendency to attract water from the air. This compound features a molecular weight of about 174.24 g/mol. The density stands around 1.08 g/cm³, so it doesn’t differ much from many other organic liquid or waxy intermediates sitting on chemical storage shelves. Because of its structural flexibility, it can also turn up in highly pure liquid form at room temperature, depending on how it’s produced and stored.

Material Specifications and Applications

This raw material gets used widely for making specialty chemicals. It often shows up as a starting point in pharmaceutical synthesis, thanks to its dual functional groups enabling multiple reaction routes. Chemical manufacturers may highlight purity levels, moisture content, and particle size in their specs since these properties matter for productivity. Handling material in powder or pearls—easy enough with the right PPE and procedures—lets users control reaction rates and solubility for precise formulations. In my experience, watching for clumping or moisture absorption is just as important as checking specs on a data sheet. It's the difference between a smooth process and an unexpected shutdown.

HS Code and Regulation

Officially, 2-(2-Piperazin-1-Ylethoxy)Ethanol comes under a broader chemical HS Code category in most customs systems. This code helps with global tracking, trade compliance, and meeting regulatory standards. Manufacturers and importers stay on top of paperwork to make sure this compound flows smoothly through supply chains. Beyond trade, country-specific documentation directs how to ship and store it, and staying informed on those rules prevents any downtime or compliance hiccups.

Safe Handling, Hazards, and Environmental Impact

Anyone working with 2-(2-Piperazin-1-Ylethoxy)Ethanol deals with a material that brings some health and safety risks. Its structure lets it absorb into the skin and eyes, so gloves, goggles, and proper ventilation stand as non-negotiables in any lab or plant. I’ve seen accidents where a missed spill or skipped glove turns a routine session into an emergency room visit. This compound qualifies as hazardous under several local and international systems; inhaling dust or fumes, or ingesting residue, comes with clear risks. Disposal always needs attention, as the nitrogen-rich structure can pose environmental threats if released without neutralization. Workers benefit from regular training and clear signage since familiarity often breeds shortcuts.

Improving Chemical Safety and Efficiency

The industry runs smoother by investing in storage containers that keep moisture out and prevent accidental mixing with incompatible chemicals. Automation further boosts safety—limiting direct human exposure during weighing or mixing steps. Lab techs who share best practices and troubleshoot solvent compatibility issues prevent small errors from ballooning into large costs. At the regulatory level, keeping updated Safety Data Sheets on hand and training staff to interpret them guards against routine accidents. From my end, a culture of open reporting—where folks can raise concerns about process changes or new shipments—strengthens both compliance and efficiency.