Product Name: Perphenazine
Chemical Name: 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
Common Names: Trilafon
Recommended Use: Antipsychotic medication
Manufacturer: Please refer to packaging or supplier details
Contact Details: Supplier-specific, generally includes emergency phone numbers
Emergency Contact: Local poison control, medical personnel, or company hotline
Physical State: Solid (commonly supplied as a tablet or powder)
Major Health Hazards: May cause central nervous system depression or stimulation, respiratory depression, drowsiness, dizziness, dry mouth, nausea, blurred vision, and muscle spasms
Potential Environmental Effects: Hazardous to aquatic life, may persist in the environment
Warning Labels: Toxic if swallowed or inhaled, possible skin and eye irritant, avoid ingestion or prolonged exposure
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Main Ingredient: Perphenazine (CAS No. 58-39-9), typically 100% for pure substance or as indicated on formulation
Impurities: Manufacturing residuals and breakdown products may present, as detailed by producer
Other Ingredients: When in tablet form, non-active substances like lactose, microcrystalline cellulose, and coloring agents often included
Inhalation: Move person to fresh air at once, offer oxygen if breathing becomes difficult, seek medical help promptly
Skin Contact: Wash affected area thoroughly with water and soap, remove contaminated clothing and throw away if needed, get medical attention for irritation
Eye Contact: Rinse with water gently for several minutes, remove contacts carefully, consult healthcare professional if irritation continues
Ingestion: Rinse mouth, do not induce vomiting unless suggested by medical workers, call for medical help immediately—monitor for low consciousness or trouble breathing
Suitable Extinguishing Media: Water spray, foam, dry chemical, or CO2
Hazards from Fire: May emit toxic fumes like carbon monoxide, nitrogen oxides, sulfur oxides, hydrogen chloride
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear, move containers away from fire if safe
Precautions: Avoid smoke or fumes, cool containers with water spray to prevent explosion or bursting from heat
Personal Precautions: Use personal protective equipment such as gloves, goggles, and respirator to prevent contact and inhalation
Environmental Precautions: Prevent product from entering drains, waterways, and soil, contain spill with sand, vermiculite, or earth
Clean-Up Methods: Scoop or sweep up without creating dust, place in labeled container for proper disposal, ventilate concerned area
Handling: Avoid breathing dust or powders, do not eat, drink, or smoke during use, practice good personal hygiene like frequent hand washing
Storage: Keep container tightly closed in a cool, dry, well-ventilated location, protect from light and excessive moisture, store away from incompatible materials
Exposure Limits: No specific occupational exposure limits set for perphenazine; general dust limits may apply
Engineering Controls: Use local exhaust ventilation or process enclosures to minimize airborne dust
Personal Protective Equipment: Gloves resistant to chemicals, safety eyewear with side shields or goggles, lab coats or overalls, respirators if dust concentration gets high
Hygiene Measures: Wash hands thoroughly after handling, avoid hand-to-mouth contact, take care with contaminated clothing
Appearance: White to off-white powder or crystalline solid, sometimes tablets
Odor: Nearly odorless
Molecular Formula: C21H26ClN3OS
Molecular Weight: 403.97 g/mol
Melting Point: 166-168°C
Solubility: Low water solubility; soluble in some organic solvents
pH: Data specific to solution form
Other Properties: Stable under ordinary use; avoid high heat or flames
Chemical Stability: Remains stable at room temperature and under recommended use conditions
Dangerous Reactions: Avoid strong oxidizers, strong acids or bases may break down product
Decomposition: May produce hazardous gases such as hydrogen chloride, nitrogen oxides, sulfur oxides under combustion or thermal decomposition
Polymerization: Not known to occur
Routes of Entry: Inhalation, ingestion, dermal, ocular
Short-Term Effects: Can cause nausea, sedation, confusion, dystonic reactions, blurred vision, tremor
Long-Term Effects: Possible tardive dyskinesia, persistent anticholinergic effects, rare risk of neuroleptic malignant syndrome
Chronic Exposure: Potential liver and blood effects, especially in sensitive populations
Sensitization: No conclusive evidence of sensitization
Carcinogenicity: Not classified as carcinogenic by ACGIH, NTP, IARC, or OSHA
Ecotoxicity: May be toxic to aquatic organisms, limited biodegradation, persistence possible
Mobility: Low volatility, may partition to soils or sediments
Bioaccumulation: Not enough data; structurally, risk can't be ruled out
Other Concerns: Keep out of natural waterways, unnecessary disposal poses ecological risk
Disposal Methods: Collect in sealed containers, send to permitted chemical waste disposal facility
Sewage Disposal: Do not release into sewers or water supplies
Container Handling: Clean containers thoroughly, follow regulations for hazardous waste
Local Regulations: Follow regional waste disposal rules; incineration often preferred for pharmaceuticals
Shipping Name: Perphenazine, pharmaceutical substances
Transport Hazard Class: Not classified as a hazardous material for land, air, or sea under most regulations; confirm with carrier
UN Number: None assigned
Packing Group: Not applicable
Special Precautions: Keep away from incompatible substances, store upright, follow package instructions
Regulations: Prescription medication—subject to national drug laws
Safety Laws: OSHA, Controlled Substances Act (by use), U.S. EPA regulations for chemical disposal
Labeling Requirements: Must display hazard and precautionary statements
Other Standards: Workplace safety standards set by national and local government, must comply with record-keeping and reporting obligations for hazardous drugs
