Product Name: Piperazine-1-dithiocarboxylic acid
Chemical Formula: C3H8N2S2
Synonyms: 1,4-Dithiocarbamoylpiperazine
CAS Number: 5351-27-9
Recommended Use: Chemical synthesis, intermediate
Supplier Details: Supplier contact information, company address, emergency phone number
Emergency Telephone: Local or national poison control, CHEMTREC hotline
Classification: Acute toxicity (oral, dermal), skin corrosion/irritation, eye damage/irritation
GHS Label Elements: Pictogram for acute toxicity, exclamation mark for irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed or in contact with skin, causes skin and serious eye irritation
Precautionary Statements: Avoid contact with eyes, skin, and clothing; wash hands after handling; wear protective gear
Other Hazards: Dust or vapors may cause respiratory tract irritation, precaution needed around open containers
Chemical Name: Piperazine-1-dithiocarboxylic acid
Concentration: 98–100%
Impurities: Trace related dithiocarbamic species (<1%), water (<1%)
CAS Number: 5351-27-9
EINECS Number: 226-327-6
Inhalation: Remove person to fresh air; seek medical advice if symptoms develop
Skin Contact: Remove contaminated clothing, immediately wash with soap and water; medical attention for persistent irritation
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes; seek medical care
Ingestion: Rinse mouth, never induce vomiting unless directed by medical personnel, contact poison center or doctor
Symptoms: Coughing, skin redness, nausea, burning sensation in eyes or respiratory tract
Suitable Extinguishing Media: Dry chemical, CO2, alcohol-resistant foam, or water spray
Hazardous Combustion Products: Sulfur oxides, nitrogen oxides, carbon monoxide, carbon dioxide
Firefighting Instructions: Use self-contained breathing apparatus and full protective suit; keep containers cool with water spray; move personnel to safe distance
Special Hazards: Explosion risk from dust and thermal decomposition; toxic fumes released under fire conditions; closed containers may rupture
Personal Precautions: Wear gloves, chemical goggles, protective clothing; ventilate area; avoid inhaling dust or vapors
Environmental Precautions: Prevent from entering soil, drains, surface water or groundwater; notify local authorities if contamination occurs
Clean-Up Procedures: Sweep up and place in suitable, labeled container for disposal; avoid creating dust; decontaminate area with detergent and water
Spill Control: Stop leak if safe, contain spill using absorbent material; ventilate area during cleanup
Safe Handling: Use only with adequate ventilation; wear suitable protective equipment; avoid generating dust; do not eat, drink, or smoke during use
Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated place away from incompatible materials like strong oxidizers and acids
Packaging Materials: Use containers resistant to acids and moisture; label containers properly
Incompatibilities: Avoid direct sunlight, moisture, and sources of ignition; separate from oxidizing materials
Exposure Limits: No specific occupational exposure limits established; minimize exposure by process enclosure and local exhaust
Engineering Controls: Work in chemical fume hood or with local exhaust ventilation
Respiratory Protection: Use NIOSH-approved dust respirator if airborne concentration may exceed limits
Hand Protection: Impervious gloves such as nitrile or neoprene; check for leaks regularly
Eye Protection: Safety goggles or face shield
Skin Protection: Long-sleeve protective clothing, chemical apron
Work Hygiene: Wash thoroughly after handling, before breaks and eating; keep work clothes separate
Appearance: White to pale yellow crystalline powder
Odor: Slight sulfur-like odor
Odor Threshold: Not available
Melting Point / Freezing Point: 160–163 °C (320–325 °F)
Boiling Point / Range: Decomposes before boiling
Flammability: Not readily flammable, but combustible
Vapor Pressure: Negligible at ambient temperature
Solubility: Slightly soluble in water; soluble in alcohol and acetone
Partition Coefficient: Not available
pH: Not determined
Viscosity: Not available
Other Properties: Dust may form explosive mixture with air under certain conditions
Chemical Stability: Stable under recommended conditions, unstable when exposed to moisture and heat
Reactivity: Reacts with strong acids, oxidizers, and reducing agents
Hazardous Reactions: Decomposes with evolution of toxic gases (hydrogen sulfide, nitrogen oxides) if heated or mixed with incompatible materials
Conditions to Avoid: Heat, flame, static discharge, incompatible chemicals
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, sulfur oxides, hydrogen sulfide gas
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: LD50 (oral, rat): approx. 500 mg/kg
Skin Corrosion/Irritation: Causes moderate to severe skin irritation
Serious Eye Damage/Irritation: Causes eye burns, potential for permanent damage
Respiratory or Skin Sensitization: May cause allergic reaction after repeated contact
Chronic Effects: Prolonged exposure could affect liver and kidney function
Mutagenicity: No data available for mutagenic effects; handle with care
Other Effects: No reproductive toxicity data available; repeated exposure may aggravate pre-existing conditions
Ecotoxicity: Harmful to aquatic life; releases toxic sulfur compounds which may affect water quality
Persistence and Degradability: Not readily biodegradable; breakdown may generate hazardous residues
Bioaccumulation: No data on bioaccumulation; avoid uncontrolled release into environment
Mobility in Soil: Moderate mobility expected due to low water solubility
Other Adverse Effects: Do not allow material to contaminate ground water or sewage systems
Disposal Methods: Dispose in accordance with local, regional, and national regulations; incineration under controlled conditions is recommended
Contaminated Packaging: Rinse containers thoroughly before disposal, dispose as hazardous waste
Other Precautions: Do not reuse empty containers; avoid release to environment during disposal
UN Number: Not assigned
UN Proper Shipping Name: Non-regulated under standard transport regulations
Transport Hazard Class: Not classified as dangerous for transport
Packing Group: Not applicable
Environmental Hazards: Avoid spillage; not a marine pollutant by regulation, but hazardous to aquatic environments
Special Transport Precautions: Keep containers upright and tightly closed; protect from physical damage
SARA Title III (USA): Not listed under Sections 302, 304, or 313
OSHA (USA): Classified for occupational exposure due to acute toxicity and irritation hazards
TSCA (USA): Listed or subject to TSCA regulations
REACH (EU): Not registered; only available in quantities for research and development or under exemption
WHMIS (Canada): Classified as hazardous, consult local classification guide
Other Regulations: Product must be handled according to established chemical hygiene and hazard communication standards; update MSDS periodically
