Product Name: Pidolic Acid
Chemical Name: Pyrrolidone Carboxylic Acid
CAS Number: 98-79-3
Synonyms: PCA, L-Pyroglutamic Acid
Recommended Use: Laboratory reagent, pharmaceutical intermediate, cosmetic ingredient
Manufacturer: [Company Name], [Company Address]
Emergency Contact: [Emergency Number Available 24/7]
Email Contact: [Manufacturer Email]
GHS Classification: Not classified as hazardous according to GHS criteria.
Signal Word: None
Hazard Statements: May cause mild skin or eye irritation in rare cases.
Precautionary Statements: Avoid contact with skin, eyes, and clothing. Do not breathe dust.
Potential Health Effects: Low toxicity expected. Prolonged exposure in sensitive persons can lead to redness of skin or watery eyes. Inhalation of large amounts may cause mild respiratory irritation.
Environmental Hazards: Low, but large-scale spills could impact aquatic environments.
Other Hazards: Dust may create slipping hazard on smooth surfaces.
Chemical Name: Pidolic Acid
CAS Number: 98-79-3
Concentration: 99% minimum by weight
Impurities: Trace inorganic salts (<0.5%), water (<0.5%)
Inhalation: Remove to fresh air, keep at rest in a comfortable position, seek medical attention if symptoms persist.
Skin Contact: Immediately wash with soap and water, remove contaminated clothing, seek medical attention if irritation continues.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, get medical attention if irritation occurs.
Ingestion: Rinse mouth, never induce vomiting unless directed by medical professional, seek medical assistance if large amounts swallowed or symptoms occur.
Most Important Symptoms: Slight eye or skin irritation is possible.
Indication of Immediate Medical Attention: Unconsciousness, severe or persistent symptoms require immediate care.
Suitable Extinguishing Media: Water spray, dry chemical, foam, or carbon dioxide.
Unsuitable Extinguishing Media: Strong water jets may spread powder.
Specific Hazards: Fine dust in air can lead to risk of explosion in confined spaces.
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides.
Advice for Firefighters: Wear self-contained breathing apparatus and protective clothing, avoid inhaling fumes, use water spray to cool containers at risk.
Special Procedures: Remove containers from fire area if this can be done safely.
Personal Precautions: Use personal protection, avoid creating or breathing dust, ensure ventilated area.
Environmental Precautions: Prevent entry into waterways, drains, soil.
Containment Methods: Sweep up with minimal dust generation, transfer to suitable waste container.
Cleanup Methods: Use damp cloth or vacuum with HEPA filter for residues, wash area with soap and water.
Disposal: Dispose as described below in local or national regulations.
Safe Handling: Avoid contact with eyes, skin, and clothing, handle in well-ventilated area, avoid dust formation, wash hands thoroughly after use.
Hygiene Measures: No eating, drinking, or smoking when using the material, wash hands before breaks and after handling.
Safe Storage Conditions: Store tightly closed in original container, in cool, dry, well-ventilated place.
Incompatible Materials: Strong oxidizing agents, strong bases.
Storage Area: Keep away from heat sources, open flame, and out of direct sunlight, recommended temperature 15-25°C.
Exposure Limits: No occupational exposure limits established for this substance.
Engineering Controls: Local exhaust ventilation to control dust.
Personal Protective Equipment:
- Skin: Wear chemical-resistant gloves such as nitrile.
- Eyes: Use safety glasses with side shields or chemical goggles.
- Respiratory Protection: Use dust mask under dusty conditions.
- Other: Laboratory coat or protective clothing, use foot protection in spill areas.
Control of Environmental Exposure: Use containment to prevent release to environment, comply with regulatory requirements.
Appearance: White crystalline powder
Odor: Odorless or faintly acetic
Odor Threshold: Not determined
pH (1% Solution): 3.0–4.0
Melting Point: 151–156°C
Boiling Point: Decomposes before boiling
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable under normal conditions
Explosive Properties: Dust may cause risk of explosion in air
Relative Density: 1.4–1.5 g/cm³
Solubility: Soluble in water, slightly soluble in alcohol
Partition Coefficient (log Kow): -2.26
Vapor Pressure: Not relevant at room temperature
Auto-ignition Temperature: Data not available
Decomposition Temperature: Above 190°C
Molecular Formula: C5H7NO3
Molecular Weight: 129.11 g/mol
Chemical Stability: Stable under normal temperatures and pressures.
Reactivity: Not spontaneously reactive.
Possible Hazardous Reactions: Combines with strong oxidizers to form heat or hazardous products.
Conditions to Avoid: Excessive heat, moisture, and incompatible substances.
Incompatible Materials: Strong alkalis, strong oxidants.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Acute Toxicity:
- Oral LD50 (rat): >2000 mg/kg (low acute toxicity reported)
- Dermal LD50 (rat): Not determined, expected low toxicity
- Inhalation LC50: Not determined, dust can irritate respiratory tract
Skin Corrosion/Irritation: May cause mild irritation in sensitive individuals
Eye Damage/Irritation: Mild, transient eye irritation possible
Respiratory Sensitization: Data not available
Germ Cell Mutagenicity: No evidence of mutagenicity
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No adverse reproductive effects reported
STOT Single Exposure: Not classified
STOT Repeated Exposure: Not classified
Aspiration Hazard: Not an aspiration hazard
Ecotoxicity: Expected to have low toxicity to aquatic life
Persistence and Degradability: Biodegradable in soil and water, does not persist
Bioaccumulation: Not expected to bioaccumulate due to low log Kow
Mobility in Soil: High mobility due to solubility in water
Other Adverse Effects: None known
Waste Treatment Methods: Dispose of waste through licensed waste disposal contractor, comply with local, regional, and national regulations
Product Disposal: Avoid release to environment, incinerate or landfill as permitted by government regulations
Contaminated Packaging: Reuse or recycle containers when possible, otherwise send for disposal as hazardous waste after proper cleaning
Other Disposal Recommendations: Do not dispose with general household waste, consult environmental authorities for guidance
UN Number: Not classified as hazardous for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class(es): None
Packing Group: Not applicable
Environmental Hazards: Not considered a marine pollutant
Transport in Bulk: No special requirements
Special Precautions for User: Protect from water and sealed tightly during transport to prevent clumping or contamination
TSCA (USA): Listed
DSL (Canada): Listed
REACH (EU): Listed or exempted
OSHA Hazards: Not considered hazardous
SARA Title III (USA): Not a Section 313 chemical
California Prop 65: Substance not listed
Other National or International Regulations: Complies with standards for laboratory, cosmetic, and pharmaceutical use as required by relevant authorities
