Product Name: Pyrazinylethanethiol
Chemical Formula: C6H8N2S
CAS Number: 32880-74-1
Synonyms: 2-(2-Pyrazinyl)ethanethiol, 2-pyrazinylethyl mercaptan
Recommended Use: Research and industrial synthesis
Supplier Details: Contact your local distributor or manufacturer for current address and phone information
Emergency Contact: Refer to national or regional poison control centers; supplier emergency lines available on request
Classification: Flammable liquid, acute toxicity (oral, dermal), skin/eye irritant, respiratory sensitizer
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor, toxic if swallowed, contact may cause severe skin and eye irritation, inhalation can trigger allergic reactions or respiratory discomfort
Pictograms: Flame, skull and crossbones, exclamation mark
Potential Health Effects: Short exposures make skin sting, eyes water; accidental swallowing can cause nausea, vomiting, dizziness, headaches; sensitive people might feel tightness in chest or allergic effects if inhaled over a period
Environmental Risks: Toxic to aquatic life; spills may disrupt local water sources
Chemical Name: 2-(2-Pyrazinyl)ethanethiol
Concentration: 97-100%
Impurities: Minor thiol derivatives (< 1%), check with supplier for full breakdown
Stabilizers/Additives: None reported in general-use formulations
Inhalation: Remove the exposed person to fresh air, keep comfortable, administer oxygen if breathing is difficult, consult a doctor
Skin Contact: Rinse thoroughly with plenty of water, remove contaminated clothing, seek medical attention if redness, blistering, or pain develops
Eye Contact: Rinse under running water for several minutes, lift eyelids to flush thoroughly, seek medical advice to check for corneal injury
Ingestion: Do not induce vomiting; rinse mouth with water, call poison center or doctor immediately
Symptoms to Watch: Headaches, dizziness, rash, breathing difficulty, stomach pain
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, foam; avoid water streams directly on burning product
Specific Hazards: Vapors may form explosive mixtures with air, burning releases toxic gases including nitrogen oxides and sulfur oxides
Protective Equipment: Full turnout gear, self-contained breathing apparatus
Advice for Firefighters: Approach fire from upwind, prevent runoff to drains or waterways, cool containers exposed to fire with water spray
Personal Precautions: Evacuate area, ventilate, wear chemical splash goggles, gloves, anti-static boots
Environmental Precautions: Prevent spills from reaching drains, surface water, soil; alert local authorities if significant spillage occurs
Cleanup Methods: Absorb with inert material (sand, earth, vermiculite), transfer to closed, labeled containers for disposal
Decontamination: Rinse the spill area with soap and water following pickup, use approved industrial cleaners
Precautions for Handling: Work in a ventilated area or under fume hood, avoid inhaling vapors, avoid contact with skin/eyes, keep away from flames, sparks, or static
Storage Conditions: Store in tightly closed, clearly labeled non-metallic containers in a cool, well-ventilated place, segregate from oxidizers and acids
Technical Controls: Use explosion-proof equipment, ensure ground/bonding of transfer lines and containers
Hygiene Measures: Wash hands after handling, no eating, drinking, or smoking in work area
Occupational Exposure Limits: No specific official limits; minimize exposure by following workplace controls
Engineering Controls: Good local exhaust ventilation, fume hoods where available, limit sources of ignition
Personal Protective Equipment (PPE): Safety goggles or face shield, chemical-resistant gloves (nitrile or neoprene), flame-resistant lab coat, splash-resistant shoes or boots
Respiratory Protection: If exposure risk exists, use NIOSH/MSHA-approved organic vapor respirator
Form: Liquid
Color: Pale yellow to brown
Odor: Strong, sulfurous, reminiscent of garlic or decaying vegetables
Melting Point: Data not available; generally liquid at room temperature
Boiling Point: ~205°C
Flash Point: 60°C (closed cup)
Solubility: Limited solubility in water, miscible with many organic solvents
Vapor Pressure: Moderate at room temperature; use caution without proper ventilation
pH: Not applicable
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Avoid strong acids, strong oxidizers, bases—reaction may liberate hazardous gases or cause violent exotherms
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Polymerization: No self-polymerization risk documented
Conditions to Avoid: Heat, flames, sparks, static discharge, incompatible chemical storage
Acute Effects: Harmful or fatal by ingestion, irritant by inhalation, skin and eye contact
Chronic Effects: Long-term, repeated exposures increase risk of sensitization, dermatitis, respiratory symptoms in susceptible people
Routes of Exposure: Inhalation, ingestion, skin, eyes
LD50 (oral/rat): Estimated in the range of 50-300 mg/kg (moderately toxic)
Symptoms: Throat soreness, headaches, abdominal pain, rash, coughing
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Other Data: Insufficient evidence for reproductive or developmental risks
Ecotoxicity: Harmful to aquatic life even at low concentrations, can accumulate in sediment and disrupt aquatic ecosystems
Persistence and Degradability: May not break down quickly in soil or water; potential for bioaccumulation
Mobility in Soil: Spilled product may migrate, enter groundwater streams
Other Concerns: Avoid uncontrolled release—contaminates water, harms wildlife
Waste Treatment: Dispose as hazardous chemical waste, do not pour down drain
Container Disposal: Rinse empty containers with solvent, triple rinse, puncture or crush, dispose in accordance with local/state/federal requirements
Disposal Methods: Use licensed chemical waste incinerators, contact certified waste handlers
Special Precautions: Segregate waste from acids, oxidizing agents, and reactives
UN Number: 3334
Proper Shipping Name: Aviation Regulated Liquid, N.O.S. (Pyrazinylethanethiol)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Label Requirements: Flammable liquid, toxic substance
Marine Pollutant: Yes, avoid shipment in bulk near marine environments
Special Provisions: Check for country-specific labeling and handling guidelines for road, sea, and air transport
OSHA Status: Regulated hazardous substance
TSCA Inventory: Listed
REACH Registration: Producers/importers must check latest status for tonnage thresholds
SARA Title III: Immediate and fire-related health hazards; reportable in case of major release
WHMIS Classification (Canada): B2 (Flammable Liquid), D1B (Toxic Materials), D2B (Skin/Eye Irritant)
Other International Regulations: Restricted for public sale in many countries; check with customs and health agencies before import/export
