Material Safety Data Sheet for Phthalylsulfathiazole

Identification

Product Name: Phthalylsulfathiazole
Chemical Name: N-(phthalyl)-sulfathiazole
CAS Number: 85-73-4
Recommended Use: Antibacterial agent in medical or veterinary applications
Manufacturer: Listed manufacturer or distributor details as per local supply chain
Emergency Contact Number: Local poison control center or emergency responder

Hazard Identification

Classification: Irritant; may cause eye, skin, and respiratory irritation
Signal Word: Warning
Hazard Statements: May irritate eyes and skin; possible allergy on prolonged contact; may cause digestive tract discomfort if swallowed
Precautionary Statements: Avoid inhalation, ingestion, and prolonged contact with skin; wear appropriate protective gear
Other Hazards: Dust formation may create respiratory risk in poorly ventilated spaces

Composition / Information on Ingredients

Chemical Identity: Phthalylsulfathiazole
Chemical Formula: C17H9N3O5S2
Purity: Greater than 98% as active compound
Impurities: Minor byproducts from synthesis potentially below 1%; unreacted intermediates possible in trace amounts
Common Name: Phthalylsulfathiazole

First Aid Measures

Inhalation: Move affected person to fresh air; seek medical attention if symptoms develop
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing; medical attention if irritation persists
Eye Contact: Rinse eyes with clean water for several minutes; remove contact lenses; visit healthcare professional if irritation does not resolve
Ingestion: Rinse mouth with water; never give anything by mouth to an unconscious person; seek immediate medical assistance if large amounts swallowed

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, foam, or dry chemical
Specific Hazards: May emit toxic smoke or gases such as nitrogen oxides and sulfur oxides on combustion
Protective Equipment: Firefighters wear self-contained breathing apparatus and protective clothing
Special Precautions: Avoid inhaling fumes; control runoff water to prevent environmental contamination

Accidental Release Measures

Personal Precautions: Use personal protective equipment including gloves, goggles, and dust mask
Environmental Precautions: Prevent material from entering drains, surface water, or soil
Cleanup Methods: Sweep up and collect in an appropriate labeled container for disposal; use wet methods to minimize dust production
Other Precautions: Ventilate the area and prevent further leakage or spillage if safe to do so

Handling and Storage

Handling: Use in well-ventilated spaces; reduce dust generation; do not get in eyes, on skin, or on clothing; wash thoroughly after handling
Storage: Store in tightly closed containers away from moisture and incompatible materials; keep in a cool, dry area with limited access
Incompatibilities: Strong oxidizing agents
Storage Class: General chemical storage with restricted access to authorized personnel

Exposure Controls and Personal Protection

Engineering Controls: Local exhaust ventilation recommended in processing areas
Respiratory Protection: Use approved dust mask or respirator if dust levels risk occupational exposure
Skin Protection: Chemical-resistant gloves; protective clothing recommended
Eye Protection: Safety goggles or face shield
Hygiene Measures: Wash hands before breaks and after handling; do not eat or drink while using material

Physical and Chemical Properties

Appearance: White to light yellow crystalline powder
Odor: Odorless
Molecular Weight: 399.39 g/mol
Melting Point: Around 315-317°C
Solubility: Practically insoluble in water; slightly soluble in alcohol
pH: Not available due to insolubility in water
Vapor Pressure: Data not available; low volatility expected
Boiling Point: Decomposes before boiling
Partition Coefficient (log Kow): Not readily available; likely low due to structure

Stability and Reactivity

Chemical Stability: Stable under normal conditions of use and storage
Conditions to Avoid: Excessive heat, direct sunlight, and moisture
Incompatible Materials: Oxidizing agents, acids, strong bases
Decomposition Products: Thermal decomposition can produce hazardous fumes like sulfur dioxide, nitrogen oxides, and carbon monoxide
Hazardous Reactions: No hazardous polymerization expected

Toxicological Information

Acute Toxicity: Oral LD50 in rodents above common pharmaceutical dosages; low acute toxicity for single exposure
Skin Corrosion/Irritation: May irritate sensitive skin on prolonged or repeated exposure
Eye Damage/Irritation: Risk of mild irritation
Respiratory Irritation: Dust may provoke mild to moderate irritation of airways
Sensitization: Some cases of allergenic responses after skin contact have occurred
Chronic Effects: Long-term exposure possible risk of hypersensitivity; animal studies do not show significant carcinogenic or mutagenic potential

Ecological Information

Ecotoxicity: Limited data available; low acute risk to aquatic life expected at normal environmental concentrations
Persistence and Degradability: Likely to degrade slowly in soil or water; low volatility into air
Bioaccumulation Potential: Low due to poor lipid solubility
Mobility in Soil: Low mobility; binds to soil particles
Other Adverse Effects: Do not release in large quantities into waterways to prevent potential harm to aquatic life

Disposal Considerations

Disposal Methods: Incinerate under controlled conditions or dispose at an approved chemical landfill; observe all local, state, and national regulations
Contaminated Packaging: Dispose of as hazardous waste; avoid reuse of containers
Precautions: Do not allow product to reach sewage system or water bodies; consult licensed waste disposal contractor for guidance

Transport Information

UN Number: Not classified as hazardous for transport
Transport Hazard Class: Not regulated as dangerous goods under standard shipping regulations
Packing Group: Not applicable
Environmental Hazards: Not considered marine pollutant in normal quantities
Special Precautions: Ship in tightly closed containers; avoid exposure to wet conditions or rough handling to prevent spills

Regulatory Information

Safety, Health, and Environmental Regulations: Product subject to national and international chemical safety guidelines
OSHA/NIOSH: Not listed as workplace hazardous material, but observe general safety principles
SARA Title III: Not listed as an extremely hazardous substance under Section 302
TSCA Status: Included in US Toxic Substances Control Act inventory
Other Regulations: Handle and dispose of according to local, regional, and national laws; maintain records as required by regulatory authorities