Product Name: Pyrrole
Chemical formula: C4H5N
CAS Number: 109-97-7
Synonyms: Azole, 1H-Pyrrole, Pyrrol
Manufacturer: Provided by supplier or distributor, often found on packaging label
Recommended Use: Intermediate for pharmaceuticals, chemical research, organic synthesis
Emergency Phone: Check manufacturer resources or local regulations for emergency contact
Classification: Flammable liquid, Acute toxicity (oral), Skin irritant, Eye irritant, Specific target organ toxicity (single exposure)
Hazard Statements: Highly flammable liquid and vapor, Harmful if swallowed, Causes skin and eye irritation, May cause respiratory irritation
Signal Word: Danger
Pictograms: Flame, Exclamation mark
Precautionary Statements: Keep away from heat or sparks, Wear protective gloves, Wash hands thoroughly after handling, Use only outdoors or in a well-ventilated area, Do not eat, drink, or smoke when handling
Chemical Name: Pyrrole
Concentration: ≥98% (as supplied in most reagents)
Impurities: Trace water, possibly minor secondary amines, manufacturer dependent
Hazardous Components: None in significant concentrations aside from pyrrole itself
Additives: None intentionally added in most chemical-grade samples
Inhalation: Move individual to fresh air immediately, loosen tight clothing, keep at rest, seek medical advice if symptoms continue such as shortness of breath or irritative cough
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with soap and water, seek medical help if skin irritation persists or blistering develops
Eye Contact: Gently rinse eyes with water for at least 15 minutes, remove contact lenses if present, get medical attention in case of burning, redness, or persistent pain
Ingestion: Rinse mouth thoroughly with water, do not induce vomiting, seek immediate medical attention, provide product label to responders
Notes for Doctors: Treat symptomatically. There is no specific antidote. Monitor for respiratory distress and possible delayed pulmonary effects due to solvent properties
Suitable Extinguishing Media: Dry chemical, foam, CO2, or water spray (avoid high-pressure water jets that may spread fire)
Specific Hazards: Vapors can form explosive mixtures with air, fire may produce nitrogen oxides, carbon monoxide, irritant gases
Protective Equipment: Firefighters should wear self-contained breathing apparatus with full face mask, and suitable protective clothing
Special Procedures: Approach from upwind, use water spray to cool unopened containers nearby, contain contaminated runoff
Explosion Data: Vapors heavier than air, risk of flashback possible, containers may explode under fire conditions
Personal Precautions: Ventilate area, remove all ignition sources, wear chemical splash goggles, nitrile gloves, lab coat or equivalent, use respirator if exposure risk is high
Environmental Precautions: Prevent entry into drains, sewers, watercourses or soil, use absorbent material (sand, earth) for spill containment
Clean-Up Methods: Collect spillage into waste containers for disposal, flush area with water once collection is complete, avoid producing aerosols, dispose of contaminated items as hazardous waste
Decontamination: Wash area thoroughly using detergent and water, ventilate area after cleanup
Safe Handling: Use only in well-ventilated areas, avoid contact with eyes and skin, avoid inhaling vapor or mist, keep away from heat and open flame, never use near sources of ignition, keep containers tightly sealed
Storage Conditions: Store in tightly closed amber glass container, keep cool and dry, protect from light, segregate from oxidizers, acids, and alkalis
Incompatible Materials: Strong oxidizing agents, acids, acid chlorides, anhydrides
Hygiene Considerations: Wash hands after use, remove contaminated clothing and clean before reuse, no eating, drinking, or smoking in work area
Occupational Exposure Limits: No specific OSHA, ACGIH, or NIOSH limits established for pyrrole; use engineering controls and common sense
Engineering Controls: Use fume hood for handling large or volatile amounts, ensure adequate ventilation, use explosion-proof electrical installations in hazardous areas
Eye Protection: Safety goggles with side-shields
Skin Protection: Chemical-resistant gloves (nitrile or neoprene recommended), laboratory coat, closed footwear
Respiratory Protection: Use organic vapor cartridge respirator if risk of inhalation, especially in poorly ventilated settings
Other Controls: Emergency eyewash station and safety shower nearby in all locations handling open containers
Appearance: Colorless to pale yellow volatile liquid with distinct, pungent odor
Odor: Sweet, peculiar odor often described as ether-like, noticeable at low concentrations
Boiling Point: 129-131°C (264-268°F)
Melting Point: -23°C (-9°F)
Flash Point: 31°C (88°F), closed cup
Flammability: Flammable liquid, vapor forms explosive mixtures with air
Vapor Pressure: 10 mmHg at 25°C
Vapor Density: 2.2 (air = 1)
Solubility: Slightly soluble in water, miscible with ethanol and ether
Density: 0.967 g/cm³ at 20°C
pH: Not applicable (neutral compound)
Partition Coefficient: logP ~0.8
Chemical Stability: Stable under recommended conditions, sensitive to light and air
Conditions to Avoid: Heat, direct sunlight, open flame, sparks, static discharge
Materials to Avoid: Strong oxidizers, acids, acid chlorides
Hazardous Reactions: May polymerize or decompose on heating, oxidizing conditions accelerate breakdown
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, possible toxic organic vapors
Polymerization: No hazardous polymerization under normal storage, risk rises with peroxides or strong acids
Acute Toxicity: Oral LD50 (rat): 475 mg/kg, Inhalation and dermal toxicity data limited
Skin Corrosion/Irritation: Causes irritation to skin, may cause redness, inflammation after contact
Eye Damage/Irritation: Eye irritant, can cause stinging, redness, watering
Respiratory Sensitization: May irritate respiratory tract on inhalation, causing coughing, throat discomfort
Other Effects: CNS depression at high doses (dizziness, headache), possible liver and kidney effects with heavy or repeated exposure
Chronic Effects: Data limited, occupational exposure not widely studied, potential for cumulative effects on nervous system still debated
Carcinogenicity: Not listed as carcinogen by NTP, IARC, OSHA
Aquatic Toxicity: Moderately toxic to fish and aquatic life, limited decomposition in water, risk of bioaccumulation low
Mobility in Soil: Reasonably mobile, may leach into groundwater at spill sites
Persistence and Degradability: Degrades slowly under environmental conditions, volatile so rapid evaporation possible
Bioaccumulation Potential: Low based on structure and physical properties
Other Risks: Release may impact local watercourses, proper containment is important to minimize harm
Disposal Methods: Incinerate in a chemical incinerator with afterburner and scrubber, do not dispose in sewer or household waste stream
Container Disposal: Triple rinse empty containers, puncture and offer for hazardous waste disposal as required by regulations
Precautions: Consult local, national, regional regulations and seek licensed hazardous waste disposal service
Contaminated Packaging: Dispose of as hazardous waste, do not recycle or reuse containers for non-chemical storage
UN Number: UN2071
UN Proper Shipping Name: Pyrrole
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Labeling Requirements: Flammable liquid label
Transport Precautions: Keep containers upright and tightly sealed, avoid violent impacts, clearly mark shipping documents and containers
Special Rules: Not permitted on aircraft in passenger or cargo without declaration, follow IMDG and IATA guidelines closely
TSCA Status: Listed in the United States Toxic Substances Control Act inventory
Safety Reporting: Subject to safety reporting under SARA Title III/EPCRA Section 313 for certain uses
Other Regulations: Not regulated under US Clean Air Act or Clean Water Act, not a controlled substance in most countries, local chemical handling and storage rules may apply
Workplace Labelling: Requires clear labeling per OSHA’s Hazard Communication Standard, MSDS/SDS access for all users
EU Classification: F: Highly Flammable, Xi: Irritant; Risk Phrases: R11 (flammable), R36/37/38 (irritant), S16 (keep away from sources of ignition)
International Inventories: Included in EINECS (Europe), DSL (Canada), ENCS (Japan) under relevant entries
