Product Name: N,N,2,2,6,6-Hexamethyl-4-Piperidinamine
CAS Number: 34462-75-6
Chemical Formula: C11H26N2
Molecular Weight: 186.34 g/mol
Synonyms: 4-Piperidinamine, N,N,2,2,6,6-hexamethyl-
Recommended Use: Intermediate in chemical synthesis, stabilizer in polymer manufacturing, light stabilizer in coatings and plastics industries
Manufacturer/Supplier: Listed per local requirement
Emergency Contact: Refer to local or supplier emergency phone number
GHS Classification: Acute Toxicity Category 4 (Oral, Dermal); Skin Corrosion Category 1B; Serious Eye Damage Category 1; Aquatic Chronic Category 2
Hazard Statements: Harmful if swallowed or absorbed through skin. Causes severe skin burns and eye damage. Toxic to aquatic life with long lasting effects.
Pictograms: Corrosive, Exclamation mark, Environment
Signal Word: Danger
Precautionary Statements: Avoid breathing dust, fumes, gas, mist, vapors, or spray. Wash hands thoroughly after handling. Wear protective gloves, protective clothing, eye protection, and face protection.
Routes of Exposure: Inhalation, ingestion, skin, and eyes. Direct contact brings risk of severe burns. Inhalation can cause respiratory irritation. Environmental spills risk harm to aquatic systems.
Chemical Name: N,N,2,2,6,6-Hexamethyl-4-Piperidinamine
Concentration: ≥98%
Impurities: Trace quantities of homologous amines and residual starting materials—less than 2% total
Component CAS Number: 34462-75-6
TSCA Status: Listed or compliant
Other Components: No significant stabilizers, diluents, or solvents present beyond quality control limits
General: Remove contaminated clothing and shoes immediately and wash before reuse. Move person to fresh air and keep at rest in a position comfortable for breathing. Seek medical advice for all exposures.
Inhalation: Remove individual from exposure to fresh air. Provide oxygen if breathing is labored. Call a physician immediately if symptoms like respiratory irritation, coughing, or dizziness occur.
Skin Contact: Rinse immediately with plenty of water for at least 15 minutes. Remove contaminated clothing. Seek medical attention right away for burns or persistent irritation.
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting upper and lower eyelids occasionally. Remove contact lenses if present and easy to do. Always seek urgent ophthalmologic care.
Ingestion: Do not induce vomiting. Rinse mouth with water. Seek immediate professional medical help. Never give anything by mouth if the person is unconscious.
Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray (do not use direct high-pressure stream).
Specific Hazards: Decomposes on combustion to release toxic fumes including nitrogen oxides, ammonia, carbon monoxide, and carbon dioxide.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear to prevent contact with skin and eyes.
Firefighting Precautions: Approach upwind, keep containers cool with water spray. Avoid inhalation of hazardous combustion products.
Explosion Risk: No specific risk unless exposed to extreme temperatures; containers can burst if heated.
Personal Precautions: Evacuate personnel to safe areas. Wear adequate personal protection including nitrile gloves, chemical goggles, and lab coat or chemical-resistant suit.
Environmental Precautions: Prevent product from entering drains, surface water, or soil. Report spills to environmental authorities if required.
Containment Methods: Stop leakage, contain spill with absorbent material (sand or earth). Avoid contact with skin and eyes.
Cleanup Procedures: Shovel up and collect spilled material in sealable, labeled containers for appropriate disposal. Ventilate and wash contaminated area with water post-clean-up. Dispose of solid absorbents as hazardous waste.
Handling: Always use with local exhaust ventilation in space with eye wash station and safety showers. Avoid skin and eye contact, minimize aerosol and vapor generation. Separate from acids and oxidizers.
Storage: Store in tightly closed, properly labeled containers in a cool, dry, well-ventilated area. Protect from direct sunlight, ignition sources, and moisture. Use containers compatible with amines and resistant to corrosion.
Incompatible Materials: Oxidizing agents, strong acids, halogenated compounds, acid anhydrides. Avoid proximity to food and feedstuffs.
Occupational Exposure Limits: No OSHA or ACGIH exposure standard specified. Use best industrial hygiene practices; minimize exposure.
Engineering Controls: Proper mechanical ventilation, fume hood, or process enclosure where feasible.
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile, butyl rubber), safety goggles, face shield, impermeable clothing, and protective footwear.
Respiratory Protection: Respirator suitable for organic vapors and amines in areas of insufficient ventilation.
Hygiene Measures: Wash thoroughly after using, before eating, drinking, or smoking. Do not eat, drink, or smoke in handling area.
Appearance: Viscous, colorless to pale yellow liquid
Odor: Distinctive amine-like
Odor Threshold: Not measured
pH: Strongly basic in aqueous solution
Melting Point: 10 – 20 °C
Boiling Point: 265 – 270 °C at 1013 hPa
Flash Point: 133 °C (closed cup)
Evaporation Rate: Not determined
Flammability: Not easily flammable, but will burn at high temperatures
Vapor Pressure: <0.1 mmHg at 20 °C
Vapor Density: No established data
Density: 0.905 – 0.915 g/cm³ at 20 °C
Solubility: Miscible with water and common organic solvents
Partition Coefficient (log Kow): 1.9 (estimated)
Auto-Ignition Temperature: >300 °C
Decomposition Temperature: No data
Viscosity: Relatively high
Chemical Stability: Stable under normal conditions; reacts exothermically with acids and oxidizers.
Potentially Hazardous Reactions: Violent reaction possible with strong oxidants, acid chlorides, or acid anhydrides. Generates heat and toxic vapors with acids.
Conditions to Avoid: High temperature, sources of ignition, contact with strong acids or oxidizers.
Hazardous Decomposition Products: Nitrogen oxides, ammonia, carbon monoxide, carbon dioxide upon combustion or thermal decomposition.
Polymerization: Unlikely, not expected under normal storage or processing.
Acute Toxicity: Oral LD50 (rat): 1100 mg/kg. Dermal LD50 (rabbit): >2000 mg/kg.
Skin Corrosion/Irritation: Causes severe burns. Prolonged or repeated contact can result in dermatitis, ulceration.
Eye Damage/Irritation: Corrosive, risk of irreversible damage, severe conjunctival irritation, possible blindness.
Respiratory Sensitization: Vapors or mists may cause respiratory tract irritation, sore throat, difficulty breathing.
Skin Sensitization: Prolonged contact can cause allergic dermatitis in sensitized individuals.
Chronic Toxicity: No long-term animal studies available; chronic exposure risks severe local tissue damage.
Mutagenicity/Carcinogenicity: No evidence from standard assays or regulatory listings.
Other Health Effects: Central nervous system depression possible in severe cases of ingestion or large-scale absorption.
Aquatic Toxicity: LC50 (fish, 96 hr): 18 mg/L. EC50 (daphnia, 48 hr): 14 mg/L.
Persistence and Degradability: Moderately biodegradable. Product not readily degraded in soil and water.
Bioaccumulative Potential: Moderate by calculated log Kow values; expected for similar tertiary amines.
Mobility in Soil: High water solubility indicates potential for leaching; moderate risk for groundwater contamination.
Other Adverse Effects: Toxic at low concentrations for freshwater aquatic organisms. Product may raise pH in effluent streams, endangering aquatic life.
Waste Methods: Dispose according to local, regional, national, and international regulations. Incineration in approved facilities with flue gas scrubbing preferred for liquids and contaminated materials.
Container Disposal: Triple rinse with water, puncture or crush, and submit for industrial disposal. Do not dispose in municipal waste stream.
Special Precautions: Consider neutralization and pre-treatment before discharge if allowed. Responsibility for proper classification and risk assessment falls to generator and facility.
UN Number: 2734
UN Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (N,N,2,2,6,6-Hexamethyl-4-Piperidinamine)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Labeling Requirements: Corrosive (Class 8), Marine Pollutant if shipped in bulk
Special Transport Precautions: Secure containers upright, ensure proper signage and emergency response supplies accessible
Regulatory Status: Subject to DOT, IMDG, and IATA regulations for transport due to corrosivity and aquatic hazard;
Environmental Hazards: Marine pollutant under IMDG; avoid release to waterways
U.S. TSCA: Listed
OSHA Hazardous Chemical: Yes
SARA 313: Does not contain components that exceed threshold reporting levels
EPA CERCLA: Not reportable quantity chemical
EU REACH: Registered substance. Classified according to CLP Regulation EC 1272/2008
Canadian DSL: Listed
WHMIS Classification: D2B (skin and eye irritant), E (corrosive material)
Other National/Regional Listings: Consult country and local inventories for precise coverage and reporting rules.
Hazard Symbols: C (Corrosive), N (Dangerous for the environment)
