Material Safety Data Sheet: N-Methyl-4-Bromopiperidine

Identification

Product Name: N-Methyl-4-Bromopiperidine
Chemical Formula: C6H12BrN
CAS Number: 361440-67-9
Recommended Use: Laboratory chemical, research applications
Synonyms: 1-Methyl-4-bromopiperidine
Manufacturer: Refer to supplier or laboratory
Contact Number: Refer to supplier or laboratory contact list
Emergency Number: Refer to local or national poison control center

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal and inhalation), Skin and eye irritation
Hazard Pictograms: Skull and crossbones, exclamation mark
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin or inhaled; causes skin and eye irritation
Precautionary Statements: Avoid breathing dust or vapor, wash exposed skin thoroughly, use only outdoors or in well-ventilated area, wear suitable personal protective equipment, do not eat, drink or smoke while handling

Composition / Information on Ingredients

Substance: N-Methyl-4-Bromopiperidine
Chemical Family: Brominated heterocyclic amine
Purity: Typically >98% (verify batch-specific certificate)
Impurities: Trace amounts of related piperidine compounds or solvents

First Aid Measures

Inhalation: Move person to fresh air, seek medical attention if symptoms persist, provide artificial respiration if breathing is difficult
Skin Contact: Remove contaminated clothing, rinse skin with water for at least 15 minutes, consult a physician if irritation develops
Eye Contact: Immediately flush eyes with water for 15 minutes, lift eyelids to ensure thorough rinsing, get medical aid
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical assistance
Most Important Symptoms/Effects: Burning sensation, cough, breathing difficulty, nausea, redness or blistering of skin and eyes

Fire-Fighting Measures

Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder or alcohol-resistant foam, do not use water jet
Hazards: Can release toxic fumes including hydrogen bromide and nitrogen oxides during combustion
Protective Equipment: Wear self-contained breathing apparatus (SCBA) and full protective gear, keep away from confined spaces
Special Procedures: Cool unaffected containers with water spray, evacuate area if fire is severe or if toxic fumes are detected

Accidental Release Measures

Personal Precautions: Evacuate personnel, ventilate the area, use appropriate chemical-resistant gloves and eye/face protection, avoid skin contact
Environmental Precautions: Prevent further leakage or spillage, prevent product from reaching sewage, rivers or groundwater
Cleanup Methods: Absorb spills with inert material (such as sand or earth), place in chemical waste container, wash spill area with plenty of water, dispose of materials according to local regulations

Handling and Storage

Precautions for Safe Handling: Work in a well-ventilated hood, minimize dust or vapor formation, avoid direct contact, keep containers tightly closed
Storage Conditions: Store at room temperature in a dry, well-ventilated area, protected from light, incompatible materials include strong oxidizing agents and acids
Surveillance: Secure containers to prevent accidental opening, label clearly, keep away from untrained personnel

Exposure Controls and Personal Protection

Engineering Controls: Use exhaust ventilation or chemical fume hood, install eyewash stations and safety showers near work area
Personal Protective Equipment: Chemical-resistant gloves, laboratory coat, safety goggles, appropriate respirator for high vapor or dust concentrations
Hygiene Measures: Wash hands, arms and face after handling, do not eat, drink, or smoke until all exposures have been removed, launder contaminated clothing before reuse

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid or solid (depends on purity and temperature)
Odor: Amine-like, irritating
Melting Point: Information not widely available, approximate liquid at standard conditions
Boiling Point: Estimated 200-210°C at atmospheric pressure
Flash Point: Data unavailable, precautionary measures recommended
Solubility: Soluble in alcohol, moderate in water
Vapor Pressure: Data unavailable
Density: Estimated 1.3-1.4 g/cm³
pH: Not applicable as a solid, basic in solution

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, avoid moisture and air exposure
Reactivity: Reacts with strong oxidizers, acids, producing toxic gases
Decomposition Products: Nitrogen oxides, hydrogen bromide, possible carbon monoxide and carbon dioxide
Conditions to Avoid: Heat, sparks, open flames, incompatible chemicals

Toxicological Information

Routes of Exposure: Ingestion, inhalation, dermal, ocular
Acute Effects: Toxic if swallowed or absorbed through skin, causes irritation to mucous membranes, possible central nervous system effects
Chronic Effects: Long-term exposure may produce organ damage, respiratory or skin sensitization
Carcinogenicity: No data available for this compound
LD50/LC50: Not established in literature, use high degree of caution
Symptoms: Dizziness, headache, skin rashes, eye watering, respiratory distress, nausea, abdominal pain

Ecological Information

Aquatic Toxicity: Harmful to aquatic life, avoid uncontrolled environmental release
Persistence and Degradability: Limited environmental data, expected to persist due to stability
Bioaccumulation: Potential for bioaccumulation not fully investigated
Mobility in Soil: May leach, movement depends on site conditions

Disposal Considerations

Waste Treatment Methods: Dispose of as hazardous waste, consult local regulations
Container Disposal: Triple rinse empty containers, render them unusable, dispose of in accordance with regional protocols
Avoid: Disposal via drains, sewers or uncontrolled landfills

Transport Information

UN Number: Not assigned, treat as toxic organic chemical
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Labeling Requirements: Toxic substance, handle with care, mark package with hazard symbol
Additional Information: Avoid high temperature and accidental drops during transport

Regulatory Information

OSHA/IARC/NTP: Not specifically regulated, treat according to general industrial chemical standards
SARA Title III: Not listed
TSCA Status: Check supplier for TSCA compliance
EU Classification: Harmful; R22, R36/38 (toxic if swallowed, irritating to eyes and skin)
Reference: Always review workplace chemical safety protocols and consult with local regulatory authorities for additional requirements