Product Name: (R)-3-Boc-Aminopiperidine
CAS Number: 1191375-48-2
Synonyms: (R)-tert-Butyl 3-aminopiperidine-1-carboxylate
Recommended Use: Laboratory chemicals, synthesis of pharmaceuticals and intermediates
Manufacturer: Reference supplier or organizational chemical inventory
Contact Information: See supplier or institution emergency contacts
Emergency Phone Number: Refer to in-house HSE or local poison control
GHS Classification: Skin irritation, Eye irritation, Acute toxicity (oral)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed
Pictograms: Exclamation mark
Precautionary Statements: Wear gloves/protective clothing, avoid breathing dust, wash hands thoroughly after handling
Health Hazards: Irritation to skin, eyes, and respiratory system
Environmental Hazards: Harmful to aquatic life in larger quantities
Chemical Identity: (R)-3-Boc-Aminopiperidine
CAS Number: 1191375-48-2
Concentration: ≥98% (by supplier specification)
Impurities: Typically below 1%; identity supplied by manufacturer if available
Hazardous Components: No additional hazardous ingredients expected at notification concentration
Inhalation: Move to fresh air, monitor breathing, seek medical advice if discomfort continues
Skin Contact: Remove contaminated clothing, wash affected skin with soap and plenty of water, seek medical help if irritation persists
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if present, keep eyelids apart, get medical advice if irritation develops
Ingestion: Rinse mouth thoroughly, drink water if conscious, avoid inducing vomiting, seek immediate medical attention
Important Symptoms: Redness, irritation, nausea, discomfort, headache possible with exposure
Advice to Doctor: Treat symptomatically based on clinical assessment
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray (for large fires)
Unsuitable Extinguishing Media: High-pressure water jets can spread chemical
Specific Hazards from Fire: May produce toxic gases such as carbon oxides, nitrogen oxides under combustion
Protective Equipment: Firefighters should use self-contained breathing apparatus, full protective gear
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, nitrogen oxides, other unidentified toxic compounds
Advice for Firefighters: Stay upwind to avoid exposure to fumes; cool containers with water spray
Personal Precautions: Ventilate area, avoid dust formation, ensure use of gloves, goggles, mask, and lab coat for any cleanup
Environmental Precautions: Prevent spillage from entering drains, surface water, or soil
Spill Cleanup Methods: Sweep up carefully, avoid generating dust, collect in labeled container, wash area with soap and water, ventilate well
Handling of Waste: Place spilled material and contaminated items in a sealed, properly labeled waste container for disposal according to local regulations
Precautions for Safe Handling: Use only in well-ventilated areas, avoid contact with skin, eyes, clothing, or inhalation of dust, avoid eating or drinking in lab space, wash hands thoroughly after handling
Conditions for Safe Storage: Store in tightly sealed original container, keep in cool, dry location, away from direct sunlight and incompatible materials like acid anhydrides and strong oxidizers
Storage Class: Chemical storage—non-flammable solid, preferably with controlled temperature (15-25°C)
Incompatible Products: Strong oxidizing agents, strong acids and bases, moisture
Specific End Uses: Reserved for research and industrial applications only
Control Parameters: No specific occupational exposure limit value established (consult national guidelines if available)
Engineering Controls: Use fume hood, chemical-resistant bench tops, local exhaust ventilation systems
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile or neoprene), full-length lab coat, respiratory protection in case of insufficient ventilation or dust
Hygiene Measures: Remove and wash contaminated clothing; maintain proper workplace cleanliness; keep away from food and beverages
Physical State: White to off-white crystalline solid
Molecular Formula: C10H20N2O2
Molecular Weight: 200.28 g/mol
Melting Point: 91–95°C (approximate/typical supplier data)
Boiling Point: Not available
Solubility: Soluble in organic solvents (DMF, DMSO, methanol), limited in water
Odor: Faint, characteristic amine
pH: Not applicable (solid)
Density: ~1.1–1.2 g/cm³
Vapor Pressure: Not available
Flash Point: Not available
Partition Coefficient: Not available
Evaporation Rate: Not available
Auto-Ignition Temperature: Not determined
Decomposition Temperature: Data not provided, decomposes above melting point
Chemical Stability: Stable under standard laboratory conditions, avoid heat and humidity
Reactivity: No hazardous polymerization or rapid reactivity expected under normal use
Conditions to Avoid: Moisture exposure, high temperature, open flames, strong oxidizing or reducing environments
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, other volatile organic compounds
Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Oral exposure may cause pain, headache, nausea; LD50 not established
Skin Corrosion/Irritation: Possible redness and irritation on contact
Eye Damage/Irritation: May cause moderate to severe irritation with redness
Respiratory Sensitization: Cough, shortness of breath, sore throat with prolonged exposure to dust
Germ Cell Mutagenicity: No data available
Carcinogenicity: Listed as non-carcinogenic by major agencies
Reproductive Toxicity: No data
Long-term Effects: None expected under proper laboratory use and containment
Ecotoxicity: Harmful to aquatic organisms in bulk or concentrated spill
Persistence/Degradability: Data limited; not expected to degrade rapidly in environment
Bioaccumulative Potential: No evidence for bioaccumulation in aquatic or terrestrial organisms at laboratory use levels
Mobility in Soil: No reliable mobility data
Other Effects: Avoid direct release to natural waterways, channels, or drains to minimize risk
Waste Disposal: Dispose through licensed chemical waste handler in compliance with local and national regulations
Waste Containers: Use leak-proof, labeled, segregated containers; separate organic waste from inorganics
Contaminated Packaging: Treat as hazardous waste, dispose of with same procedures as for unused product
Do Not: Discharge into sewer systems, landfill, or environment unless specifically permitted by appropriate authorities
UN Number: Not regulated for transport as per current data
UN Proper Shipping Name: Chemical, n.o.s. (not otherwise specified)
Transport Hazard Class: Not classified as hazardous for transport
Packing Group: Not assigned
Environmental Hazards: Not specifically regulated, but precaution against release
Special Precautions: Package in secondary containment if possible; limit movement in public spaces
TSCA (US): Check supplier/SDS for listing status
REACH (EU): Not registered; exempt when used for research purposes
Other Regulations: Subject to workplace safety, chemical handling, and waste management rules
International Inventories: Not listed in most chemical inventories; custom chemical, typically for research
Labelling Requirements: Show product name, hazard pictograms, risk and safety statements on primary container
