Product Name: Tert-Butyl Piperazine-1-Carboxylate
Chemical Formula: C9H18N2O2
CAS Number: 57260-70-7
Other Names: 1-Piperazinecarboxylic acid, 4-methyl-, 1,1-dimethylethyl ester
Recommended Use: Laboratory chemical, chemical synthesis intermediate
Supplier: Contact chemical manufacturer or distributor
Emergency Contact: Refer to local emergency telephone numbers for chemical incidents
GHS Classification: Acute Toxicity – Oral Category 4, Eye Irritation Category 2A, Skin Irritation Category 3
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes serious eye irritation, causes mild skin irritation
Precautionary Statements: Avoid contact with skin and eyes, do not eat, drink or smoke when using, wash thoroughly after handling, wear appropriate protective gloves and eye/face protection, if swallowed: call a poison center or doctor
Potential Health Effects: Inhalation may cause respiratory irritation, ingestion may lead to nausea and abdominal discomfort, contact may provoke redness or slight burns to skin and eyes
Environmental Concerns: Possible risk of harm to aquatic life if released in large quantities
Chemical Name: Tert-Butyl Piperazine-1-Carboxylate
Purity: Greater than 98%
CAS Number: 57260-70-7
Molecular Weight: 186.25 g/mol
Synonyms: Boc-piperazine, N-Boc-piperazine
Impurities: Less than 2%, unspecified trace process impurities typical for chemical synthesis grade
Inhalation: Move person to fresh air, keep at rest in a comfortable position, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, wash affected area thoroughly with water and soap, get medical attention for persistent irritation or burns
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical help for persistent pain or redness
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical personnel, call doctor or poison control center immediately
Suitable Extinguishing Media: Use carbon dioxide, powder, foam or water spray for small fires
Unsuitable Media: Avoid direct water jet for large liquid spills as it may spread fire
Specific Hazards: Combustion may produce carbon oxides, nitrogen oxides, hazardous fumes
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear
Precautions: Prevent run-off from entering drains or open water sources, ventilate area to disperse fumes after fire is controlled
Personal Precautions: Wear protective gloves, goggles, and suitable protective clothing, ensure adequate ventilation
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid discharge to drains, surface and ground water
Cleanup Methods: Absorb spill with inert material (sand, diatomaceous earth), collect in suitable closed containers for disposal, wash residue with plenty of water, ventilate affected area thoroughly
Precautions for Safe Handling: Use in well-ventilated areas, avoid direct contact with hands, eyes, or skin, keep away from incompatible materials which include strong oxidizers and acids
Hygiene Practices: Wash hands after handling, do not eat or drink in working areas, remove contaminated clothing and wash before reuse
Storage Conditions: Store tightly closed in cool, well-ventilated place away from heat and direct sunlight, keep container upright and dry, segregate from volatile organics and strong acids
Exposure Limits: No occupational exposure limits established by OSHA, ACGIH, or NIOSH
Engineering Controls: Ensure adequate local exhaust ventilation and general ventilation in work area
Personal Protective Equipment: Chemical-resistant gloves, tightly sealed safety goggles, lab coat or apron, use of suitable respirator for higher vapor or dust levels
Environmental Controls: Implement spill containment to prevent run-off, utilize closed systems where feasible
Appearance: White to off-white crystalline solid or powder
Odor: Mild characteristic odor
pH: Not applicable (solid, not aqueous)
Melting Point: 58–62°C
Boiling Point: Data not available, decomposes before boiling
Flash Point: >100°C (estimated, not highly flammable)
Solubility: Soluble in organic solvents such as dichloromethane, slightly soluble in water
Vapor Pressure: Low at ambient conditions
Density: 1.06 g/cm³
Partition Coefficient (log Kow): Data not available
Other Data: Stable under standard handling conditions, handle with dry clean tools
Chemical Stability: Stable under normal temperatures and dry conditions
Reactive Hazards: May react with strong acids, oxidizing agents, or bases
Conditions to Avoid: Excessive heat, moisture, strong sunlight, ignition sources
Hazardous Decomposition Products: Under fire or thermal decomposition, may release carbon monoxide, carbon dioxide, nitrogen oxides, and irritating vapors
Polymerization: Will not occur under standard storage and use conditions
Acute Toxicity: Estimated oral LD50 in rats between 500–2000 mg/kg (harmful if swallowed)
Inhalation: May irritate respiratory tract if dust or vapors inhaled
Skin Contact: May cause mild skin irritation, especially after prolonged exposure
Eye Contact: Risk of significant irritation, redness, tearing, possible injury from particulate
Chronic Effects: Repeated or prolonged exposure may cause dermatitis or allergic reactions in sensitive individuals
Other Effects: Not identified as a carcinogen, mutagen or reproductive toxicant by major agencies
Target Organs: Eyes, skin, respiratory tract
Ecotoxicity: No long-term aquatic toxicity data available, precaution advised for accidental release in large quantities to watercourses
Persistence and Degradability: Likely not readily biodegradable; persistence probable in soil and aquatic environments
Bioaccumulation Potential: Unknown, but likely low due to low water solubility
Mobility in Soil: Low potential for migration based on structure and physical properties
Other Adverse Effects: Avoid release to environment, inform authorities in case of large spill
Waste Treatment Methods: Dispose of contents and container in accordance with local, regional, national and international regulations
Product Disposal: Use authorized chemical waste disposal providers, prefer incineration under controlled conditions
Packaging Disposal: Puncture, triple rinse and recycle or dispose as hazardous waste
Special Precautions: Do not discharge into drains or the environment, minimize material waste and residues
UN Number: Not regulated by international transport statutes for hazardous materials
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Proper Shipping Name: Chemical substance, non-hazardous
Transport Precautions: Secure packaging to prevent release in transit, keep away from incompatible goods, transport in accordance with current safety laws and regulations
Inventory Status: Listed on TSCA, REACH and other major chemical inventories
Classification: Not classified as hazardous for transport, regulated for occupational and environmental safety
Labeling Obligations: Must carry hazard labeling per GHS requirements
SARA/OSHA: Not listed as extremely hazardous, not a SARA Title III Section 313 chemical
Other Regulations: Ensure compliance with state chemical reporting requirements, maintain detailed workplace safety records for handling and accidental exposures
