1-(M-Chlorophenyl)piperazine, also known in some circles as mCPP, fills a unique space in the chemical world. The compound comes with a molecular formula of C10H13ClN2, putting it into a specific class of piperazine derivatives, where its chlorophenyl ring shapes both chemical behavior and user safety concerns. As a white to off-white solid, mCPP shows up in a few familiar forms: flakes pop up in some labs, while powder usually fits bulk shipment better, and crystalline forms support analytical or specialty use. Some facilities receive it in pearl or granulated form for easier handling.
Sliding a microscope over to its structure, 1-(M-Chlorophenyl)piperazine features a six-membered piperazine ring, bonded to a meta-chlorophenyl group. That position of the chlorine atom—meta—matters: it shapes the compound’s reactivity, stability, and how it interacts with other chemicals. Density clocks in around 1.16 g/cm³, but can vary slightly with temperature and purity levels. The melting point reaches about 214-215°C under standard lab conditions. Its solubility in water does not draw headlines, though dissolving in organic solvents goes more smoothly, which changes how labs store and process it.
Many buyers see 1-(M-Chlorophenyl)piperazine as a solid. The compound can also appear as free-flowing flakes or coarse powder. In some research cases, it’s compacted into small pearls for controlled dosing or handled as a technical-grade crystal. Getting the form right matters because dust from powders poses inhalation risks, solid lumps can be harder to blend, and each physical state calls for different storage containers. Its stability at room temperature lowers spoilage risk, but direct sunlight, moisture, and excessive air all push toward faster degradation or contamination.
Raw materials such as 1-(M-Chlorophenyl)piperazine find themselves pulled into several industries. Pharmaceuticals use mCPP as an intermediate, forming a link in the creation of other compounds. Sometimes, research teams use it as a reference standard for analytical work or chemical testing, because that meta-chloro group introduces unique signals on analytical instruments. Other manufacturers keep it on hand as a building block for agricultural chemicals or dyes, riding on the reliability of its chemistry. Improper use or handling crops up, too, so responsible sourcing helps sidestep regulatory turbulence and contamination of supply chains.
Every chemical comes with safety baggage, and 1-(M-Chlorophenyl)piperazine carries weight here as well. The HS Code usually sits under 2933.59, drawing attention at customs for being a potential precursor in pharmaceutical or technical applications. This compound ranks as hazardous: swallowing, inhaling, or just plain skin contact all create opportunities for irritation or worse complications, especially if any residual solvents or byproducts hitch a ride. Always working with gloves and eye protection knocks down risk. Storage in tightly sealed containers, away from open flames and strong oxidizing agents, stands as basic good practice. MSDS reports warn about chronic exposure and recommend local exhaust ventilation where dust or vapors roam the air.
Anyone who’s worked in a busy analytical chemistry lab has probably felt the stress of handling pure, hazardous compounds. That sharp, unfamiliar odor from the container or the worry over a stray flake landing where it shouldn’t: mCPP is no exception. Proper labeling, segregated storage, and routine spill preparedness drills keep staff safe. Manufacturers need reliable purity testing, not just to meet regulations but to ensure downstream users build pharmaceuticals from trustworthy raw materials. Disposal requires attention, too, with chemical waste streams marked and shipped through official channels, avoiding release into regular trash or drains. Over the years, I’ve learned it pays to make the extra checks on paperwork and storage conditions—cutting corners leads to lost inventory and far worse, risky incidents that slow down everyone’s work.
Raising safety in handling 1-(M-Chlorophenyl)piperazine needs a mix of smart planning and constant reminders. Training isn’t just a box-check for regulatory compliance: real, hands-on practice with chemical spills or containment drills builds habits for those busy shifts when mistakes loom. Automated dispensing systems leave less to chance, cutting down on escape of dust or physical contact, and better personal protective equipment keeps up with new information as material safety data improves. Teamwork between suppliers and buyers also lowers surprises: providing full traceability, reliable purity specs, and extra documentation helps others in the supply chain make decisions about storage and disposal. Keeping discussions open along the way means that no one gets blindsided by new hazard declarations or shifts in regulatory attention.
1-(M-Chlorophenyl)piperazine stands as a white or off-white solid, sometimes flake, powder, pearl, or crystalline depending on supply source. Its molecular formula, C10H13ClN2, accounts for a measured density of roughly 1.16 g/cm³, with a relatively high melting point beyond 214°C. Stable in dry, sealed containers away from oxidizers, it deteriorates with moisture or light. Used as a raw material in pharmaceuticals and specialty chemicals, it carries HS Code 2933.59, underlining its status as regulated cargo. Hazard warnings include risk from ingestion, skin and respiratory contact, and environmental disposal. Trained handling, strict inventory controls, and clear documentation keep risks in check, while regular hazard reviews and tightening supply chain transparency set the foundation for safer use in future research and industrial settings.
