Product Name: N-Phenylpiperazine
CAS Number: 92-54-6
Other Names: 1-Phenylpiperazine, NPP
Recommended Use: Chemical intermediate, laboratory research
Manufacturer: (Not specified)
Contact Information: Supplier or laboratory chemical provider
Emergency Phone Number: Consult local emergency services
Classification according to GHS: Acute Toxicity (Oral, Dermal, Inhalation), Eye Irritation, Skin Irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, harmful in contact with skin, causes skin irritation, causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust/fume/gas/mist/vapors/spray, use protective gear, wash exposed skin thoroughly after handling, avoid release into the environment.
Potential Health Effects: Can irritate eyes, skin, and respiratory system; ingestion may produce symptoms such as nausea, dizziness, headache.
Chemical Name: N-Phenylpiperazine
Purity: Typically >98%
Molecular Formula: C10H14N2
Molecular Weight: 162.23 g/mol
Impurities: May contain trace piperazine-related compounds
General Advice: Move affected person away from source, remove contaminated clothing
If Inhaled: Move person into fresh air, keep at rest, seek medical attention if symptoms persist
If On Skin: Wash immediately with soap and plenty of water, remove contaminated clothing, seek medical help for persistent symptoms
If In Eyes: Flush with large quantities of water for several minutes, lift eyelids occasionally, get medical attention
If Ingested: Do not induce vomiting, rinse mouth out, seek immediate medical assistance
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water jets
Special Hazards: Fire or heat may produce hazardous decomposition products such as nitrogen oxides, carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Firefighting Advice: Stay upwind, avoid inhaling fumes, cool containers exposed to heat with water
Personal Precautions: Use appropriate personal protective equipment, avoid dust formation, ensure adequate ventilation, evacuate unnecessary personnel
Environmental Precautions: Prevent entry into drains, surface water, and soil
Containment Methods: Sweep up and place in a suitable container for disposal, avoid creating dust, ventilate the area
Cleanup Procedures: Wash area with soap and water, dispose of contaminated material in accordance with local regulations
Safe Handling Instructions: Wear suitable protective clothing and gloves, avoid inhalation of dust, prevent contact with eyes and skin, wash hands after use
Storage Conditions: Keep container tightly closed in a cool, dry, and well-ventilated place, store away from incompatible substances
Special Storage Requirements: Protect from light, humidity, and sources of ignition, store in original packaging
Exposure Limits: No occupational exposure limits established for this compound
Engineering Controls: Ensure proper ventilation, use local exhaust if available
Personal Protective Equipment: Use gloves resistant to chemicals, safety glasses or goggles, protective clothing, use approved respirator for dust or vapor exposure
Hygiene Measures: Wash hands, face, and exposed skin after handling, do not eat or drink during work, remove contaminated clothing before reuse
Physical State: Crystalline powder or solid
Color: White to off-white
Odor: Weak, characteristicamine
Melting Point: 56–58°C
Boiling Point: 260–270°C
Solubility: Soluble in common organic solvents, slightly soluble in water
Vapor Pressure: Not available
Density: 1.07—1.10 g/cm³
pH: Not applicable
Flash Point: >110°C
Auto-Ignition Temperature: Not established
Partition Coefficient (log Kow): Estimated around 2
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not highly reactive under normal conditions
Conditions to Avoid: Excess heat, open flames, moisture
Incompatible Materials: Strong oxidizing agents, strong acids
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: Will not occur under normal handling
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: May cause irritation and symptoms such as headache, dizziness, faintness, gastrointestinal upset
Skin Corrosion/Irritation: Causes irritation to skin
Serious Eye Damage/Irritation: Causes severe eye irritation
Respiratory Sensitization: Not classified as a sensitizer
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity: Data limited; not considered mutagenic in standard tests
Reproductive Toxicity: No data suggesting reproductive hazards
Chronic Effects: Prolonged exposure not expected to cause long-term health effects based on animal data
Symptoms of Overexposure: Burning eyes, dermatitis, respiratory discomfort, nausea
Ecotoxicity: Can be toxic to aquatic life at higher concentrations
Mobility in Soil: Limited data available, expected low mobility, may adsorb to soil
Persistence and Degradability: May degrade slowly in the environment
Bioaccumulative Potential: Low to moderate potential based on log Kow values
Additional Advice: Avoid release to surface waters or sewers
Product Disposal: Dispose in accordance with local, regional, and national regulations, use an approved waste disposal contractor
Contaminated Packaging: Empty containers should be rinsed and disposed as hazardous waste
Waste Codes: Consult applicable environmental authority for allocation
Avoid: Discharge into drains, watercourses, or onto the ground
UN Number: Not regulated for transport according to current regulations
Proper Shipping Name: N-Phenylpiperazine
Transport Hazard Class(es): Not classified as dangerous
Packing Group: Not assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions for User: Avoid spills and container damage, secure transport packaging
TSCA: Listed in the United States Toxic Substances Control Act inventory
REACH: Registration or notification may apply in the EU
OSHA: Not specifically regulated
SARA Title III: Not listed as a reportable hazardous chemical
Canada DSL/NDSL: Present on the Domestic Substances List
Other Requirements: Always check country-specific regulations for handling, storage, and disposal
