Chemical Name: Thiamorpholine
Synonyms: 1-Thia-4-azacyclohexane
CAS Number: 123-89-9
Recommended Use: Industrial chemical for use in organic synthesis and research laboratories
Manufacturer: [Manufacturer Name and Address]
Emergency Contact: [Phone number for emergencies]
Molecular Formula: C4H9NS
Molecular Weight: 103.18 g/mol
GHS Classification: Acute Toxicity (Oral) Category 4, Skin Corrosion/Irritation Category 2, Eye Damage/Irritation Category 2A
Signal Word: Warning
Hazard Statements: Harmful if swallowed; Causes skin irritation; Causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or vapor; Wash hands thoroughly after handling; Wear protective gloves and eye protection
Route of Exposure: Inhalation, skin contact, eye contact, ingestion
Potential Health Effects: Exposure may cause respiratory discomfort, skin burns, or eye redness
Substance: Thiamorpholine
Concentration: 100%
Impurities: Trace amounts of related cyclic amines may be present depending on manufacture
Other components: No additives or stabilizers
Inhalation: Move person to fresh air. Seek medical help if symptoms such as coughing or shortness of breath continue.
Skin Contact: Remove contaminated clothing. Wash skin with soap and plenty of water for several minutes. Medical attention recommended for burns or persistent irritation.
Eye Contact: Rinse immediately with water for at least 15 minutes, holding eyelids open. If discomfort continues, see physician.
Ingestion: Rinse mouth with water. Do not induce vomiting. Medical evaluation advised.
Most important symptoms: Burning sensation, redness, pain, possible headache or dizziness after inhalation
Medical attention: Symptomatic treatment, monitor respiratory function if exposed to high concentration
Suitable Extinguishing Media: CO2, dry chemical, foam, or water spray
Special Hazards: Emits toxic fumes of nitrogen oxides and sulfur oxides on combustion
Advice for Fire-Fighters: Wear self-contained breathing apparatus and full protective gear
Unusual Fire Hazards: Vapors may be heavier than air, spreading along the ground or to a distant ignition source
Fire Fighting Procedures: Approach upwind to avoid hazardous vapors; use caution as runoff water may cause environmental contamination
Personal Precautions: Use gloves, eye protection, and respiratory protection if needed; avoid breathing vapors
Environmental Precautions: Prevent spillage from entering drains or open water
Cleanup Procedures: Absorb with inert material (sand, earth, vermiculite); collect in sealed containers for disposal; wash spill area thoroughly after cleanup
Notification: Notify authorities if significant spill contaminates water or soil
Decontamination: Wear protective clothing and ventilate area during cleanup
Handling: Work in a well-ventilated area; avoid direct contact with skin or eyes; keep containers sealed when not in use
Incompatibilities: Strong oxidizers, acids, and alkylating agents
Storage: Keep in tightly closed containers in a cool, dry place; protect from moisture and sources of ignition
Transfer Precautions: Ground/bond container during transfer to avoid static discharge
Occupational Exposure Limits: No established limit; minimize exposure as a general practice
Engineering Controls: Use local exhaust ventilation; use closed systems where possible
Eye/Face Protection: Chemical splash goggles
Skin Protection: Gloves made from chemical-resistant materials such as nitrile or neoprene; lab coat or coveralls
Respiratory Protection: Use NIOSH-approved respirator if airborne concentrations exceed recommended limits
Hygiene Measures: Wash hands and face after use; remove and clean contaminated clothing before reuse
Appearance: Colorless to light yellow liquid
Odor: Amine-like, somewhat rotten egg odor
Melting Point: -15°C
Boiling Point: 175°C
Vapor Pressure: Low at room temperature
Solubility (water): Miscible
Density: 1.13 g/cm³
pH: Alkaline solution in water
Flash Point: 70°C (closed cup)
Evaporation Rate: Slow under ambient conditions
Partition Coefficient (Log Kow): Not available
Viscosity: Slightly viscous, typical of small amines
Stability: Stable under recommended storage conditions
Hazardous Reactions: May react with acids to form salts and release heat; reacts vigorously with oxidizing agents
Conditions to Avoid: High temperatures, open flames, incompatible chemicals
Decomposition Products: Nitrogen oxides, sulfur oxides, and other hazardous compounds possible on burning
Polymerization: Not expected to occur under normal use
Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Effects: Oral toxicity LD50 (rat): 580 mg/kg
Skin: Causes irritation, can cause burns on prolonged contact
Eye: May cause severe irritation, redness, possible damage with extended exposure
Chronic Effects: Prolonged exposure could lead to dermatitis or sensitization; no long-term studies identified
Carcinogenicity: Not classified as carcinogenic based on available data
Mutagenicity: No evidence in standard assays
Other health concerns: Harmful if swallowed, can cause respiratory distress in high concentrations
Toxicity to Aquatic Life: Expected to be harmful to aquatic organisms based on structure and effects of related compounds
Persistence and Degradability: Likely to degrade slowly in water; not readily biodegradable
Bioaccumulation Potential: Low potential due to high water solubility
Mobility in Soil: Expected to be highly mobile in water and soil
Other adverse effects: Spills can lower water quality and disrupt aquatic systems
Precautions: Avoid environmental release, especially in large quantities
Waste Disposal Methods: Dispose of contents and container in accordance with local, regional, national, and international regulations
Recommended Disposal: Incinerate with chemicals that can neutralize amines; consult hazardous waste handler
Contaminated Packaging: Rinse thoroughly, then discard as hazardous waste
Special Precautions: Do not dispose down drains or into natural waterways
UN Number: 2734
Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (contains Thiamorpholine)
Transport Hazard Class: 8 (Corrosive liquid)
Packing Group: II
Labels: Corrosive
Special Provisions: Protect from heat and keep away from food during transit; make sure containers are sealed and labeled correctly
Other Remarks: Follow all national and local transport regulations to avoid accidental exposure during movement
TSCA (US): Listed
EU REACH: Registered or pre-registered
OSHA Status: Not specifically regulated, general chemical hygiene applies
WHMIS (Canada): D2A (Toxic) and E (Corrosive Material)
SARA Title III: Not listed under hazardous substances or extremely hazardous substances
Other regulations: Local workplace safety rules may require risk assessment and exposure controls on site
Labeling Requirements: Workplace containers must be labeled clearly with hazards and first aid information
