1-Benzhydrylpiperazine, commonly known as N-benzhydrylpiperazine, belongs to the family of piperazine-based chemical compounds. Its primary composition includes piperazine linked to a benzhydryl group. The structure offers a foundation for both research and development in chemical, pharmaceutical, and industrial sectors. Chemists frequently encounter this material as a key building block when exploring molecular interactions or creating new compounds for specialized uses. With wide-ranging applicability as a precursor or reagent, this compound plays a critical part in advancing scientific knowledge and product innovation.
Chemically, 1-Benzhydrylpiperazine features a molecular formula of C17H20N2, formed by the joining of a benzhydryl group to the nitrogen atom of a piperazine ring. The structure’s arrangement supports unique molecular recognition and binding properties. The molecule’s backbone generally remains stable across a range of common laboratory conditions, making it manageable for experienced chemists. The molecular weight stands at approximately 252.36 g/mol, and the compound maintains consistent stability in sealed containers, suggesting safe handling practices in controlled environments.
On inspection, 1-Benzhydrylpiperazine usually appears as fine crystals or a powder, often presenting itself as white or off-white solid flakes. Researchers often find the compound easy to manipulate, whether measured in grams or handled in bulk batches. The density of the material sits near 1.12 g/cm³, and it typically retains a dry, free-flowing character. Melting points for samples of this compound fall within the range of 142–146°C, providing a clear indication for purity testing. This crystal or powder dissolves reasonably well in a variety of common solvents such as ethanol or dichloromethane, offering flexibility and versatility for those seeking to incorporate it into new formulations or reactions.
Reliable handling starts with knowing the specific identifiers and regulatory status. The recognized HS Code for 1-Benzhydrylpiperazine falls under 2933.59, which covers heterocyclic compounds with nitrogen hetero-atoms. Consistent CAS reference helps to distinguish this compound from related substances. Laboratories often use spectroscopy, chromatography, or chemical titration to confirm identity and purity, bringing accuracy to the research process. Chemists and procurement professionals consider the compound’s documented specifications—including formula, molar mass, purity percentage, and batch origin—to inform purchase and use. Technical datasheets usually supply details on appearance, melting point, density, and solubility to support regulatory compliance.
Like many organic chemicals, 1-Benzhydrylpiperazine deserves respect and attention during storage and use. Experienced handlers know to keep it sealed in dry, cool, and well-ventilated areas. Prolonged exposure to moisture or direct sunlight can threaten stability or introduce impurities. Users should wear protective gloves, goggles, and suitable clothing since dust or direct contact may cause mild irritation to skin or eyes. Workplace safety sheets list it as harmful if swallowed or inhaled and recommend proper ventilation. Fire-fighting measures call for foam or dry chemical extinguishers. Disposal requires an approach consistent with local chemical safety regulations, as the breakdown products of piperazine derivatives may pose harm to aquatic environments.
Companies and research institutions treat 1-Benzhydrylpiperazine as a versatile raw material. Its unique structure supports medicinal chemistry efforts, especially in synthesizing candidate pharmaceuticals, innovative polymerization processes, and analytical applications. Chromatography scientists rely on its known properties as a reference for separation methods. The compound sometimes serves as an intermediate for antihistamines, anti-inflammatory agents, and other biologically active molecules. With growing demand for targeted drug development, technicians learn to value traceability and quality control checks, ensuring consistency during synthesis. Specific density, melting characteristics, and solubility contribute directly to reproducibility and scale, key concerns for those moving from bench research to commercial operations.
Depending on processing requirements, 1-Benzhydrylpiperazine appears as flakes, powder, crystals, or dissolved forms in laboratory environments. Chemists preparing solutions calculate concentration by weighing the solid and dissolving it in an appropriate solvent—sometimes at high purity for reactions, other times as analytical standards. High-purity, dry sample handling reduces risk of contamination and ensures predictable behavior during assays or synthesis. Material packed as pearls or granules offers convenience for automation or volume measurement, simplifying workflow for labs and production lines. The adaptability of this compound’s physical form supports a wide range of industries, from pharmaceuticals to specialty polymers, adhesives, and agrochemical research.
