Product Name: Trimethylsilylimidazole
Synonyms: TMSI, 1-Trimethylsilylimidazole
CAS Number: 18156-74-6
Recommended Use: Laboratory chemical, derivatization reagent
Manufacturer: [Manufacturer Name, Address, Emergency Contact Number]
GHS Classification: Flammable Liquids (Category 2), Skin Corrosion/Irritation (Category 2), Eye Damage/Irritation (Category 2A)
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor, Causes skin irritation, Causes serious eye irritation
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from open flames, Wear protective gloves/eye protection, Avoid breathing vapors, Wash thoroughly after handling
Chemical Name: 1-Trimethylsilylimidazole
Concentration: >98%
CAS Number: 18156-74-6
Impurities: Not significant for standard laboratory use
Eye Contact: Rinse carefully with water for at least 15 minutes, remove contact lenses
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing
Inhalation: Move to fresh air, provide oxygen if breathing is difficult
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention immediately
Symptoms: Redness, stinging, irritation, coughing, difficulty breathing, possible burns
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide
Unsuitable Media: Direct water stream
Fire Hazards: Releases toxic fumes under fire conditions, vapors form explosive mixtures with air
Protective Equipment: Full protective gear, self-contained breathing apparatus
Special Procedures: Evacuate area, fight from safe distance, use water spray for cooling exposed containers
Personal Precautions: Wear chemical splash goggles, flame-resistant gloves, lab coat, ensure adequate ventilation
Environmental Precautions: Prevent runoff into sewers/drains, contain spilled material with inert absorbent
Cleanup Methods: Absorb with sand or inert material, place in a labeled container, ventilate area thoroughly
Handling: Use only in a fume hood, avoid inhalation and skin contact, keep away from heat and ignition sources, handle glassware cautiously
Storage: Store in tightly closed container in a dry, well-ventilated location, block out direct light and moisture, separate from oxidizers and acids
Exposure Limits: No OSHA/ACGIH established limits
Engineering Controls: Chemical fume hood, local exhaust ventilation
Personal Protective Equipment: Nitrile gloves, splash-proof goggles, lab coat, face shield for large volumes
Respiratory Protection: Use NIOSH/MSHA approved respirators under vapor-producing conditions
Hygiene Measures: Wash hands before eating, remove contaminated clothing, launder before reuse
Appearance: Clear, colorless liquid
Odor: Slightly amine-like
Odor Threshold: Not determined
Boiling Point: 187°C
Melting Point: -20°C
Flash Point: 42°C (closed cup)
Evaporation Rate: Not available
Flammability: Highly flammable liquid
Vapor Pressure: 0.8 mm Hg at 25°C
Solubility: Miscible with common organic solvents, immiscible with water
Density: 0.98 g/cm³ at 25°C
pH: Not applicable
Partition Coefficient: Not available
Viscosity: Not available
Chemical Stability: Stable under recommended conditions
Incompatible Materials: Water, oxidizing agents, acids
Hazardous Reactions: May hydrolyze in moist air, releases flammable vapors
Decomposition Products: Carbon oxides, nitrogen oxides, silicon oxides, hydrogen cyanide under fire conditions
Conditions to Avoid: Heat, open flames, moisture, sources of ignition
Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: Causes irritation to eyes, skin, respiratory tract, may cause burns
Chronic Effects: Prolonged contact can lead to dermatitis
Toxicity Data: Not fully established for Trimethylsilylimidazole, data on analogs suggests moderate acute toxicity
Sensitization: Not reported
Mutagenicity/Carcinogenicity: No data indicating mutagenic or carcinogenic hazard
Reproductive Toxicity: No studies found
Ecotoxicity: Expected to be toxic to aquatic life with short-term exposure
Persistence/Degradability: Hydrolyzes gradually in water, not readily biodegradable
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Low, binds to soil
Other Adverse Effects: Avoid release to the environment, harmful in larger quantities
Disposal Methods: Dispose as hazardous organic waste, follow local/state/federal regulations
Container Disposal: Triple rinse, puncture and dispose through approved waste hauler
Precautions: Keep out of waterways, do not landfill large volumes
Waste Codes: Consult applicable authorities for hazardous waste classification
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (contains Trimethylsilylimidazole)
Transport Hazard Class: 3 (Flammable Liquids)
Packing Group: III
Label: Flammable Liquid
Special Precautions: Keep separated from oxidizers and foodstuffs, handle containers cautiously
US TSCA Inventory: Listed
SARA Title III: Not subject to Section 313 reporting
RCRA Status: Identified as hazardous waste by characteristic
OSHA Status: Regulated as hazardous chemical
WHMIS Classification (Canada): B2 (Flammable liquid), D2B (Toxic Material Causing Other Toxic Effects)
EU Regulation: Classified as dangerous, hazard symbols F, Xi
Other Regulations: State and country-specific workplace safety regulations apply
