Chemical Name: Trans-4-Phenyl-L-Proline
Synonyms: (2S,4R)-4-Phenylpyrrolidine-2-carboxylic acid
CAS Number: 87685-24-9
Formula: C11H13NO2
Molecular Weight: 191.23 g/mol
Recommended Use: Laboratory research, pharmaceutical intermediate
Supplier Details: Manufacturer name, address, phone number, and emergency contact information included on packaging
Potential Hazards: May cause respiratory and skin irritation, eye irritation possible on contact, ingestion may induce discomfort
GHS Classification: Not classified as hazardous under GHS criteria but general caution applies
GHS Label: None mandated, general warning symbols for chemicals recommended
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Health Effects: Temporary symptoms such as eye redness, throat discomfort, or rash
Environmental Hazards: No data suggesting substantial environmental impact, avoid bulk release
Substance: Trans-4-Phenyl-L-Proline
Purity: ≥ 98%
Impurities: Not considered significant for safety risk, trace synthesis byproducts possible
Additives: No hazardous additives included
Inhalation: Move affected person to fresh air, keep at rest in a position comfortable for breathing, seek medical attention if symptoms persist
Skin Contact: Wash immediately with mild soap and water, remove contaminated clothing, consult medical personnel for persisting irritation
Eye Contact: Rinse gently with water for several minutes, remove contact lenses if present, continue rinsing, seek medical advice for pain
Ingestion: Rinse mouth, do not induce vomiting, drink water to dilute, seek medical attention as soon as possible
Suitable Extinguishing Agents: Use water spray, foam, dry chemical powder, carbon dioxide
Special Hazards: Combustion may produce carbon monoxide, carbon dioxide, and nitrogen oxides
Protective Gear: Firefighters should wear self-contained breathing apparatus and protective clothing to guard against toxic fumes
Advice for Firefighters: Avoid runoff containing chemical residue, remain upwind from fire, use standard fire suppression tactics
Personal Precautions: Wear gloves, goggles, and lab coat, ventilate area, avoid breathing dust. Evacuate unnecessary personnel
Environmental Precautions: Prevent material from entering drains, surface waters, or soil
Clean-up Methods: Collect spilled material mechanically, place in suitable waste container, wash affected area with plenty of water, dispose in accordance with local regulations
Handling: Use appropriate personal protection, handle in a fume hood or well-ventilated area, minimize dust formation. Avoid contact with skin, eyes, and clothing, practice routine hygiene
Storage: Store at room temperature in a tightly closed container, keep away from strong acids, bases, oxidizing agents. Label container properly, restrict access to authorized personnel
Engineering Controls: Work in a laboratory hood or ventilated area, use dust control methods for bulk seed work
Respiratory Protection: Wear NIOSH-approved particulate respirator if risk of dust or aerosol formation exists
Hand Protection: Use chemical-resistant gloves (nitrile or latex)
Eye Protection: Use safety goggles or glasses with side shields
Skin Protection: Wear lab apron or protective clothing
Hygiene Practices: Wash hands after handling, do not eat, drink, or smoke in work area
Appearance: White to off-white solid, crystalline powder
Odor: Odorless
Melting Point: 183-186°C
Solubility: Soluble in water, DMSO, methanol
pH (1% Solution): Approx. 5.0 to 7.0
Boiling Point: Decomposes before boiling
Vapor Pressure: Not applicable (solid at room temperature)
Flash Point: Not determined
Density: 1.28 g/cm³
Partition Coefficient (log Pow): Not available
Chemical Stability: Stable under normal temperatures and conditions
Conditions to Avoid: Strong heat, open flame, prolonged exposure to air or light can affect quality
Incompatible Materials: Strong oxidizers, strong acids or bases
Hazardous Decomposition: Produces carbon oxides, nitrogen oxides upon combustion or decomposition
Acute Toxicity: No acute toxicity data available for the compound, based on structure considered low toxicity
Irritation: Exposure may cause temporary irritation to eyes and skin
Sensitization: Not reported, avoid repeated contact to prevent allergic reaction
Chronic Effects: No confirmed long-term health hazards documented
Routes of Entry: Inhalation, ingestion, skin and eye contact
Carcinogenicity: Not listed as carcinogenic by NTP, IARC, OSHA
Mutagenicity: Not reported
Reproductive Toxicity: Not reported
Eco-toxicity: Not considered highly toxic to aquatic life or plants at laboratory levels
Persistence and Degradability: Expected to degrade through standard biological processes
Bioaccumulative Potential: Low likelihood due to the nature of the chemical structure
Mobility in Soil: Limited data, not expected to migrate extensively
Other Adverse Effects: Keep large quantities out of waterways as best environmental practice
Waste Disposal Methods: Collect unused material in appropriate hazardous waste containers, incinerate or landfill through licensed waste disposal contractor
Contaminated Packaging: Clean thoroughly or dispose as chemical waste according to local, state, and federal requirements
Special Considerations: Keep records of disposal, prevent environmental contamination
UN Number: Not regulated as dangerous goods by transport legislation
Proper Shipping Name: Trans-4-Phenyl-L-Proline
Transport Hazard Class: None assigned
Packing Group: None assigned
Environmental Hazards: Not classified as marine pollutant
Special Precautions for User: Keep package secure, avoid damage in transit, follow relevant local regulations
Safety, Health and Environmental Regulations: Not listed as a controlled substance, falls under general chemical regulatory guidelines for laboratory and industrial users
OSHA: Not specifically regulated, handle according to laboratory safety practices
TSCA: Listed or exempt from listing
REACH: Pre-registered, substance handled as per general safety guidance
SARA Title III: Not a reportable substance
Other Regulations: Always review local, state, and federal guidelines related to chemical usage and disposal to maintain compliance and safety
