Product Name: (S)-Pyrrolidine-2-Carboxamide
Synonyms: L-Prolinamide, (S)-Prolinamide
CAS Number: 3880-99-1
Recommended Use: Laboratory chemical, pharmaceutical ingredient, synthesis intermediate
Supplier Name: Refer to primary manufacturer or distributor
Contact Information: Refer to Safety Office or emergency response number
Emergency Phone: Local emergency services or poison control center
Classification: Not classified as hazardous according to GHS criteria
Label Elements: No pictogram or signal word required
Hazard Statements: May cause mild skin or eye irritation in sensitive individuals
Precautionary Statements: Avoid prolonged skin contact, do not breathe dust, wash hands after handling
Routes of Exposure: Inhalation, skin or eye contact, ingestion
Symptoms: Redness, slight irritation of eyes or skin, mild respiratory discomfort from dust
Other Hazards: No known significant effects or critical hazards under normal conditions
Chemical Name: (S)-Pyrrolidine-2-Carboxamide
CAS Number: 3880-99-1
EC Number: 223-405-9
Purity: Above 98% (common for lab and industrial preparations)
Impurities: No major impurities considered hazardous at relevant concentrations
Formula: C5H10N2O
Molecular Weight: 114.15 g/mol
General Advice: Seek medical attention if symptoms persist or after significant exposure
Inhalation: Remove to fresh air, monitor breathing, seek medical help if symptoms develop
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek medical attention
Symptoms/Effects: Expect mild irritation at most; persistent symptoms require medical review
Advice for Physicians: Treat based on observed symptoms, no specific antidote known
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Unsuitable Extinguishing Media: Strong direct water jet can spread combustible dust
Hazards from Combustion: Possible release of nitrogen oxides (NOx), carbon monoxide/co2, other toxic fumes
Protective Equipment for Firefighters: Self-contained breathing apparatus, protective clothing, gloves
Special Procedures: Move containers from area if safe, cool exposed containers with water spray
Specific Hazards: Powder can form explosive mixtures with air under certain conditions, avoid dust buildup
Personal Precautions: Avoid breathing dust, ventilate area, wear appropriate protective equipment
Environmental Precautions: Prevent entry into drains, waterways, or soil
Containment Methods: Sweep up, avoid creating dust, place in a suitable waste container
Cleanup Procedures: Wash area with plenty of water after removal of material
Disposal: Dispose of according to local, state, and federal regulations
Protective Measures: Wear gloves, eye and face protection, use dust mask if handling large bulk
Handling: Minimize airborne dust, avoid contact with skin and eyes, keep container tightly closed
Storage: Store in dry, cool, well-ventilated area, keep away from incompatible substances like strong oxidizers
Storage Conditions: Ambient room temperature, away from heat and direct sunlight, segregate from food and beverages
Packing Materials: Use original containers or containers made from compatible materials like high-density polyethylene
Occupational Exposure Limits: No established exposure limit for this material
Engineering Controls: Use local exhaust ventilation or process enclosure to minimize dust
Personal Protective Equipment: Nitrile gloves, safety goggles, lab coat
Respiratory Protection: Dust mask or particulate respirator if exposure to powder occurs
Eye Protection: Safety glasses with side shields
Hand Protection: Protective gloves suitable for chemical handling
Hygiene Measures: Wash hands before breaks and after handling, do not eat or drink in work area
Appearance: White to off-white crystalline powder
Odor: Characteristic, faint odor or odorless
Odor Threshold: Not determined
pH: Not applicable (solid)
Melting Point/Range: 122-127°C
Boiling Point: Decomposes before boiling
Flash Point: Not relevant for solids
Evaporation Rate: Not applicable
Flammability: Not easily flammable as solid, avoid accumulation of dust
Explosive Properties: Dust may pose risk in air in confined spaces
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not applicable
Solubility: Soluble in water, ethanol, other polar solvents
Partition Coefficient (log Kow): Not available
Auto-ignition Temperature: Not established
Decomposition Temperature: Above 150°C, releases nitrogen-containing gases
Viscosity: Not applicable (solid)
Stability: Stable under standard handling and storage conditions
Reactivity: Not considered reactive under normal conditions
Hazardous Reactions: Contact with strong oxidizers may cause exothermic reactions
Conditions to Avoid: Excessive heat, direct sunlight, generation of dust
Incompatible Materials: Strong oxidizing agents, acids, bases
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide
Acute Toxicity: Data limited, not considered highly toxic based on available information
Oral LD50: Above 2000 mg/kg (rat, estimated)
Skin Corrosion/Irritation: May cause mild irritation in sensitive individuals
Serious Eye Damage/Irritation: Dust can cause temporary discomfort
Respiratory Sensitization: Exposure to dust may cause mild irritation
Skin Sensitization: No known sensitizing effects
Germ Cell Mutagenicity: No data available
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No information available
Repeated Dose Toxicity: Not expected at occupational exposure levels
Specific Target Organ Toxicity: No known effects at typical exposure levels
Ecotoxicity: Not expected to be harmful to aquatic or terrestrial organisms in small releases
Persistence and Degradability: Readily biodegradable under environmental conditions
Bioaccumulation Potential: Low, based on structure and physicochemical properties
Mobility in Soil: Expected to have moderate mobility when dissolved in water
Other Adverse Effects: Not expected under normal circumstances, avoid large-scale environmental release
Waste Disposal: Collect and place in labeled containers for disposal at approved facility
Contaminated Packaging: Decontaminate if possible or dispose as hazardous chemical waste
Disposal Methods: Incinerate or dispose of in accordance with local, regional, and national regulations
Precautions: Avoid uncontrolled releases into sewage, waterways, or soil
UN Number: Not regulated as dangerous goods
Proper Shipping Name: (S)-Pyrrolidine-2-Carboxamide or chemical, solid, not otherwise specified
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions for Transport: Secure containers, avoid moisture and dust release during transport
US TSCA Status: Listed or exempt
EU REACH Registration: Exempt as intermediate or not listed due to volume
California Proposition 65: Not listed
SARA 313: Not subject to reporting
Canadian DSL/NDSL: Consult supplier
Additional Regulations: All applicable local, regional, national, and international regulations apply for storage, use, and disposal
