Substance Name: (R)-(+)-N-Boc-3-Pyrrolidinol
Chemical Formula: C9H17NO3
CAS Number: 115837-24-6
Manufacturer: Supplier or producer details available from chemical distributor
Recommended Use: Laboratory research, chemical synthesis, pharmaceutical intermediate
Emergency Contact: Chemtrec (United States): 1-800-424-9300
Classification: Not classified as hazardous under GHS or OSHA standards, but take all precautions normally used for laboratory chemicals
Signal Word: None
Hazard Statements: May cause skin or eye irritation, dust may be irritating to respiratory tract, not enough data for chronic effects
Pictograms: Not required
Precautionary Statements: Avoid contact with eyes, skin, and clothing; use in well-ventilated area; do not eat, drink, or smoke when using; wash hands after handling
Chemical Name: (R)-(+)-N-Boc-3-Pyrrolidinol
Synonyms: tert-Butyl (R)-3-hydroxypyrrolidine-1-carboxylate
Purity: 97-99% (by typical supplier specifications)
Impurities: Not specified for routine laboratory use
Additives: None intended for final substance as supplied
Inhalation: Move person to fresh air, support breathing, seek medical attention if symptoms develop or persist
Skin Contact: Remove contaminated clothing, wash affected area with copious amounts of water for at least 15 minutes, get medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do; seek medical care for any pain or redness
Ingestion: Rinse mouth with water if conscious, do not induce vomiting, consult a physician immediately
Important Notes: Show this sheet to medical personnel if medical care is needed
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Special Hazards: May emit toxic fumes of carbon oxides and nitrogen oxides under fire conditions
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical protective clothing
Precautions: Approach fire from upwind, use standard firefighting techniques for organic solids, avoid inhalation of combustion gases
Personal Precautions: Use personal protection—gloves, goggles, lab coat, avoid dust formation
Environmental Precautions: Prevent release to soil, sewers, surface water
Methods for Cleaning Up: Sweep or scoop up material into suitable containers for disposal, ventilate area, wash spill site after material pick up, collect residue with damp cloth or absorbent material
Safe Handling: Use in chemical fume hood or ventilated workspace, avoid inhalation and contact with skin or eyes, wear all recommended PPE, keep containers closed
Storage Requirements: Store in cool, dry location, protect from light and moisture, keep away from incompatible chemicals like oxidizers and acids, label clearly with hazard warnings
Engineering Controls: Chemical fume hood, general laboratory ventilation
Personal Protective Equipment: Nitrile gloves, splash-proof goggles, lab coat
Respiratory Protection: Use NIOSH-approved respiratory protection if dust or aerosols are generated and ventilation is inadequate
Hygiene Measures: Wash hands after handling, remove contaminated clothing immediately, do not eat or drink in chemical storage or handling areas
Exposure Limits: No OSHA, ACGIH, or local regulatory exposure limits established for this specific compound
Appearance: White to off-white crystalline powder
Odor: Not significant
Melting Point: 54-58°C (supplier-reported)
Molecular Weight: 187.24 g/mol
Solubility: Soluble in polar organic solvents, slightly soluble in water
pH: Not available
Boiling Point: Data not available or decomposes
Vapor Pressure: Not available
Partition Coefficient: Not determined
Flash Point: Not established (solid, low volatility)
Density: Not measured directly; estimated close to 1.1–1.2 g/cm³ (based on structure)
Reactivity: Stable under recommended storage and handling conditions
Chemical Stability: Stable at room temperature if kept dry and protected from air and light
Possibility of Hazardous Reactions: No hazardous polymerization; reacts with strong oxidizers, acids
Conditions to Avoid: Exposure to heat, flame, strong acids and bases, oxidizing materials, prolonged air or moisture
Decomposition Products: Carbon oxides, nitrogen oxides, tertiary butyl alcohol on breakdown
Acute Toxicity: Not thoroughly studied for humans; use precautions typical for laboratory chemicals
Skin and Eye Irritation: Expected to be irritating to skin and eyes by analogy to similar chemical structures
Respiratory Sensitization: Inhalation of dust may cause respiratory irritation
Carcinogenicity: No data, not listed by IARC, NTP, OSHA
Mutagenicity / Reproductive Toxicity: No data reported
Other Risks: Prolonged or repeated exposure may cause symptoms of irritation or allergic reaction in susceptible individuals
LD50 (oral, rat): Not experimentally determined
Aquatic Toxicity: No specific data available for this compound
Persistence and Degradability: Not persistent under normal environmental conditions based on chemical nature; likely to degrade slowly in the environment
Bioaccumulative Potential: No measured data, but low potential expected based on solubility and chemical structure
Mobility in Soil: Limited mobility expected based on structure
Other Adverse Effects: Avoid release to the environment due to lack of ecological hazard data; use all recommended spill controls to prevent entry into waterways
Waste Treatment Methods: Collect and dispose of as hazardous organic laboratory waste
Recommended Disposal: Send to licensed chemical disposal facility, comply with all local, state, and federal regulations
Container Disposal: Triple-rinse containers and puncture once empty; dispose as hazardous waste
Precautions: Do not release to drains, surface water, or environment; label all waste containers clearly
UN Number: Not regulated as dangerous for transport under DOT, IATA, IMDG guidelines
UN Proper Shipping Name: Not regulated; ship as non-hazardous chemical
Transport Hazard Class: Not assigned
Packing Group: Not assigned
Marine Pollutant: Not classified as marine pollutant
Special Precautions: Handle as laboratory chemical, ensure integrity of packages, ship with appropriate hazard communication if mixed with solvents or other hazards
TSCA Status: Not listed for commercial use on TSCA inventory; for research only
SARA Title III: Not subject to reporting under Sections 302, 304, or 313
California Proposition 65: Not listed
REACH Status (Europe): May require notification for import or manufacture above threshold limits; verify with supplier
Other Country Regulations: Check applicable regulations in country of use
Labeling Requirements: Apply laboratory chemical labeling guidelines; include identity, hazard class, key precautions
