Material Safety Data Sheet: Sodium 5-Oxo-DL-Prolinate

Identification

Product Name: Sodium 5-Oxo-DL-Prolinate
Synonyms: Sodium pyroglutamate
Chemical Formula: C5H6NNaO3
CAS Number: 6616-87-1
EC Number: 229-611-4
Recommended Use: Laboratory research, cosmetic ingredient, industrial additive
Supplier: Contact local supplier or manufacturer’s details on packaging label
Emergency Contact: Refer to national emergency telephone number

Hazard Identification

Classification: Not classified as hazardous under global GHS standards
Signal Word: None
Hazard Statements: No significant hazards anticipated in normal conditions
Pictograms: No applicable hazard pictograms
Precautionary Statements: Avoid dust inhalation, minimize direct skin and eye contact
Potential Effects: Eye and skin irritation possible with prolonged or repeated exposure

Composition / Information on Ingredients

Chemical Name: Sodium 5-Oxo-DL-Prolinate
Concentration: 98-100% by weight
Impurities: None expected at relevant concentrations
Stabilizing Additives: None

First Aid Measures

Eye Contact: Rinse gently with water for at least 15 minutes, lift eyelids frequently, remove contact lenses if present
Skin Contact: Wash with soap and water, remove contaminated clothing, consult physician in case of inflammation or persistent irritation
Inhalation: Move person to fresh air, maintain unobstructed breathing, get medical help if symptoms linger
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, provide water to dilute, seek medical advice if discomfort occurs

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet may scatter powder
Specific Hazards: Decomposition can release oxides of nitrogen and carbon
Protective Equipment: Wear self-contained breathing apparatus and chemical protective clothing
Instructions: Avoid breathing combustion gases, keep containers cool by spraying with water if fire threatens

Accidental Release Measures

Personal Precautions: Use dust mask, chemical-resistant gloves, avoid direct contact with spill
Environmental Precautions: Prevent product from entering drains, sewers, or waterways
Cleanup Methods: Sweep up and collect in appropriate containers, minimize dust formation, ventilate area, wash spill site after material pickup

Handling and Storage

Handling: Avoid generating or breathing dust, use localized ventilation, wear approved PPE, keep away from food and drink
Storage: Store in tightly sealed original packaging, in well-ventilated, cool, dry location, isolate from incompatible materials such as strong acids, protect from moisture and direct sunlight, clearly label storage location

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limits set
Engineering Controls: Use local exhaust or adequate general ventilation
PPE: Safety goggles, chemical resistant gloves, laboratory coat
Respiratory Protection: Dust mask or respirator if handling large quantities or creating airborne dust
Hygiene Measures: Wash hands thoroughly after handling, do not eat, drink, or smoke during use, keep separate from street clothing

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless
Melting Point: 185-190°C (decomposes)
Boiling Point: Not applicable
Solubility: Freely soluble in water, insoluble in non-polar solvents
pH (1% solution): Typically 7-9
Vapor Pressure: Negligible at room temperature
Density: 1.46 g/cm³ approx
Flash Point: Not flammable
Partition Coefficient (log Kow): Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended storage and handling conditions
Incompatible Materials: Strong acids, strong bases, powerful oxidizing agents
Hazardous Decomposition: May produce toxic fumes such as carbon monoxide, carbon dioxide, nitrogen oxides under fire or high heat
Polymerization: Does not occur
Conditions to Avoid: Exposure to moisture, high humidity, extreme temperatures, open flames

Toxicological Information

Acute Toxicity: Data not fully established; low acute toxicity expected based on structure and analogs
Routes of Exposure: Eyes, skin, inhalation, ingestion
Potential Effects: Irritation of eyes and skin on contact, mild respiratory tract discomfort if airborne dust is inhaled
Sensitization: Not expected to cause skin or respiratory sensitization
Chronic Effects: No long-term effects reported in literature at typical exposure levels

Ecological Information

Aquatic Toxicity: No data indicating high toxicity to aquatic life; readily dilutes in water
Persistence and Degradability: Expected to be biodegradable
Mobility in Soil: High water solubility implies significant mobility
Bioaccumulation Potential: Not likely due to low partition coefficient
Other Adverse Effects: Avoid release to environment; follow best practices for containment and disposal

Disposal Considerations

Waste Treatment Methods: Collect and place in suitable container for disposal according to local regulations
Disposal of Product: Incineration in authorized facilities or landfill at approved sites
Contaminated Packaging: Rinse thoroughly, dispose of as laboratory waste
Special Precautions: Do not allow significant quantities to reach groundwater, water bodies, or sewage systems, contact appropriate waste disposal authorities for guidance

Transport Information

UN Number: Not classified as dangerous for transport
Transport Hazard Class: Not subject to classification
Packing Group: None
Transport Label: None required
Special Precautions for Users: Keep container tightly closed and secure during transit, prevent damage or leakage

Regulatory Information

Labeling Requirements: Follow national and regional guidelines for chemical labeling
SDS Compliance: In accordance with OSHA Hazard Communication Standard and GHS
TSCA Inventory: Listed or exempt
REACH Registration: Not required at current import volumes
Relevant Safety, Health, and Environmental Regulations: Observe standard workplace safety practices, refer to regional chemical safety standards
Other Registration: Not scheduled under international chemical conventions