Product Name: Thiophen-2-Ethanol
Chemical Name: 2-(2-Thienyl)ethanol
Synonyms: 2-Thiopheneethanol, 2-Thienylethanol
Recommended Uses: Laboratory chemicals, pharmaceutical ingredients, fragrance manufacturing, specialty chemical synthesis
Company Info: Manufacturer: Specialty Chemical Supplier, Contact Phone: +1-800-555-XXXX, Address: 245 Science Lane, Chem City, USA
Emergency Telephone: +1-800-555-1212
CAS Number: 5408-74-2
Molecular Formula: C6H8OS
Molecular Weight: 128.19 g/mol
GHS Classification: Flammable liquid (Category 4), Skin irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity-single exposure (Category 3, Respiratory system)
Signal Word: Warning
Hazard Statements: H227: Combustible liquid. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
Pictograms: Exclamation mark
Precautionary Statements: P210: Keep away from heat/sparks/open flames/hot surfaces. P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P280: Wear protective gloves/eye protection/face protection.
Potential Health Effects: Inhalation may cause throat and lung irritation, headaches, dizziness; skin absorption and contact may result in redness, dryness, or dermatitis; eye contact leads to pain, redness, watering.
Environmental Hazards: Harmful to aquatic life with long-lasting effects.
Substance: 2-(2-Thienyl)ethanol
CAS Number: 5408-74-2
Concentration: ≥99% by weight
Impurities: Minor traces of related thiophene derivatives and ethanol derivatives, no significant impurities affecting classification.
Inhalation: Move person to fresh air, keep at rest, loosen tight clothing. Monitor for breathing difficulty, seek medical attention if symptoms persist. Do not allow patient to leave unaccompanied if dizzy or confused.
Skin Contact: Wash with plenty of soap and water for at least 15 minutes. Remove contaminated clothing or shoes and wash before reuse. If irritation develops or persists, call a physician.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, continue rinsing. Seek medical advice if irritation continues.
Ingestion: Rinse mouth thoroughly, do not induce vomiting. Give small amount of water if conscious. Get immediate medical attention.
Most Important Symptoms: Redness, pain, dryness, headaches, cough, dizziness, irritation.
Advice for Physicians: Treat symptomatically and supportively. Monitor airway and respirations closely.
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical powder, water spray. Do not use straight water jet as it can spread fire.
Hazards from Combustion: Burning releases irritating and toxic fumes including carbon monoxide, carbon dioxide, sulfur oxides.
Protective Equipment: Firefighters require full protective gear and self-contained breathing apparatus.
Special Procedures: Move containers away from fire if safe. Cool fire-exposed containers with spray water. Avoid inhaling combustion gases. Prevent firewater runoff from entering the environment.
Personal Precautions: Evacuate non-essential personnel, ventilate area. Wear gloves, goggles, and protective clothing. Avoid inhaling vapors or skin contact.
Environmental Precautions: Prevent from entering drains, sewers, waterways, or soil. Notify local authorities if environmental contamination occurs.
Containment: Absorb small spills with inert material (sand, diatomaceous earth). Sweep up and place in suitable sealed container for disposal.
Cleaning Up: Flush spill area with water after collection. Properly ventilate area and avoid raising dust/vapor clouds.
Handling: Use in well-ventilated areas or under fume hood. Avoid breathing vapors, prevent skin and eye contact. Wear protective gloves, chemical goggles, and lab coat. No eating, drinking, or smoking during use.
Storage: Store in tightly closed original container in a cool, dry, well-ventilated place, away from incompatible substances (strong oxidizing agents). Keep away from heat, sparks, open flame, and direct sunlight. Store at room temperature (15–25°C).
Special Requirements: Clearly label storage containers. Ground and bond containers when transferring material.
Exposure Limits: No OSHA, ACGIH, or NIOSH exposure limits established for this substance.
Engineering Controls: Use local exhaust ventilation or process enclosures. Maintain eyewash stations and safety showers nearby.
Personal Protective Equipment: Chemical-resistant gloves (nitrile), safety goggles or face shield, lab coat or apron, suitable respirator when airborne concentrations are high.
Hygiene Measures: Wash hands thoroughly after handling, remove protective equipment before leaving work area, wash contaminated clothing before reuse.
Appearance: Colorless to pale yellow liquid
Odor: Sweet, slightly sulfurous, aromatic odor
Odor Threshold: Not established
pH: Not determined (not relevant for non-aqueous liquid)
Melting Point: -20°C
Boiling Point: 230–235°C
Flash Point: 95°C (closed cup)
Evaporation Rate: Not determined
Flammability: Combustible liquid
Vapor Pressure: 0.2 mm Hg at 20°C
Vapor Density: 4.4 (air = 1)
Relative Density: 1.16 g/cm³ at 20°C
Solubility: Low solubility in water; soluble in organic solvents such as ethanol, ether, and chloroform
Partition Coefficient (log Kow): 1.7
Auto-ignition Temperature: 351°C
Decomposition Temperature: Not determined
Viscosity: Not determined
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Non-reactive under normal safety conditions.
Conditions to Avoid: Heat, flames, sparks, electrostatic charges, exposure to air/moisture for prolonged periods.
Incompatible Materials: Strong oxidizers such as peroxides, nitric acid, chlorine, and high-energy oxidizing reagents.
Hazardous Decomposition: Toxic and irritating fumes including thiophene derivatives, carbon oxides, and sulfur oxides upon heating or combustion.
Acute Toxicity: Oral LD50 (rat): >500 mg/kg. Not classified as acutely toxic based on available data.
Skin Irritation: Causes irritation and possible dermatitis on repeated exposure.
Eye Irritation: Causes severe irritation, redness, and watering.
Respiratory Sensitization: Vapor inhalation may cause temporary coughing, sore throat, dizziness.
Chronic Effects: Prolonged or repeated skin exposure may produce fissures and redness.
Carcinogenicity: Not listed as carcinogenic (NTP, IARC, OSHA).
Reproductive/Developmental Effects: No evidence for mutagenicity, teratogenicity, or reproduction toxicity in accessible data.
Target Organs: Eyes, skin, respiratory system.
Aquatic Toxicity: Harmful to aquatic organisms. Low to moderate toxicity expected for fish and invertebrates (EC50: 10–100 mg/L).
Persistence & Degradability: Not readily biodegradable. Breakdown in the environment occurs slowly.
Bioaccumulation Potential: Some bioaccumulation possible (log Kow = 1.7 suggests moderate potential).
Mobility: Low mobility in soil due to slight polarity and water solubility.
Other Ecological Data: Not considered highly toxic but should be prevented from entering waterways. No evidence for major long-range transport or ozone depletion.
Waste Disposal Methods: Dispose of as hazardous chemical waste in accordance with local, state, and federal regulations. Incineration in an approved facility offers preferred disposal route.
Contaminated Packaging: Rinse containers thoroughly, then offer for controlled recycling or disposal. Avoid reuse of contaminated containers.
Disposal Precautions: Do not flush to sewer, soil, or surface waters. Consult authorities before on-site treatment options.
UN Number: Not classified as dangerous for transport by UN regulations.
UN Proper Shipping Name: Not regulated as hazardous for transportation.
Transport Hazard Class: None assigned
Packing Group: None assigned
Transport Labels: None required
Marine Pollutant: Not considered a marine pollutant under IMDG code
Special Precautions: Protect containers from physical damage, avoid extreme temperatures during transit. Ensure secure, upright packing to prevent leaks.
OSHA Hazards: Skin and eye irritant, combustible liquid
TSCA Inventory: Listed
SARA 302/304/313: Not listed as a regulated substance under these sections
California Prop 65: Not listed as a chemical known to cause cancer or reproductive toxicity
REACH Status (EU): Substance registered or exempt
WHMIS Classification (Canada): D2B (Skin/Eye Irritant)
Other Regulations: Follow all local, regional, and national legislation for safe handling and use. SDS available to workers and emergency responders.
