Product Name: Phthaleinsulfathiazole
Chemical Formula: C17H13N3O5S2
CAS Number: 65-72-3
Synonyms: Sulphathalein, Sulfathalazine
Manufacturer/Supplier: [Insert organization/contact details]
Intended Use: Pharmaceutical compound primarily for gastrointestinal infection management.
Emergency Contact: [Insert local emergency phone number and supplier contact]
Hazard Classification: Eye irritant, possible respiratory allergen, low acute oral toxicity
Label Elements: Pictograms for health hazard and exclamation mark
Signal Word: Warning
Hazard Statements: Irritates eyes and may trigger respiratory symptoms in sensitive individuals.
Precautionary Statements: Do not breathe dust, wash hands thoroughly; avoid contact with skin and eyes.
Physical Hazards: Fine, pale powder can form dust clouds; may cause mechanical irritation.
Environmental Hazard: At high concentrations, runoff might affect aquatic organisms.
Chemical Identity: Phthaleinsulfathiazole
Concentration: Approximately 100% pure
Impurities: Typically pharmaceutical grade, insignificant impurity levels
Other Additives: None in raw form
CAS Number: 65-72-3
Molecular Weight: 419.44 g/mol
Inhalation: Bring affected person to fresh air; seek medical advice if coughing or shortness of breath develops.
Skin Contact: Rinse area with soap and water; remove contaminated clothing.
Eye Contact: Flush with plenty of clean water for at least 15 minutes, keeping eyelids open.
Ingestion: Rinse mouth, drink water; consult medical attention especially if nausea or abdominal pain develops.
Most Important Symptoms: Eye irritation, transient coughing, mild nausea.
Notes for Doctors: Symptomatic treatment; allergies possible in sensitized individuals.
Suitable Extinguishing Media: Use dry powder, foam, or carbon dioxide.
Unsuitable Media: Direct water jets (may disperse powder).
Special Hazards: Decomposition may release sulfur oxides, carbon monoxide, and nitrous fumes.
Precautions for Firefighters: Use self-contained breathing apparatus and protective clothing in confined spaces.
Additional Info: Keep dust clouds away from open flames; can become slippery when wet.
Personal Precautions: Use gloves, dust mask, and eye protection; do not touch eyes or face.
Methods for Cleanup: Gather spilled powder using wet cloth or HEPA vacuum; avoid generating dust.
Environmental Precautions: Prevent large quantities from entering drains, water bodies.
Disposal of Waste: Place in marked, sealed container for chemical disposal.
Emergency Procedures: Ventilate area; keep unnecessary personnel away.
Handling: Use with local exhaust if dust forms; minimize contact and wash hands after use.
Storage Conditions: Store in cool, dry, well-ventilated place.
Packaging: Keep container tightly closed, labeled with hazard warnings.
Incompatible Materials: Strong acids or oxidizers.
Other Considerations: Limit storage amount in open areas to reduce dust risk.
Engineering Controls: Use local exhaust ventilation where dust develops.
Personal Protective Equipment: Chemical-resistant gloves, safety goggles, dust mask; avoid cotton gloves that soak through.
Hygiene Measures: No eating, drinking, or smoking in working area; wash hands thoroughly after handling.
Exposure Limits: No established occupational limits; treat as nuisance dust (set at 10 mg/m³ OSHA PEL for particulates not otherwise regulated).
Environmental Controls: Prevent product from entering waterways.
Appearance: Pale yellow to off-white powder
Odor: Odorless or slight medicinal odor
pH: Neutral in aqueous suspension
Melting Point: 288–290°C
Solubility: Limited solubility in water; soluble in dilute alkali
Boiling Point: Decomposes before boiling
Density: 1.58 g/cm³
Vapor Pressure: Negligible at room temperature
Other Properties: Stable under standard conditions; may yellow with exposure to light.
Chemical Stability: Stable under normal storage and environmental conditions.
Reactivity: Unreactive with most chemicals under standard use; reacts with strong acids or bases.
Decomposition: Heat or strong oxidizers can break down compound, releasing toxic fumes.
Hazardous Reactions: Avoid mixing with strong oxidizing substances.
Conditions to Avoid: Moist air, excessive heat, open flames.
Acute Toxicity: Oral LD50 (rat) > 15,000 mg/kg; low hazard in single exposures.
Chronic Exposure: Sensitive individuals might develop allergic reactions or gastrointestinal discomfort.
Routes of Exposure: Inhalation, skin, eyes, ingestion.
Symptoms: Redness of eyes, mild throat or skin irritation, upset stomach.
Carcinogenicity: Not classified as carcinogenic.
Mutagenicity/Reproductive Effects: Not reported in available studies.
Sensitization: Prolonged contact may cause skin sensitization in rare cases.
Aquatic Toxicity: Limited data, but not considered highly toxic.
Persistence and Degradability: Slowly degrades in the environment; not readily biodegradable.
Bioaccumulation: No significant potential for bioaccumulation expected.
Mobility: Low solubility limits mobility through soil and water.
Environmental Impact: High concentrations could disrupt local microbial processes in water bodies.
Waste Disposal Methods: Collect and place waste material in sealed chemical containers.
Disposal Facilities: Use licensed contractor for chemical waste treatment.
Do Not: Dump into sewers or water sources.
Packaging Disposal: Rinse containers before recycling if allowed; otherwise, handle as hazardous waste.
Reference Regulations: Dispose in accordance with local, regional, national laws on pharmaceutical chemicals.
UN Number: Not classified as hazardous for transport.
Shipping Name: Phthaleinsulfathiazole, bulk or packaged
Transport Hazards: Avoid heavy impact or spillage.
Packing Group: Not assigned.
Special Precautions: Label clearly; keep secure to avoid unauthorized access.
Mode of Transport: No restrictions by road, rail, air, or sea when properly packed.
Label Requirements: Complies with OSHA, EU CLP labeling for chemical substances.
Safety Assessments: Hazard communication sheets required where handled.
Inventory Listings: Registered under most national chemical inventory frameworks.
Workplace Controls: Covered by regional chemical safety laws.
SARA Title III: Not listed as a reportable substance.
Other Regulations: Review national guidelines for pharmaceutical products.
