Product Name: Perhydroazepine
Chemical Name: Azepane
Synonyms: Hexamethyleneimine, Hexahydroazepine
CAS Number: 111-49-9
Molecular Formula: C6H13N
Recommended Use: Laboratory research, industrial chemical intermediate
Manufacturer: Information on manufacturer or supplier, emergency contact phone, and address required for workplace compliance
Distributor Contact: Emergency contact number accessible 24 hours
GHS Classification: Flammable liquid (Category 3), Acute toxicity (Oral, Category 4), Skin corrosion/irritation (Category 2), Eye irritation (Category 2A), Specific target organ toxicity - single exposure (Category 3)
Label Elements: Signal word: Warning; Hazard statements: Flammable liquid and vapor, Harmful if swallowed, Causes skin irritation, Causes serious eye irritation, May cause respiratory irritation
Precautionary Statements: Keep away from ignition sources, Keep container tightly closed, Avoid breathing vapor/mist, Wash thoroughly after handling, Wear protective gloves/eye protection/face protection
Hazards Not Otherwise Classified: May cause central nervous system effects, Prolonged or repeated contact may cause dermatitis or eye damage
Environmental Hazards: Toxic to aquatic life with long lasting effects
Chemical Component: Perhydroazepine
Concentration: 98% or higher
CAS Number: 111-49-9
Impurities and Stabilizers: None identified; product is a pure substance
EC Number: 203-876-4
Inhalation: Remove person to fresh air, keep comfortable for breathing, seek medical attention if symptoms persist or worsen, monitor for respiratory distress
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, remove contact lenses, continue rinsing, get medical attention
Skin Contact: Remove contaminated clothing and wash skin thoroughly with soap and water, seek medical attention if irritation persists
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, seek medical attention immediately
Most Important Symptoms: Respiratory irritation, nausea, dizziness, headache, skin and eye redness and pain
Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide, or alcohol-resistant foam
Unsuitable Extinguishing Media: Water jet
Special Hazards: Flammable vapors, combustion can produce nitrogen oxides, carbon monoxide, toxic fumes
Protective Equipment: Wear self-contained breathing apparatus and full protective clothing to prevent contact with skin and eyes
Specific Fire-Fighting Methods: Keep containers cool with water spray, use water spray or fog to minimize vapors, avoid inhaling combustion products
Personal Precautions: Evacuate area, ensure adequate ventilation, wear appropriate personal protective equipment including gloves, goggles, and respiratory protection
Environmental Precautions: Prevent further leakage or spillage, do not allow product to reach drains, surface water, or soil
Methods for Clean-up: Contain and collect spillage with inert absorbent material (sand, earth, vermiculite), place in suitable chemical waste container, ventilate area
Decontamination: Wash spill area with soap and water after material pick-up, dispose of in accordance with local regulations
Safe Handling: Use only in well-ventilated areas, avoid breathing vapors, avoid contact with skin, eyes or clothing, do not eat, drink or smoke while handling
Storage Conditions: Store in tightly closed original container, in a dry, cool, well-ventilated place, keep away from sources of ignition, heat, incompatible materials such as oxidizers
Special Precautions: Ground and bond containers when transferring, use spark-proof tools and explosion-proof equipment, label containers clearly
Exposure Limits: No established occupational exposure limits, follow good hygiene practices
Engineering Controls: Use local exhaust or general dilution ventilation to control airborne levels below recommended thresholds
Personal Protective Equipment: Chemical safety goggles, nitrile or neoprene gloves, flame-resistant lab coat, chemical-resistant apron if splashing is possible, suitable respiratory protection if exposure limits may be exceeded
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling chemicals, remove contaminated clothing and clean before reuse
Appearance: Colorless liquid
Odor: Ammonia-like, fishy
Odor Threshold: Not established
pH: Alkaline solution
Melting Point/Freezing Point: About -5°C
Boiling Point/Range: 156 – 158°C
Flash Point: 57°C (closed cup)
Evaporation Rate: Not available
Flammability: Flammable liquid
Upper/Lower Flammability Limits: Lower: 1.1% v/v, Upper: 7.2% v/v
Vapor Pressure: 3 mm Hg at 20°C
Vapor Density: 3.4 (air = 1)
Relative Density: 0.861 g/cm³
Solubility: Miscible with water
Partition Coefficient (log Kow): 0.46
Auto-ignition Temperature: 290°C
Decomposition Temperature: Not determined
Viscosity: 1.3 mPa·s at 20°C
Chemical Stability: Stable under normal handling and storage conditions
Reactivity: Can react with strong oxidizing agents and acids, exothermic reactions possible
Hazardous Reactions: Does not polymerize, but may form hazardous decomposition products
Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, irritating gases
Conditions to Avoid: Excessive heat, open flames, static discharge, direct sunlight
Incompatible Materials: Strong acids, strong oxidizing agents
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): ~670 mg/kg; Inhalation LC50: not established; Dermal LD50: not available
Symptoms: Eye and skin irritation, respiratory irritation, dizziness, headache, nausea, CNS depression at high exposures
Chronic Effects: Possible dermatitis from prolonged contact, repeated exposure may damage mucous membranes
Sensitization: No known sensitizing effects
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Not reported
Reproductive Toxicity: Not reported
Toxicity to Aquatic Life: Fish LC50 (96h): ~80 mg/L (Danio rerio); Daphnia EC50 (48h): ~53 mg/L
Persistence and Degradability: Biodegradable in water and soil
Bioaccumulation Potential: Low potential due to low log Kow
Mobility in Soil: High mobility, substance can permeate soils
Other Adverse Effects: Avoid release to environment, toxic to aquatic organisms
Waste Treatment Methods: Collect and contain waste, avoid discharge to natural water systems
Disposal of Product: Dispose of in accordance with local, national and international laws; incineration preferred in approved facility
Contaminated Packaging: Empty containers should be rinsed and then disposed of as hazardous waste
Special Precautions: Do not mix with other waste streams, label materials for chemical content clearly
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (Perhydroazepine)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III
Marine Pollutant: Yes
Special Transport Precautions: Keep containers upright and secure, follow emergency response guidance, segregate from incompatible materials
OSHA: Classified hazardous under OSHA Hazard Communication Standard (29 CFR 1910.1200)
EPA: Listed toxic chemical subject to SARA Title III Section 313
TSCA: Listed on the TSCA Inventory
REACH: Registered substance, subject to restrictions under EU REACH Regulation
Labeling Requirements: Use GHS pictograms, hazard statements, precautionary statements as outlined
Other Regulations: Compliance required with state, national, and international transport, storage and use regulations
