Chemical Name: Pyrazine-2-Carboxylic Acid
Synonyms: 2-Pyrazinecarboxylic acid; 2-carboxypyrazine
Chemical Formula: C5H4N2O2
Molecular Weight: 124.10 g/mol
CAS Number: 98-97-5
Product Use: Laboratory chemical, intermediate for chemical synthesis
Manufacturer/Supplier: Name and emergency contact information, address, and phone number provided on accompanying documentation
Emergency Contact: CHEMTREC hotline or equivalent emergency response provider
Classification: Not classified as a hazardous substance according to GHS.
Signal Word: None
Pictogram: None
Hazard Statements: May cause irritation to eyes, skin, and respiratory tract. Dust formation may lead to discomfort if inhaled.
Precautionary Statements: Avoid breathing dust. Use in areas with proper ventilation. Avoid contact with skin and eyes. Wash hands before eating or drinking.
Other Hazards: No data indicating flammability, carcinogenicity, or other chronic health effects under current regulatory lists.
Chemical Name: Pyrazine-2-Carboxylic Acid
CAS Number: 98-97-5
Concentration: 100%, unless otherwise stated in source labeling or batch documentation
Impurities: Impurities, if present, are trace-level and not considered hazardous under normal use conditions
Inhalation: Move person to fresh air. If symptoms persist, seek medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting. Consult physician if symptoms occur.
Skin Contact: Remove contaminated clothing. Wash skin with soap and water for at least 15 minutes. Seek medical attention if irritation develops.
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes, occasionally lifting upper and lower eyelids. Get medical attention if irritation persists.
Specific Symptoms: Possible irritation, redness, coughing, or burning sensation depending on exposure route.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide for extinguishing flames.
Unsuitable Extinguishing Media: Do not use strong water streams that may spread product.
Fire Hazards: Product is not known to be flammable, but combustion may produce irritating fumes or toxic gases such as nitrogen oxides and carbon oxides.
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus.
Special Precautions: Move containers from fire area if safe; cool containers with water spray to prevent pressure build-up.
Personal Precautions: Put on appropriate protective clothing, avoid dust creation, ventilate area.
Environmental Precautions: Prevent entry into drains, sewers, and waterways. Avoid discharge to environment beyond controlled laboratory or facility.
Containment and Cleaning: Sweep or scoop up material into a waste container. Minimize dust generation. Wash spill site after material pick-up is complete.
Reporting Requirements: Report large spills or releases, especially if they reach a waterway or municipal system.
Handling: Handle in a chemical fume hood or well-ventilated area. Use personal protective equipment to avoid dust contact. Do not eat or drink during handling.
Storage Conditions: Store in a tightly closed container, in a cool, dry, well-ventilated location away from incompatible materials.
Incompatible Materials: Strong oxidizers or reducing agents. Keep away from sources of ignition.
Specific Use(s): For laboratory and industrial use by trained personnel.
Occupational Exposure Limits: No established exposure limits for this chemical under OSHA, ACGIH, or NIOSH.
Engineering Controls: Use local exhaust ventilation or laboratory fume hood.
Personal Protective Equipment:
Eye Protection: Safety goggles or face shield.
Skin Protection: Nitrile gloves and lab coat or apron.
Respiratory Protection: Dust mask or particulate respirator if airborne dust is generated.
General Hygiene: Wash hands thoroughly after handling. Remove contaminated clothing.
Appearance: White to off-white crystalline powder
Odor: Odorless or weak organic odor
Odor Threshold: Data not available
pH: Neutral to slightly acidic in solution
Melting Point: 210-213 °C (decomposition begins above this range)
Boiling Point: Not applicable (decomposes prior to boiling)
Flash Point: Not applicable
Flammability: Not flammable under normal conditions
Solubility: Slightly soluble in water, soluble in organic solvents like ethanol and DMSO
Vapor Pressure: Not relevant for a solid
Density: Approximately 1.5 g/cm3
Partition Coefficient (log Kow): 0.36 (estimated)
Decomposition Temperature: Above 210 °C
Evaporation Rate: Not applicable
Chemical Stability: Stable under recommended storage conditions in original packaging.
Reactivity: Not reactive under normal laboratory conditions.
Conditions to Avoid: Excessive heat, sources of ignition, and contact with incompatibles.
Incompatible Materials: Strong oxidizing agents, reducing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides on combustion or decomposition.
Polymerization: Will not occur.
Acute Toxicity: Data limited. Oral LD50 (rat) >2000 mg/kg based on readings from similar pyrazine derivatives.
Skin Corrosion/Irritation: May cause mild skin irritation on direct contact.
Eye Damage/Irritation: May cause eye irritation.
Respiratory Sensitization: Prolonged inhalation of dust may cause mild respiratory tract discomfort.
Carcinogenicity: Not listed as carcinogenic by NTP, IARC, ACGIH, or OSHA.
Mutagenicity: No information found linking to genetic defects.
Reproductive Toxicity: No information available.
STOT-Repeated Exposure: No data suggesting target organ toxicity.
Other Data: Avoid unnecessary contact; effects from repeated or prolonged exposure are not fully documented due to lack of detailed toxicological studies.
Ecotoxicity: No specific data for aquatic or terrestrial toxicity. Precaution suggested to avoid large releases due to possible risks to aquatic organisms.
Persistence and Degradability: Expected to degrade slowly under natural conditions by hydrolysis and microorganisms.
Bioaccumulative Potential: Low potential, based on predicted log Kow and water solubility.
Mobility in Soil: Moderate mobility based on solubility data.
Other Adverse Effects: No significant ozone depletion, photochemical smog, or greenhouse gas contributions.
Waste Treatment Methods: Dispose of in compliance with local, regional, and national regulations. Use licensed chemical disposal contractor.
Contaminated Packaging: Triple rinse containers, render packaging unusable before offering for recycling or disposal.
Special Precautions: Do not allow substance to enter public waterways; label and segregate chemical waste appropriately.
Recommended Disposal: Incineration via permitted facility or secure landfill if permitted by local laws.
UN Number: Not classified for transport as dangerous goods.
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Marine Pollutant: No
Special Precautions for User: Avoid release to environment during transport.
Transport in Bulk: Not applicable.
OSHA Hazard Communication: Substance not listed as hazardous, but follow general laboratory safety guidelines.
TSCA Inventory: Listed
SARA Title III Section 313: Not listed
California Proposition 65: Not listed
REACH Registration: Exempt or not classified for European market; consult specific dossier.
Canadian DSL/NDSL: Listed
Other National Inventories: Consult local regulatory authorities as product may not be subject to restrictions in all regions.
