Product Name: Nicotine Sulphate Solution
Synonyms: Nicotine sulfate, Nicotine dichloride sulfate
Chemical Formula: C10H14N2·H2SO4
CAS Number: 65-30-5
EC Number: 200-609-3
Intended Use: Used as insecticide in agriculture; possible laboratory reagent
Manufacturer: Listed by supplier with full address, contact phone, and emergency contact
Recommended Restrictions: For trained professionals; not for general household use
Emergency Overview: Highly toxic, severe health risks upon skin or eye contact, ingestion, or inhalation
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation) – Category 1; Eye Irritation – Category 2; Aquatic Acute Toxicity – Category 1
Signal Word: Danger
Hazard Statements: Fatal if swallowed; fatal in contact with skin; fatal if inhaled; causes serious eye irritation; very toxic to aquatic life
Pictograms: Skull and crossbones, exclamation mark, environmental hazard
Precautionary Statements: Avoid breathing vapors, wear protective gloves, do not eat or drink around product, keep away from water sources, wash hands thoroughly after use
Symptoms of Exposure: Headache, nausea, dizziness, sweating, abdominal pain, confusion, convulsions, respiratory failure
Routes of Entry: Inhalation, ingestion, ocular contact, skin absorption
Chronic Effects: Risk of neurological damage, mood disturbances, increased sensitivity to tobacco
Chemical Name: Nicotine sulfate
Concentration: Technical product typically 40%–60% nicotine sulfate in water
Other Ingredients: Water for dilution
Impurities: Possible trace organic solvents or stabilizers depending on source
Inhalation: Remove to fresh air immediately, provide oxygen if breathing difficulty develops, call a physician quickly
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, do not delay, seek emergency medical assistance
Eye Contact: Flush eyes with running water for at least 15 minutes lifting eyelids periodically, medical attention required
Ingestion: Do not induce vomiting, wash mouth and give large amounts of water if victim is fully conscious, medical treatment immediately
Emergency Advice: Always call certified poison control center and medical emergency team after exposure
Most Important Symptoms: Muscle twitching, respiratory distress, possible cardiac arrest
Special Instructions for Providers: Atropine recommended as antidote support in hospital settings
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Unsuitable Media: Direct water jet on burning liquid
Hazards from Combustion: Toxic fumes including nitrogen oxides, sulfur oxides, carbon monoxide, and carbon dioxide
Personal Protective Equipment: Chemical protective suit, positive pressure self-contained breathing apparatus
Firefighter Precautions: Avoid runoff into water sources
Specific Hazards: Heating above boiling point increases pressure, may cause packaging rupture
Special Procedures: Move containers from fire area if safe, cool containers with water fog
Personal Protection: Chemical-resistant gloves, long sleeves, eye protection, use of certified respirator
Spill Cleanup Methods: Ventilate area, absorb spill with earth, sand, or inert material, collect in sealable container
Decontamination: Wash residues with diluting soap solution, neutralize with dilute acid
Environmental Protection: Prevent product from entering waterways, drains, soil
Disposal of Collected Material: Follow local hazardous waste regulations
Notification Procedures: Report large spills to local safety and environmental authorities immediately
Safe Handling Practices: Use in well-ventilated area, do not smoke, eat, or drink while handling, keep containers tightly closed
Techniques to Reduce Risks: Handle away from ignition sources and oxidizing agents
Storage Recommendations: Store locked, away from food, feed, incompatible materials, and sunlight; controlled temperature between 2°C and 8°C
Container Guidelines: Use corrosion-resistant, non-reactive containers, ensure proper labeling, secondary containment recommended
Segregation: Keep away from alkaline substances, reducing agents
Occupational Exposure Limits: ACGIH TLV: 0.5 mg/m3 (skin), OSHA PEL not set
Engineering Controls: Fume hood or local exhaust ventilation
Eye Protection: Safety goggles, face shield
Hand Protection: Nitrile or neoprene gloves, frequent changes for splash potential
Body Protection: Impervious apron or coveralls, chemical sleeves if risk of splash
Respiratory Protection: Full-face respirator (organic vapor/acid gas cartridge), or supplied-air respirator for high concentration
Hygiene Measures: Wash thoroughly after handling, separate contaminated clothing
Appearance: Clear to pale yellow liquid
Odor: Characteristic, pungent, tobacco-like
pH: ~4–5 (10% aqueous solution)
Boiling Point: Water-based solution above 100°C
Melting Point: Not applicable to solution
Solubility: Miscible in water
Density: 1.05–1.10 g/cm3 (solution)
Vapor Pressure: Not significant at room temperature
Flash Point: Above 60°C (solution, though pure nicotine is much lower)
Autoignition Temperature: Not easily ignited in aqueous form
Explosive properties: Not explosive in standard solution
Partition Coefficient (log Kow): -0.8 to -1.1 (nicotine)
Chemical Stability: Stable under standard conditions
Reactivity: Reacts strongly with oxidizing agents, bases
Thermal Decomposition: Decomposes to produce toxic nitrogen oxides, sulfur oxides, and possibly hydrogen cyanide at high temperatures
Avoid Storage Conditions: Do not store near acids, alkalis, oxidizers, or in sunlight
Hazardous Reactions: Polymerization does not occur under normal conditions
Incompatibilities: Alkali metals, strong acids, alkalis, oxidizers
Acute Toxicity: Oral LD50 (rat): 50 mg/kg; Dermal LD50 (rabbit): 285 mg/kg
Inhalation: LC50 (rat): ~1.0 mg/L (4h)
Chronic Toxicity: Prolonged exposure damages central nervous system, cardiovascular system
Irritation: Skin, mucous membrane, eye irritation likely
Sensitization: Can cause allergic reactions in sensitive individuals
Mutagenicity: Not classified as mutagenic based on available studies, but caution urged
Carcinogenicity: IARC, EPA: Not classified as carcinogen; data insufficient for solutions
Specific Target Organ Toxicity: Central nervous system, respiratory system, cardiovascular system
Other Effects: Convulsions, respiratory paralysis, death at high doses
Aquatic Toxicity: Very toxic to aquatic life, LC50 (fish, 96h): 6–8 mg/L (nicotine base)
Bioaccumulation Potential: Low persistence, moderate bioaccumulation possible
Degradation: Nicotine degrades in open environment but hazardous to aquatic organisms until fully degraded
Soil Mobility: Mobile in soil, risk of groundwater contamination
Other Effects: Harmful to terrestrial invertebrates and pollinators at field concentrations
Precautions: Prevent entry into soil, surface, and groundwater; limit agricultural runoff
Disposal Methods: Burn in a chemical incinerator equipped with afterburner and scrubber; do not landfill or pour into sewer
Sludge and Container Disposal: Rinse all equipment and containers three times; collect rinsate for hazardous waste disposal
Regulatory Guidance: Dispose in accordance with federal, local, and state hazardous waste regulations
Do Not Reuse Containers: Once emptied, containers must be punctured and rendered unusable
Remediation: Use professional waste contractors certified for toxic pesticide disposal
UN Number: 1654 (Nicotine compounds, liquid, toxic, n.o.s.)
Proper Shipping Name: Nicotine sulfate solution
Hazard Class: 6.1 (Toxic substances)
Packing Group: I
Labeling: Toxic symbol, correct shipping name, hazard identification number
Transport Method: Certified carriers with trained personnel only
Special Precautions: Avoid transport through populated areas, prevent package drop/rupture
Environmental Hazards: Mark as marine pollutant for sea transportation
Emergency Response Guide: Refer to chemical emergency guidebook number 151
OSHA Status: Classified as hazardous chemical by Hazard Communication Standard
EPA Status: Registered under Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)
SARA Title III: Listed as Extremely Hazardous Substance, subject to reporting requirements
TSCA: Listed in Toxic Substances Control Act inventory
DSL/NDSL: Present on Canadian Domestic Substances List
WHMIS Classification: D1A – Very toxic material causing immediate and serious toxic effects
EU Classification: T+, N (Very toxic; Dangerous for the environment)
Other Regulatory Info: Subject to country-specific pesticide regulations, export controls apply, packaging and transport must comply with Hazardous Materials regulations
