Material Safety Data Sheet: P-(1-Piperazinyl)Phenol

Identification

Product Name: P-(1-Piperazinyl)Phenol
Chemical Formula: C10H14N2O
Synonyms: 4-(1-Piperazinyl)phenol, Para-Piperazinylphenol
CAS Number: 13081-17-7
Recommended Use: Research, chemical synthesis, intermediate
Manufacturer: Contact details provided upon request
Emergency Phone Number: Available 24 hours

Hazard Identification

Classification: Acute Toxicity (oral & dermal), Skin Corrosion/Irritation, Serious Eye Damage/Irritation
Label Elements: GHS pictograms: exclamation mark, corrosion
Signal Word: Warning
Hazard Statements: Causes skin irritation; may cause serious eye irritation; harmful if swallowed or absorbed through skin; may cause respiratory irritation
Precautionary Statements: Do not breathe dust or fumes; wash hands thoroughly after handling; use in a well-ventilated area; wear protective gloves, protective clothing, and eye protection
Other Hazards: Dust can cause respiratory tract irritation; prolonged or repeated exposure may cause allergic reactions.

Composition / Information on Ingredients

Chemical Identity: P-(1-Piperazinyl)Phenol
CAS Number: 13081-17-7
Concentration: 100% by weight
Impurities/Additives: None known

First Aid Measures

Inhalation: Move exposed person to fresh air quickly; keep airway clear; if breathing becomes difficult, get immediate medical attention
Skin Contact: Remove all contaminated clothing; wash thoroughly with soap and plenty of water for at least 15 minutes; consult a physician if irritation develops
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present; continue rinsing and seek medical attention
Ingestion: Rinse mouth; avoid inducing vomiting unless directed by medical personnel; consult a physician immediately
Most Important Symptoms: Burning, redness, pain, irritation to eyes or skin, difficulty breathing

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Unsuitable Media: Do not use strong water jet
Special Hazards: Toxic gases such as oxides of nitrogen and carbon may be produced under fire
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Use water spray to cool containers exposed to heat or flame; avoid inhalation of combustion products

Accidental Release Measures

Personal Precautions: Evacuate area if necessary; ventilate area well; wear suitable protective clothing, gloves, and eye/face protection
Environmental Precautions: Prevent contamination of soil, surface water and groundwater; avoid discharge into the environment
Cleanup Methods: Absorb with inert material such as sand or vermiculite; sweep up and place in appropriate waste container for disposal; flush spill area with water after material removal

Handling and Storage

Handling: Use local exhaust ventilation to reduce dust/vapor formation; avoid contact with skin, eyes, and clothing; do not breathe dust or fumes; wash thoroughly after handling
Storage: Store in a tightly closed container in a cool, dry, well-ventilated place; keep away from incompatible substances such as strong oxidizers; avoid storage temperatures above room temperature
Incompatibilities: Strong acids, bases, oxidizing agents

Exposure Controls and Personal Protection

Exposure Limits: No specific occupational exposure limit established
Engineering Controls: Work in fume hood or with local exhaust extraction; ensure eyewash stations and safety showers are easily accessible
Personal Protective Equipment:

  • Respiratory protection: Suitable mask if ventilation is insufficient or exposure is possible
  • Hand protection: Chemical-resistant gloves (nitrile recommended)
  • Eye protection: Safety goggles or face shield
  • Skin and body protection: Wear lab coat or protective suit as needed
Hygiene Measures: Do not eat, drink, or smoke during work; wash hands after handling

Physical and Chemical Properties

Form: Solid or crystalline powder
Color: White to off-white
Odor: Slight, amine-like
Melting Point: 190–195°C
Boiling Point: Decomposes
Solubility: Soluble in water and some organic solvents
pH: Not determined
Vapor Pressure: Not determined
Relative Density: Not determined
Flash Point: Not available
Partition Coefficient: Not available
Flammability: May be combustible at high temperature

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with acids, strong oxidizers, or reducing agents
Conditions to Avoid: High temperature, sparks, open flames, humidity
Incompatible Materials: Strong acids, bases, oxidizing materials
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, other toxic fumes
Polymerization: No hazardous polymerization expected

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Causes skin and eye irritation; harmful if ingested or absorbed
LD50/LC50: Data for mammalian toxicity limited; handle as potentially harmful
Chronic Effects: Prolonged exposure may lead to sensitization; can provoke dermatitis or allergic reactions
Symptoms: Burning sensation, cough, shortness of breath, rash or redness, eye pain
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Other Effects: Sensitization possible in some individuals

Ecological Information

Ecotoxicity: Information on aquatic and terrestrial toxicity is limited; potential risk to organisms in case of large spill
Persistence and Degradability: Likely to degrade over time under environmental conditions, but specific rates unknown
Bioaccumulative Potential: Unknown, but molecule does not appear to bioaccumulate significantly
Mobility in Soil: Expected to be moderately mobile
Other Adverse Effects: Avoid uncontrolled release to the environment; collect and dispose efficiently

Disposal Considerations

Waste Treatment Methods: Dispose according to local, regional, and national regulations
Chemical Waste: Incinerate in a chemical incinerator equipped with a scrubber system; avoid discharge to sewers or watercourses
Contaminated Packaging: Remove residue and send to an approved waste disposal facility
Special Precautions: Wear protective equipment during handling of waste and cleanup of any residual material

Transport Information

UN Number: Not classified as a hazardous material for transport
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not classified for transport regulations
Special Precautions: Protect from physical damage, moisture, and extreme temperatures during transit; ship in well-sealed and labeled containers

Regulatory Information

OSHA Status: Not specifically regulated
TSCA Inventory: Listed or eligible
SARA 313: Not subject to reporting
Clean Air Act: Not regulated as a hazardous air pollutant
California Proposition 65: Substance not listed
Other Regulations: Follow all relevant regulations for handling, transportation, and disposal of chemical substances; consult national and local authorities for additional details.