Product Name: N,N'-Bis(3-Aminopropyl)Piperazine
Chemical Formula: C10H24N4
CAS Number: 6940-57-4
Synonyms: 1,4-Piperazinedi(propan-1-amine), BAPP
Use: Intermediate for epoxy curing, surfactants, corrosion inhibitors
Manufacturer: Refer to supplier documentation for details
Contact Details: Emergency phone and supplier contact as provided on purchase invoice
Hazard Classification: Corrosive to skin and eyes, Harmful if inhaled or swallowed
Label Elements: Danger — Causes severe burns, Possible respiratory irritation
Pictogram: Corrosive (GHS05), Exclamation (GHS07)
Signal Word: Danger
Hazard Statements: H302: Harmful if swallowed; H314: Causes severe skin burns and eye damage; H332: Harmful if inhaled
Precautionary Statements: Wear protective gloves/clothing/eye/face protection; Do not breathe vapor or mist; Wash skin and hands thoroughly after handling
Health Hazards: Strong mucous membrane irritant, May cause burns and irreversible eye damage
Environmental Hazards: Harmful to aquatic life with long lasting effects
Chemical: N,N'-Bis(3-Aminopropyl)Piperazine
CAS Number: 6940-57-4
Percentage: 98–100% (by weight)
Impurities: Typical trace amounts of piperazine and other amines
EC Number: 230-949-8
Molecular Weight: 200.33 g/mol
Inhalation: Remove to fresh air. Keep at rest. Seek medical advice right away if symptoms like coughing or shortness of breath appear.
Skin Contact: Remove contaminated clothing. Wash thoroughly with soap and plenty of water. Get medical help immediately if irritation persists or blisters develop.
Eye Contact: Rinse continuously with water for at least 15 minutes, holding eyelids apart. Remove contact lenses if easy. Get emergency medical attention—damage can occur quickly.
Ingestion: Rinse mouth out with water. Do not induce vomiting. Have victim drink water. Never give anything by mouth to an unconscious person. Contact Poison Center or doctor immediately.
Medical Attention Notes: Treat symptomatically for corrosive injuries. Pay close attention to potential delayed respiratory effects.
Suitable Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable Media: Do not use high-pressure water directly on burning substance to prevent spattering.
Hazards: During combustion, toxic fumes of nitrogen oxides, ammonia and carbon oxides can form.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Special Procedures: Move containers away from fire zone if safe. Stay upwind and avoid inhaling vapors.
Personal Precautions: Use chemical splash goggles, rubber or nitrile gloves, chemical resistant clothing. Avoid skin and eye contact.
Environmental Precautions: Prevent spill from entering drains, water courses, or soil. Notify appropriate regulatory authorities in the event of significant spill.
Cleanup Methods: Absorb small spills with inert material (sand, earth, vermiculite). Place in chemical waste containers with tight seals.
Large Spills: Dike far ahead of liquid spill for later collection. Use non-sparking tools and ventilate area. Wash area with water after pick-up.
Handling: Avoid breathing vapor or mist. Prevent skin and eye exposure by wearing appropriate PPE. Use only in well-ventilated areas. Change contaminated clothing and wash before reuse.
Storage Conditions: Store in tightly closed containers away from strong acids, oxidizers, and food. Keep in a cool, dry, well-ventilated location.
Incompatibility: Acids, oxidizing agents, anhydrides, strong halogens.
Other Precautions: Do not store near incompatible materials. Label all containers clearly and keep them tightly sealed.
Occupational Exposure Limits: No established OSHA or ACGIH limits for this compound; keep airborne concentrations as low as possible.
Engineering Controls: Use fume hoods, local exhaust, or process enclosure to minimize exposure.
Personal Protective Equipment: Butyl or nitrile gloves, chemical goggles, face shield, long sleeve clothing. In emergencies or where exposure limits are exceeded, use NIOSH approved respirator.
Hygiene: Wash hands, arms, and face before eating, drinking, or leaving work area. Avoid reused or contaminated clothing.
Appearance: Colorless to pale yellow liquid (sometimes slightly viscous)
Odor: Amine-like, strong; unpleasant at high concentrations
Odor Threshold: No reliable data
pH: Alkaline (measured at 10 g/l H2O, 20°C)
Melting Point: < -20°C
Boiling Point: 166–170°C at 20 mmHg
Flash Point: 145°C (closed cup)
Evaporation Rate: Not available
Flammability: Not classified as flammable, but can burn if preheated
Vapor Pressure: 0.13 hPa @ 20°C
Vapor Density: Heavier than air (estimated)
Solubility: Fully miscible in water, soluble in polar organic solvents
Partition Coefficient (log Kow): Lower than 1 (high water solubility)
Auto-ignition Temperature: ~335°C
Decomposition Temperature: Begins to decompose above 200°C
Viscosity: Moderate, temperature dependent
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Excessive heat, sparks, open flames, contact with incompatible chemicals
Polymerization: Not known to polymerize under normal conditions
Incompatible Materials: Acids (may cause violent reaction), strong oxidizers (risk of fire), acid anhydrides, halogen-containing compounds
Hazardous Decomposition: Nitrogen oxides, ammonia, carbon monoxide, carbon dioxide if heated or burned
Reactivity: Strong base, can react exothermically with acids and some metals
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity (Oral): LD50 rat: 2,000–4,000 mg/kg
Acute Toxicity (Dermal): LD50 rat: >2,000 mg/kg
Acute Toxicity (Inhalation): Harmful if inhaled; nose and throat irritation, potential lung damage at high levels
Skin Corrosion/Irritation: Causes severe burns within minutes
Serious Eye Damage/Irritation: Causes severe eye damage and possible blindness
Respiratory Sensitization: May cause airway irritation, bronchospasm in sensitive individuals
Skin Sensitization: Not classified as sensitizing, but repeated contact increases risk
Carcinogenicity: No reliable studies show carcinogenicity in animals or humans
Mutagenicity: No evidence based on available data
Reproductive Toxicity: No significant effects identified in animal studies
Environmental Fate: Readily soluble in water, low expected persistence in soil
Ecotoxicity: Harmful to aquatic life
Acute Toxicity to Fish: LC50 (96h, fish): 180 mg/l
Aquatic Invertebrates: EC50 (48h, Daphnia): 32 mg/l
Aquatic Plants: EC50 (72h, algae): 55 mg/l
Biodegradability: Moderately biodegradable, not persistent under aerobic conditions
Bioaccumulation: Low potential due to high water solubility and low log Kow
Other Adverse Effects: No data on ozone depletion, global warming, or photochemical ozone creation
Waste Treatment Methods: Dispose of via licensed chemical waste contractor
Contaminated Packaging: Rinse thoroughly and send for specialist disposal as hazardous waste
Disposal Restrictions: Do not pour into drains, sewers, or water sources
Appropriate Disposal: Collect waste in clearly labeled, sealed containers for incineration or chemical treatment
Special Precautions: Follow all local, regional, and national regulations for hazardous waste
UN Number: UN 2734
UN Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (contains N,N'-Bis(3-Aminopropyl)Piperazine)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: II
Marine Pollutant: Not classified as marine pollutant under current regulations
Transport Labels: Corrosive (Class 8)
Special Precautions for Users: Use certified corrosion-resistant containers, avoid transfer near food or reactive chemicals, emergency response guides available
Additional Information: National and international guidelines (ADR, RID, IMDG, IATA) apply in full
Classification: Regulated under OSHA Hazard Communication Standard
TSCA (US): Listed
REACH (EU): Substance registered; refer to ECHA info
DSL (Canada): Listed
Other Inventories: Included in Australia (AICS), Korea (KECI), China (IECSC), Japan (ENCS)
Other Regulations: Subject to workplace exposure regulations for corrosive and toxic chemicals
Risk Phrases: R22 (Harmful if swallowed), R34 (Causes burns)
Safety Phrases: S26 (In case of contact with eyes, rinse immediately), S36/37/39 (Wear suitable protective clothing/gloves/eye/face protection), S45 (In case of accident, seek medical advice immediately)
