Material Safety Data Sheet (MSDS) – Succinimide

Identification

Chemical Name: Succinimide
Synonyms: Amber acid imide, butanimide, succinamic anhydride
Chemical Formula: C4H5NO2
Molecular Weight: 99.09 g/mol
CAS Registry Number: 123-56-8
Use: Manufacturing of pharmaceuticals, as an intermediate in organic synthesis, research laboratory reagent.
Supplier Contact: Provided on request or packaging, with emergency phone numbers available.

Hazard Identification

GHS Classification: Not classified as hazardous under GHS regulations in its pure form
Health Effects: Irritation to eyes, skin, and respiratory tract; ingestion or inhalation in large quantities may produce systemic effects
Label Elements: Signal Word: None; Hazard statements: None required under GHS
Potential Exposure Routes: Inhalation, ingestion, skin and eye contact
Symptoms of Exposure: Redness, itching, tearing of eyes; skin dryness; cough or sore throat after inhalation
Chronic Exposure Risks: No long-term health effects reported for low-level occupational exposures
NFPA Ratings: Health: 1; Flammability: 1; Reactivity: 0

Composition / Information on Ingredients

Chemical Identity: Succinimide
Concentration: ≥99% pure
Contaminants: Trace impurities only, often less than 1% total
Other Ingredients: Not present in significant quantities
Classification: Organic compound, cyclic imide

First Aid Measures

Inhalation: Move to fresh air immediately; monitor for breathing difficulty; seek medical care for sustained symptoms
Skin Contact: Remove contaminated clothing; wash area with soap and water for at least 15 minutes; medical advice if irritation develops
Eye Contact: Rinse slowly and gently with water for 15-20 minutes; keep eyelids open; medical attention if vision blurs or irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting unless directed; seek prompt medical assistance for large amounts
Most Important Symptoms: Local skin or eye irritation, possible gastrointestinal distress

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, or water spray for small fires
Fire Hazards: Mild fire risk; emits nitrogen oxides and carbon oxides when burned
Protective Equipment: Full protective clothing and self-contained breathing apparatus required for major fires
Special Procedures: Cool containers with water spray to prevent rupture; avoid inhaling fumes; evacuate unnecessary personnel
Unusual Combustion Products: Toxic gases including nitrous fumes may develop

Accidental Release Measures

Personal Protection: Wear chemical resistant gloves, goggles, lab coat; use local exhaust ventilation
Spill Cleanup: Sweep up solid spill carefully; avoid dust formation; collect in suitable sealed container
Environmental Precautions: Prevent further leakage or spillage if safe; avoid discharge into drains or natural waterways
Decontamination: Wash spill site thoroughly after clean-up
Disposal: Dispose of waste according to local environmental regulations, generally through licensed chemical waste disposal contractor

Handling and Storage

Handling Precautions: Use in well-ventilated area; avoid breathing dust or contacting skin and eyes; wash hands after handling
Storage Conditions: Store in tightly sealed containers, in a cool, dry, well-ventilated place away from strong oxidizers
Incompatible Materials: Strong acids, strong bases, and strong oxidizing agents
Specific Use Recommendations: Only trained personnel should handle; label containers clearly; keep away from food and beverages

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific limits established for succinimide
Engineering Controls: Local exhaust ventilation or general dilution ventilation
Personal Protective Equipment: Chemical resistant gloves (nitrile, latex), splash proof goggles, protective clothing
Respiratory Protection: Dust mask or respirator if dust levels exceed exposure limits or if ventilation is insufficient
Hygiene Measures: Wash thoroughly with soap and water after handling; avoid eating or drinking in work areas

Physical and Chemical Properties

Physical State: White crystalline solid
Odor: Essentially odorless
Melting Point: 123-125 °C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water; moderately soluble in ethanol
Density: Approximately 1.44 g/cm3
pH: Slightly acidic to neutral (5-7 for 10% solution)
Vapor Pressure: Negligible at room temperature
Flash Point: Not applicable; not classified as flammable

Stability and Reactivity

Chemical Stability: Stable under normal conditions of storage and use
Reactive Conditions: Decomposes upon heating; avoid high temperatures
Possible Hazardous Reactions: Reaction with strong oxidizers may produce hazardous byproducts
Incompatible Substances: Strong acids and oxidizers, alkali, reducing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide

Toxicological Information

Acute Toxicity: Oral LD50 (rat): 5000 mg/kg; considered to have low toxic potential at typical laboratory or industrial exposures
Skin Irritation: Mild irritant at high concentrations or prolonged contact
Eye Effects: Mild irritant
Respiratory Sensitization: Not classified as a respiratory sensitizer
Chronic Effects: No known chronic toxicity based on available animal studies or workplace observation
Carcinogenicity: Not listed by NTP, IARC, or OSHA as a carcinogen
Routes of Exposure: Inhalation, ingestion, dermal, ocular

Ecological Information

Ecotoxicity: No known significant adverse ecological effects; data limited but low toxicity observed in aquatic environments
Mobility in Soil: Expected to have moderate mobility based on solubility in water
Persistence and Degradability: Readily biodegradable under aerobic conditions
Bioaccumulative Potential: Not expected to bioaccumulate; low log Kow
Other Adverse Effects: Spill may cause short-term alteration to local pH and oxygen demand

Disposal Considerations

Waste Disposal Methods: Dispose of as chemical waste in accordance with local, regional, or national environmental regulations; incineration or landfill at permitted facility
Packaging: Use sealed, clearly labeled containers for all waste; do not reuse containers that have held hazardous chemicals
Special Precautions: Avoid release into the environment; contact licensed professional waste disposal service
Contaminated Packaging: Clean thoroughly before reuse, otherwise dispose of as chemical waste

Transport Information

UN Number: Not regulated for transport
Proper Shipping Name: Succinimide
Hazard Class: Not classified as dangerous for road, rail, air, or sea
Packing Group: Not applicable
Special Precautions: Transport in securely closed containers
Environmental Precautions: Avoid spillage during loading/unloading; keep away from incompatible materials

Regulatory Information

OSHA: Not listed as hazardous under 29 CFR 1910.1200
SARA Title III: Not subject to reporting under sections 302, 304, or 313
TSCA Status: Listed in the Toxic Substances Control Act (TSCA) inventory
WHMIS Classification (Canada): Not controlled product
REACH Registration: Exempted or registered as per current European Union guidelines
Labeling Requirements: Standard chemical labeling required; warnings for minor irritation risk