Sodium 5-Oxo-1-Palmitoyl-L-Prolinate didn't drop out of thin air; scientists chased new surfactants and emulsifiers through the late 20th century, as the personal care and pharmaceutical industries hunted for compounds with improved safety and functionality. Researchers looked at amino-acid-based molecules, especially those that blended fat-loving side chains and amino acid structures, after noticing n-acyl prolinates in natural systems like milk and skin. The race for safer, bio-inspired alternatives quickened when synthetic detergents caused skin irritation. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate drew attention in the 1980s and 1990s, thanks to its amphiphilic character and the push for milder, environmentally responsible ingredients. Chemical engineers tinkered with various fatty acid side chains until palmitoyl stuck out for skin tolerance and stability. Once the synthesis and purification methods became more consistent, large-scale production followed.
Most see Sodium 5-Oxo-1-Palmitoyl-L-Prolinate as a fine-to-granular, mildly hygroscopic powder or as a white-to-off-white solid. It flows reasonably well, resists caking if kept dry, and dissolves quickly in water, yielding a clear or slightly opalescent solution. It carries a balanced charge—thanks to the sodium salt—so it acts as an amphoteric, switching between positive and negative form depending on pH. This flexibility has put it in high demand for cleansers, shampoos, topical pharmaceutical blends, and several cosmetic emulsions. The substance draws attention for both gentleness and effectiveness; it breaks up dirt and grease, but doesn’t strip natural oils or aggravate sensitive skin. This makes it stand out compared to older, harsher surfactants such as sodium lauryl sulfate.
Sodium 5-Oxo-1-Palmitoyl-L-Prolinate usually carries a melting point in the range of 180-200°C, depending on purity and moisture. Its solubility in water is strong and almost immediate, but it doesn’t dissolve in most organic solvents, which limits its migration in formulations. The molecule contains a 16-carbon palmitoyl tail, giving it solid hydrophobic strength, plus a polar prolinate head which encourages micelle and vesicle formation in solution. In practical handling, it has a faint, fatty odor, not overwhelming or unpleasant, and doesn't carry the "chemical" tang found in many industrial surfactants. On chemical analysis, it resists light acid and base; strong hydrolysis or high heat eventually breaks it down. Its pH in solution sits close to neutral around 6.5-7.5, making it suitable for direct contact with skin or mucous membranes.
I’ve read plenty of technical sheets and the reliable ones always spell out the sodium salt percentage, residual moisture, and levels of free palmitic acid. Pharmaceutical grades define purity at 98% minimum, with tight limits on heavy metals and residual solvents. For cosmetics, labeling usually broadcasts non-GMO sourcing and allergen-free credentials. Commercial drums or bags display batch codes, country of origin, shelf-life (often two years in ideal storage), and highlight compliance with REACH, JP, and US Pharmacopeia as applicable. Ingredient panels list it by INCI name or chemical descriptor, but consumers spot synonyms like "n-Palmitoyl proline sodium" or "proline palmitate sodium salt" on overseas packaging. Clear, honest labeling gives manufacturers and regulators more room to check quality and trace origin, easing safety audits.
Production starts with the condensation of palmitoyl chloride and L-proline in an aqueous or alcoholic environment, using mild bases such as sodium hydroxide to scrub out HCl produced in the reaction. The sodium salt forms either directly or after an isolation and neutralization step if prepared via the acid form first. Large manufacturers prefer anhydrous synthesis to skip moisture issues, using vacuum drying and controlled temperatures. Some labs still swear by slow precipitation and overnight cooling, which gives bigger, purer crystals. A high degree of control keeps side products—mostly unreacted starting materials and partially hydrolyzed derivatives—at bay. The final product is filtered, washed with cold water, and vacuum-dried. Analytical chromatography checks for isomeric purity and absence of residual acids or amines, a must for pharma or personal care applications.
Sodium 5-Oxo-1-Palmitoyl-L-Prolinate offers a springboard for further chemistry. The amide linkage resists easy hydrolysis, but enzymes—including bacterial amidases—can slowly cleave it over time or under stress, releasing palmitate and proline. Acidic or basic hydrolysis at high temperatures speeds things up. If you want derivatives, it's straightforward to substitute the palmitoyl group with shorter-chain or unsaturated acyl groups using similar synthetic routes, swapping out palmitoyl chloride for other fatty acyl chlorides. Some research teams have PEGylated the free amine to boost water compatibility, chasing new surfactant or drug delivery properties. Others use the prolinate backbone as a scaffold for even more exotic modifications. These chemical backroads can yield new cleansers, emulsifiers, and penetration enhancers for topical treatments. Each tweak changes how the molecule sits in a formula, how hard it works, and sometimes its safety profile.
Regulatory filings and product data sheets reflect a catalog of synonyms. Aside from the IUPAC mouthful, the most familiar trade names include "Palmitoylproline Sodium," "Sodium Palmitoylprolinate," "Proline palmitate sodium," and "n-Palmitoyl proline sodium salt." In technical reference books and patent filings, you may spot it under identifiers like N-(hexadecanoyl)-L-proline sodium salt. Conservatively, more than a dozen variations crop up, each depending on house style, region, or product class. Some companies register brand-specific trade names as well, hoping for distinction in a crowded surfactant market. On exported consumer products, international labeling standards dictate which synonym appears. Without cross-referencing, buyers sometimes face confusion, especially crossing borders or referencing different compendia.
Occupational safety around Sodium 5-Oxo-1-Palmitoyl-L-Prolinate falls under standard chemical handling rules in most plants. Workers rely on gloves and dust masks when weighing or pouring, since fine particles easily irritate mucous membranes if airborne. Eye contact sometimes causes temporary redness; safety eyewear and eyewash stations are smart choices. Ingestion, though unlikely, leads to stomach upsets but hasn’t triggered systemic toxicity at typical concentrations. The Environmental Working Group rates it as a low-hazard ingredient, and North American Material Safety Data Sheets rarely flag chronic concerns. In large spills, warm water flushes clean quickly, with sodium salt and fatty acid byproducts breaking down safely in typical municipal water treatment systems. Many bulk users take extra steps to control dust and keep bags sealed, since moisture softens the powder and raises clumping risk.
Beyond the usual shampoo and cleanser territory, Sodium 5-Oxo-1-Palmitoyl-L-Prolinate claims a spot in dermatological ointments, baby wipes, wound hydration pads, and oral hygiene gels. Formulators like the mildness and its ability to blend with other actives without throwing off product texture or pH. I’ve seen it pull double duty—acting as a surfactant and moisturizing agent in leave-on skin lotions and rinse-off foam baths. Pet grooming runs with it for non-irritating cleaning. Medical device coatings sometimes tap its amphiphilic nature for improved biocompatibility, and it crops up as a penetration enhancer in topical drug delivery research. If a product designer needs to skirt sulfates, parabens, and harsh detergents, this molecule feels like cheating—it gives performance without compromise.
Biochemistry and skin science labs still run down new tweaks for Sodium 5-Oxo-1-Palmitoyl-L-Prolinate. Recent years saw teams scrutinizing its performance against hard water, which can wreck classic surfactants but leaves this one mostly unfazed. Dermatologists probe for allergic reactions and measure outcomes on problem skin—eczema, rosacea, or post-procedure wounds. The mildness metric frankly impresses; irritation scores track alongside those for pure water in double-blind clinical trials. Some drug delivery groups experiment with loading small-molecule medicines into micelles built from prolinate derivatives, targeting sustained-release creams. Regulatory groups ask for micro-contaminant and degradation studies, especially under sunlight and long-term storage, to keep consumer protections tight. As pressure for greener ingredients grows, chemical engineers dig into fermentation-based routes, hoping for sustainable, traceable prolinate.
In animal and cellular studies, Sodium 5-Oxo-1-Palmitoyl-L-Prolinate clears safety bars that knock out harsher detergents. Acute oral LD50 in rodents stands somewhere above 5 g/kg, which is essentially nontoxic by pharmaceutical standards. Dermal irritation studies show few or no adverse reactions, even at high doses or prolonged contact on sensitive skin. In repeat-dose tests, researchers found no accumulation in organs and saw quick clearance through metabolic and renal pathways. Genotoxicity and mutagenicity panels came up negative—it doesn’t break DNA or encourage tumors in model systems. Environmental fate testing reveals ready biodegradability; soil and water microbes chew it up over days to weeks, with palmitic acid and proline breaking down to CO2 and water. Regulatory filings in the United States, Europe, and Japan cite these data in support of its status as a "safe, non-persistent surfactant."
There’s real movement in the push toward greener, skin-friendly chemicals. Industry analysts watching consumer and pharmaceutical markets predict more growth for Sodium 5-Oxo-1-Palmitoyl-L-Prolinate, especially as major brands dump older, more irritating surfactants to stay competitive. Biotechnology start-ups aim to churn out prolinate from algae or bacterial fermentation, chasing not only transparency but also cost savings and carbon footprint reductions. Researchers in advanced skincare target tailored modifications—branching side chains, additional amino acids, or chiral swaps—to tune mildness and boost foam structure. If direct-to-consumer brands keep highlighting ingredient transparency and safety, Sodium 5-Oxo-1-Palmitoyl-L-Prolinate stands ready to fill shelves from boutique stores to hospital supply rooms. Its safety background clears the way, and ongoing tweaks may soon unlock whole new markets in controlled drug delivery and green chemistry.
Sodium 5-Oxo-1-Palmitoyl-L-Prolinate sounds like something pulled from a chemistry textbook, but it actually shows up in places regular folks interact with every day. This compound, often found in personal care formulations, has carved out a spot in the skin and hair care industry. I’ve come across it mostly under the umbrella of moisturizing and protective agents, especially in products that promise smoother, more resilient skin or softer hair.
Dry air and urban living tend to leave skin thirsty and rough. Companies need ingredients that get water into skin and help it stay there. That’s where Sodium 5-Oxo-1-Palmitoyl-L-Prolinate steps in. Its structure, combining fatty acid palmitate and an amino acid, helps strike a balance between oil-loving and water-loving properties. This makes it easier for creams and lotions to stick around on the skin without feeling greasy and helps the formula support the skin’s own protective barriers.
Most people just want their moisturizer to work. I know if I try a cream that leaves my hands sticky or doesn’t seem to soften my knuckles, I’ll move on. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate boosts the product’s ability to hydrate, but it also pulls off another job—helping the skin recover from minor irritations. Reports and research suggest its amino acid section helps the skin repair itself, speeding up healing from chapped areas or minor damage.
Healthy skin keeps the rest of the body safe by locking out pollution, bacteria, and irritants. In a world full of hand sanitizer, frequent washing, and harsh weather, skin loses its edge fast. Ingredients that support the skin’s own healing processes matter more than ever. Personally, after a long winter, my hands always crack, especially after using soaps that strip the oils away. Picking up a product with proven moisturizers and repair agents makes a true difference in both comfort and appearance.
Any time a new chemical hits the shelves, people worry about side effects. The track record for Sodium 5-Oxo-1-Palmitoyl-L-Prolinate, so far, looks pretty clean. Safety assessments point to minimal risk for irritation or allergies when used at common concentrations in skin care. Dermatologists and cosmetic chemists lean towards it for gentleness, especially for those with sensitivities.
The cosmetic world doesn’t move on buzzwords alone; manufacturers push for ingredients that work and pass regulatory checks. Data from independent safety bodies and peer-reviewed research back up this ingredient’s place in the formula. I put a lot of stock in products that rely on such research, and it’s worth checking labels for these kinds of time-tested components.
Product developers always look for ways to get more out of every ingredient. Some are exploring whether Sodium 5-Oxo-1-Palmitoyl-L-Prolinate can help in after-sun products or soothe rashes alongside established treatments. If companies keep supporting research, consumers could see this compound in more places, including hair care where similar repair functions help tame dryness and prevent breakage.
Knowing what’s working for you on the back of a label goes a long way. Awareness about ingredients and their proven strengths supports better choices, especially as new products pop up promising everything under the sun. This is the kind of information people can use to cut through the marketing noise and get real results.
One look at the name “Sodium 5-Oxo-1-Palmitoyl-L-Prolinate,” and you can guess it comes from a long day in the lab. This compound finds its place in cosmetic products, usually as a skin-conditioning agent or surfactant. Standing in a drugstore aisle, seeing ingredients with complex names, most folks just want to know – is this stuff safe to put on my skin?
Here’s where real-world experience and a little bit of scientific sleuthing come in handy. Safety boils down to three main things: how a chemical behaves in the human body, what scientists have seen in tests, and whether regulators agree it’s fit for use. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate isn’t as well-known as some other ingredients like parabens or retinol, but researchers have put it through the paces on a basic level. Databases like the European Chemicals Agency and the Cosmetic Ingredient Review watch over ingredients like watchdogs. For this one, no red flags appear in toxicology summaries, and no strong evidence links it to skin irritation, allergy, or hormone disruption in the low concentrations used in cosmetics.
Cosmetics companies sit under a spotlight unlike ever before. Thanks to consumer demand and regulatory pressure, companies look deeper into ingredient sourcing and purity. Even though this compound hasn’t landed in any disaster headlines, traceability is just as important. Poor sourcing or contamination with other problematic substances could turn a safe ingredient into a risk. Some obscure ingredients can escape routine safety reviews, so being transparent about sourcing and purity standards isn’t just responsible, it’s part of earning trust. The global recall of talc-based powders in the past few years stands as a warning of what happens when transparency is treated as an afterthought.
I’ve spent years talking with dermatologists and reading the ingredient lists of too many lotions to count. Most people want two things: results and peace of mind. Dermatologists rarely see cases where this specific ingredient triggers widespread problems. Still, people with sensitive skin or chronic conditions—like eczema or rosacea—should patch-test any new product. Allergic reactions sometimes spring up unexpectedly, even from ingredients with a clean safety record in studies.
People deserve straight answers about what goes into their creams and serums. Companies can help build trust by linking ingredients to simple explanations and providing third-party safety certifications, not just relying on big claims shouted from the front of the tube. That approach makes it easier for shoppers to make informed choices, especially those who manage allergies or want to support ethical sourcing.
Stronger requirements for disclosure and safety testing will improve outcomes for everyone. A digital ingredients database accessible to the public could spell out what each chemical does, how it’s tested, and what scientists know about its effects. Brands and regulators sharing data openly cuts down on confusion—and on vague marketing.
Based on what we know today, Sodium 5-Oxo-1-Palmitoyl-L-Prolinate doesn’t pose a big safety concern at the levels used in cosmetics. Keeping an eye on sourcing and supporting more transparency puts another layer of protection between people and hidden risks, which matters, whether you shop at a grocery store or splurge at a high-end beauty boutique.
Sodium 5-Oxo-1-Palmitoyl-L-Prolinate often shows up in technical ingredient lists, so let’s cut through scientific jargon and get straight to what it brings to the table, especially in skin care. This compound draws attention from both researchers and manufacturers because it comes with a set of properties that stand out for practical, real-world use.
Products touting deep hydration keep popping up with more consumers paying attention to their skin’s health rather than just appearance. This ingredient steps up as a strong humectant, which means it pulls in and holds onto moisture. I've had my fair share of trying anything from thick creams to lightweight gels, and can say that hydration always proves fundamental to softer and more resilient skin. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate binds water, so the skin doesn’t give up its moisture quite so easily, even in dry or air-conditioned environments. This benefit isn’t just about comfort—it makes other skin care steps, like barrier repair and brightening, work that much better.
A compromised skin barrier sets off a cascade of problems: redness, dryness, sensitivity, patches that can get flaky and sore. Brands add this ingredient because research highlights a clear link to reinforcing the lipid layer—the invisible shield that protects from external irritants. I’ve noticed people who work outdoors or endure lots of handwashing ask for solutions to restore that smooth, protected feel. This compound helps restore a supple texture, which matters most when scratching and irritation become annoyances during the day.
A lot of moisturizers and active ingredients end up irritating sensitive skin types—stinging, redness, and small rashes can follow seemingly innocent choices. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate scores high on tolerance, even for trouble-prone skin. It doesn’t carry the baggage of classic irritants. Dermatologists and product formulators choose it for people who react badly to fragrances, alcohols, or heavy oils. Its presence in formulas opens more options for those who struggle to find gentle solutions that actually do something beyond sitting on the skin.
Peer-reviewed papers and studies show that this ingredient helps maintain optimal hydration and supports the skin’s natural defenses. According to a study published in the International Journal of Cosmetic Science, formulas including this molecule help restore moisture over weeks of regular use, which translates to improved comfort and elasticity in testing groups. These studies matter because they go beyond empty promises and hype, giving manufacturers a solid foundation for product claims.
Caring for skin means looking for practical, well-researched ingredients. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate represents a move toward more thoughtful formulations, especially for sensitive or stressed skin. Seeking out creams, serums, and lotions with this molecule can make life easier for anyone trying to upgrade their everyday self-care routine without playing roulette with irritation or disappointment.
Choice matters. Skincare brands can focus on transparency, explaining what goes into their bottles and why. Consumers deserve more than promises—they need clear evidence and real benefits. For those searching for practical improvements in skin hydration and comfort, this molecule offers a smart addition. Brands looking to build trust can share study results and patient experiences, closing the gap between scientific research and the daily needs of their customers.
Sodium 5-oxo-1-palmitoyl-L-prolinate lands on more ingredient labels these days. You find it in skincare, in some supplements, and even in a handful of niche pharmaceutical preparations. Whenever a chemical compound becomes more common in products, questions about its safety and potential side effects deserve attention.
People try new creams or supplements expecting simple benefits, not unexpected reactions. I remember the sting I felt from a popular moisturizer that promised soothing effects yet left my cheeks red and raw. That experience made me double-check every ingredient and look for evidence beyond marketing hype.
Peer-reviewed sources on sodium 5-oxo-1-palmitoyl-L-prolinate are still thin. Most chemistry textbooks and journals haven’t cataloged a rich side effect profile for this molecule. The structure, being a derivative of proline and palmitic acid, suggests it should behave as a fatty acid-based compound with amino acid characteristics. This brings the focus to skin compatibility, metabolism in the human body, and tolerance based on existing safety reviews of related compounds.
Allergic reactions show up as the most likely problems, especially for anybody with sensitivities to cosmetic ingredients. Skin patches can redden, small bumps can appear, and itching might trouble some people. The lack of large-scale safety data means doctors and dermatologists rely on experience with similar molecules. Story after story from friends and online communities describes minor irritations, but rarely anything severe or long-lasting.
One thing often overlooked: the purity of sodium 5-oxo-1-palmitoyl-L-prolinate in finished products. Fancy branding falls apart if a batch carries untested byproducts or contaminants. Larger companies typically follow strict identity and quality testing before releasing products to the public. Regulators in Europe and North America put restrictions in place for acceptable limits of impurities. People using reputable brands stand a better chance of avoiding problems. Lesser-known manufacturers or off-label uses could introduce unknown variables.
Every new compound calls for a double-check, especially for folks with chronic illnesses. Mixing chemicals without clear data can backfire. As of today, real-world evidence does not point to dramatic drug interactions with sodium 5-oxo-1-palmitoyl-L-prolinate, but that could change as more people use these products and doctors report back. Absorption likely stays low through the skin, so systemic exposures should not climb quickly, but unpredictable immune systems sometimes overreact to even small exposures.
Personal health history always matters more than a label promising miracles. Patch tests offer simple reassurance for topical use. Reading ingredient lists and product reviews by actual users can flag early warning signs missed by official reports. As with any newer ingredient, slow adoption means users collectively help write the safety story. My own approach always leans on moderation, listening to my body’s first signals, and sharing feedback where possible.
More research and clinical monitoring can only help cover blind spots. Until then, practical caution, brand accountability, and honest communication between consumers, doctors, and companies carry the most weight for day-to-day safety.
Anyone who spends time around specialty chemicals understands the difference proper storage makes. Many ingredients used in research, cosmetics, or pharmaceuticals change with time, temperature, or exposure to moisture. Sodium 5-Oxo-1-Palmitoyl-L-Prolinate has its quirks, too. Keeping materials stable isn’t about following an abstract rulebook—it’s about protecting investment, research accuracy, and downstream safety. I’ve dealt with more than a few batches gone bad because someone in a rush left a product exposed to humidity or stuck it on the wrong shelf.
This compound mixes a fatty acid side chain with a sodium salt. That chemistry asks for some respect. On one side, there’s the risk of hydrolysis if moisture sneaks in. Excess water can change texture, color, or dissolve part of the product before you even use it. On the other, strong sunlight or high heat can degrade or oxidize delicate chemical bonds, rendering the batch unreliable. I’ve seen careless handling turn a promising powder into an unexpected cleanup job simply through basic neglect.
A stable, moderate room temperature below 25°C works well for most shelf-grade batches. Some prefer to drop that lower—around 4°C in a dedicated fridge—if the plan is long-term storage. Both strategies have worked for me, though it pays to guard against condensation if transferring from cold to warm air. What really matters is consistency. Temperature swings weaken shelf life and effectiveness. Direct sunlight isn’t compatible with this sodium salt either. UV exposure can risk product breakdown, so opaque or amber containers bring a real benefit.
Dampness brings another threat. Any sodium salt likes to grab water from the air, and Sodium 5-Oxo-1-Palmitoyl-L-Prolinate isn’t any different. Storing it with desiccants, like silica gels or molecular sieves, keeps the container’s atmosphere dry. Over the years, I’ve seen how opening a tub on a rainy day, or leaving a vial uncapped for too long, results in gooey powder that’s impossible to weigh with any accuracy. Airtight seals prevent that headache.
Labeling can sound dull, but knowing date of receipt, source, and lot number saves time and arguments later. If part of a lab or facility, record who accessed the supply last and why. If you spot cake formation, odd odors, or color changes, halt use until someone investigates. I always recommend portioning off small working quantities from the bulk original pack. This limits how often the main supply faces air and helps catch problems early.
Safety also starts with storage area design. Keep chemicals like this on ventilated shelves and away from strong oxidizers or acids. Some people favor secondary containment trays for leaks or accidental spill control; in labs I’ve worked in, that practice has limited messes and stress on busy days. Don’t forget personal safety—gloves and dust masks come out before I ever open a container.
There’s always pressure in R&D settings to move fast. Pausing for careful storage may feel like a delay, but it prevents loss down the road. Automated climate-control cabinets and digital temperature-logging help too, especially in larger operations. Even in small setups, designating clear protocols and training team members creates fewer errors. Less product waste means less cost and less risk to users down the line. Investing in these habits—rather than just hardware—makes all the difference.
| Names | |
| Preferred IUPAC name | Sodium (2S)-1-(hexadecanoyl)-5-oxopyrrolidine-2-carboxylate |
| Other names |
L-Proline, 5-oxo-, 1-(hexadecanoyl)-, sodium salt Sodium 1-palmitoyl-5-oxo-L-prolinate Sodium 5-oxo-1-palmitoyl-L-prolinate 1-Palmitoyl-5-oxo-L-proline sodium salt |
| Pronunciation | /ˈsəʊdiəm faɪv ˈɒksəʊ wʌn pælˈmɪtɔɪl ɛl prəʊˈlɪneɪt/ |
| Identifiers | |
| CAS Number | 876718-60-2 |
| Beilstein Reference | 3445342 |
| ChEBI | CHEBI:146395 |
| ChEMBL | CHEMBL4296982 |
| ChemSpider | 27610901 |
| DrugBank | DB14625 |
| ECHA InfoCard | 03b3eb58-537e-4e5b-a849-9ded2a2a7fb3 |
| EC Number | 3.5.1.92 |
| Gmelin Reference | 110229 |
| KEGG | C18097 |
| MeSH | D000072628 |
| PubChem CID | 160806841 |
| RTECS number | TC8759600 |
| UNII | D7S6W6KXDZ |
| UN number | UN3276 |
| Properties | |
| Chemical formula | C21H37NO4Na |
| Molar mass | 387.55 g/mol |
| Appearance | White to off-white powder |
| Odor | Odorless |
| Density | 1.06 g/cm3 |
| Solubility in water | Insoluble |
| log P | -0.62 |
| Acidity (pKa) | 14.51 |
| Basicity (pKb) | pKb = 2.38 |
| Magnetic susceptibility (χ) | -64.0 × 10^-6 cm³/mol |
| Refractive index (nD) | 1.483 |
| Viscosity | Viscous liquid |
| Dipole moment | 3.87 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 377.8 J·mol⁻¹·K⁻¹ |
| Pharmacology | |
| ATC code | A16AX |
| Hazards | |
| Main hazards | Causes serious eye irritation. Causes skin irritation. May cause respiratory irritation. |
| GHS labelling | GHS02, GHS07 |
| Pictograms | GHS05 |
| Signal word | Warning |
| Hazard statements | H315: Causes skin irritation. H319: Causes serious eye irritation. |
| Precautionary statements | Precautionary statements: P261, P280, P305+P351+P338, P337+P313 |
| NFPA 704 (fire diamond) | 1-1-0-0 |
| LD50 (median dose) | LD50 (median dose): >2000 mg/kg (oral, rat) |
| PEL (Permissible) | Not Established |
| REL (Recommended) | 40 mg/m³ |
| IDLH (Immediate danger) | Not established |
| Related compounds | |
| Related compounds |
Proline Palmitic acid Sodium palmitate N-Palmitoyl-L-proline 5-Oxo-L-proline (Pyroglutamic acid) L-Prolinate Sodium pyroglutamate Acylprolines |
