Product Name: 2-Amino-5-Nitrothiazole
Synonyms: 5-Nitro-2-thiazolamine
Chemical Formula: C3H3N3O2S
CAS Number: 121-66-4
Intended Use: Laboratory chemicals, research use only
Manufacturer: Contact manufacturing label for address and phone number
Emergency Contact: Refer to regional poisonous control center or manufacturer emergency hotline listed on container
Recommended Uses: Research, pharmaceutical intermediate, chemical synthesis
GHS Classification: Acute toxicity (Oral, Category 4), Eye irritation (Category 2A), Skin irritation (Category 2)
Label Elements: Signal word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Precautionary Statements: Wash hands after handling, avoid inhalation of dust, avoid eye and skin contact, do not eat or drink while using
Hazard Symbols: Exclamation mark
Pictograms: Health hazard icon, exclamation mark
Chemical Name: 2-Amino-5-nitrothiazole
Concentration: ≥99% (for pure lab grade)
CAS Number: 121-66-4
EC Number: 204-485-4
Formula: C3H3N3O2S
Other Components: No significant additives reported
Impurities: Information on traces of moisture or related thiazole compounds in technical-grade forms available from supplier data
Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical advice if symptoms show up
Skin Contact: Remove contaminated clothing, wash skin with soap and water for several minutes, consult doctor if irritation starts
Eye Contact: Rinse eyes with water carefully for at least 15 minutes, take out contact lenses if present and simple to do, check with physician if any redness or pain continues
Ingestion: Rinse mouth, do not induce vomiting, drink water if able, take affected person to medical care without delay
Suitable Extinguishing Media: Dry chemical, CO₂, foam, water spray
Specific Hazards: Combustion generates toxic gases like nitrogen oxides, sulfur oxides
Advice for Firefighters: Wear self-contained breathing apparatus and full protective clothing, stay upwind, avoid inhaling fumes
Unusual Fire Hazards: Powder can disperse in air and increase burning speed, fire may produce irritating, corrosive or toxic gases
Personal Protection: Wear gloves, goggles, lab coat, dust mask or respirator
Spill Clean-Up: Avoid dust formation, clean up spills immediately with absorbent material, ventilate area, collect waste in sealed container
Environmental Precautions: Prevent product from entering drains, surface water, soil
Dissolution: Use damp paper or spill mats, never sweep dry powder
Safe Handling: Use inside fume hood if possible, avoid breathing dust, wear proper lab safety gear, wash hands after using, avoid smoking or eating around chemical
Storage Conditions: Keep in tightly closed original container, store cool and dry, keep away from incompatible materials like strong oxidizers and acids
Special Storage Considerations: Protect from heat, direct sunlight, and moisture, store away from possible ignition sources
Exposure Limits: No workplace exposure limits established; handle as if hazardous
Engineering Controls: Use with exhaust ventilation or in chemical fume hood
Eye/Face Protection: Chemical splash goggles recommended
Skin Protection: Lab gloves made of nitrile, lab coat or overalls
Respiratory Protection: Mask for dust protection or approved respirator
Hygiene Measures: Wash hands and face after working, avoid touching face with contaminated gloves
Appearance: Pale yellow to light brown crystalline powder
Odor: Odorless or faint chemical odor
Molecular Weight: 145.14 g/mol
pH (aqueous solution): Not available (low solubility)
Melting Point: 200–205°C
Boiling Point: Not measured (decomposes before boiling)
Solubility: Slightly soluble in water, more in ethanol, acetone
Flash Point: Not established
Vapor Pressure: Negligible at room temperature
Density: About 1.7 g/cm³
Partition Coefficient (log Kow): Not established
Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong acids, bases, oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids
Decomposition: Thermal decomposition can release nitrogen oxides, sulfur oxides
Polymerization: Not expected to occur
Hazardous Products of Decomposition: Toxic, irritating fumes may form if burning
Likely Routes of Exposure: Skin contact, eye contact, inhalation, ingestion
Acute Toxicity Data: Oral LD50 (rat): 970 mg/kg
Skin: Potential to cause irritation or allergic reaction
Eyes: Irritating to eyes, causes redness, pain
Inhalation: May irritate mucous membranes, coughing possible
Chronic Effects: No major long-term human studies, possible effects on blood and liver reported in animals
Symptoms of Overexposure: Headache, dizziness, skin rash, disturb vision, breathing difficulty
Carcinogenicity: No classification by IARC, NTP, or OSHA
Mutagenicity: Test data suggest possible genetic harm at high doses in animals (not definitive in humans)
Ecotoxicity: Toxic to aquatic life, especially fish and invertebrates
Persistence and Degradability: Not readily biodegradable, persists in environment
Bioaccumulative Potential: Data not conclusive, but considered moderate due to structure
Mobility: Compound not highly mobile in soil
Other Adverse Effects: Potential water pollutant, mitigate runoff from labs or facilities
Waste Treatment Methods: Dispose as hazardous chemical waste through licensed firm
Container Disposal: Clean, label as hazardous, seal, return to hazardous waste handler
Environmental Precautions: Do not release into sewers, soil, or waterways
Special Precautions: Avoid generating dust during disposal, reference local and national regulations for incineration or chemical destruction
UN Number: Not regulated under international transport codes (ADR, IATA, IMDG), confirm with shipper for large quantities
Proper Shipping Name: Not assigned, ship as “Chemical, N.O.S. (2-Amino-5-nitrothiazole)”
Packaging Group: Not classified for transport hazard
Precautions for Transport: Protect container from vibration, damage; avoid high temperatures, shield from direct sunlight
Transport Labeling: Include general chemical hazard labeling, follow internal site protocols for research chemicals
Inventory Listings: Registered in EINECS (EU), TSCA (US), DSL (Canada)
Workplace Regulations: OSHA Hazard Communication Standard applies in US
Labeling: Follow GHS guidelines, include hazard and safety phrases
Restrictions: Key restrictions for medical, agricultural, or food use apply unless specifically approved
Other Regulations: Safety management systems, local/national chemical control acts, personal exposure monitoring may apply in some settings
