Product Name: N-Boc-Pyrrole
Chemical Formula: C9H13NO2
Synonyms: N-tert-Butoxycarbonylpyrrole; Boc-protected pyrrole
Usage: Building block in organic synthesis, research laboratories
Physical Description: Off-white to pale yellow solid, mild characteristic odor
CAS Number: 72817-20-6
Manufacturer: Various chemical suppliers (Sigma-Aldrich, TCI, Alfa Aesar, etc.)
Emergency Contact: Refer to local supplier's emergency line, general chemical emergency number: CHEMTREC +1-800-424-9300
Classification: Not classified as hazardous, but can pose risk under improper conditions
GHS Label Elements: Not required for most users, though local regulations might require standard labeling
Hazards: May irritate eyes, respiratory system, and skin; avoid excessive inhalation and contact
Precautionary Statements: Wear suitable gloves and goggles; use in well-ventilated space; avoid eating or drinking near material
Common Name: N-Boc-Pyrrole
Chemical Identity: Pyrrole, 1-(tert-butoxycarbonyl)-
Concentration: >98% pure as typically supplied
Impurities: Trace organic byproducts possible from synthesis
Stabilizers: Not commonly present
Eye Contact: Wash thoroughly with water, holding lids open for several minutes; consult a doctor if irritation lasts
Skin Contact: Remove contaminated clothing, rinse skin with water and soap for at least 15 minutes
Inhalation: Move to fresh air, help breathing if needed, seek medical help for persistent discomfort
Ingestion: Rinse mouth, avoid inducing vomiting, contact poison control or medical service
Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide; avoid water jets
Fire Hazards: May emit toxic fumes like nitrogen oxides and carbon monoxide if burned
Protective Equipment: Firefighters use NIOSH-approved self-contained breathing apparatus and full protective clothing
Precautions: Remove all material from vicinity of fire if safe to do so, ventilate area
Personal Precautions: Wear gloves, safety glasses, dust mask or respirator
Spill Cleanup: Sweep or scoop up material without raising dust, place in a sealed container for disposal
Environmental Precautions: Prevent further leakage, avoid letting substance enter drains or waterways
Decontamination: Wash spill area with water and detergent after clean-up
Handling: Keep containers tightly closed; handle with gloves in well-ventilated fume hoods
Hygiene: Wash hands after handling; remove clothing that gets contaminated
Storage Conditions: Store at room temperature (15–25°C / 59–77°F) in dry, ventilated location away from heat, ignition sources
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Engineering Controls: Work in a chemical fume hood or with mechanical exhaust
Personal Protection: Gloves made of nitrile or neoprene, chemical splash goggles, lab coat or apron
Respiratory Protection: Use dust mask or respirator if ventilation is inadequate
Exposure Limits: No occupational exposure limits specified by OSHA, ACGIH, or NIOSH
Appearance: Off-white to pale yellow solid
Odor: Light, musty chemical smell
Melting Point: 46–52°C
Boiling Point: Not available (decomposes or sublimes before boiling)
Solubility: Slightly soluble in water; soluble in ethanol, dichloromethane, other organic solvents
Vapor Pressure: Not significant under standard conditions
Density: ~1.18 g/cm³
pH: Not applicable (non-aqueous solid)
Other Data: Stable in original packaging for months under recommended storage
Chemical Stability: Stable under recommended storage and handling
Hazardous Reactions: Reacts with strong oxidizers, acids; avoid contact with open flames and heat
Decomposition Products: May release nitrogen oxides, carbon monoxide, carbon dioxide if burned or heated strongly
Polymerization: Does not undergo hazardous polymerization
Acute Toxicity: No detailed LD50 data, low to moderate acute risk with large exposures
Routes of Entry: Eyes, skin, ingestion, inhalation
Symptoms: Irritation of eyes, skin, airways; possible headache, nausea if inhaled in large amounts
Chronic Exposure: No long-term data, but as with most lab chemicals, minimizing regular exposure makes sense
Carcinogenicity: No known data on cancer risk
Other Effects: No specific information available on mutagenicity or reproductive toxicity
Aquatic Toxicity: Data lacking, but most pyrrole derivatives present moderate risk to aquatic life if released in quantity
Environmental Fate: Not expected to persist or bioaccumulate, but dilution and treatment of spills is necessary
Mobility: Solid spills stay put unless dispersed by wind or water
Precautions: Avoid entry into water systems, soil drainage; collect and dispose of carefully
Disposal Methods: Gather waste for incineration at licensed hazardous waste facility
Packaging: Use sealed, labeled containers resistant to leaks
Waste Classification: Usually non-RCRA hazardous, check with local, state, national authorities before disposal
Notes: Do not dispose down the sink or in household waste
UN Number: Not regulated for shipping in most regions
Transport Hazard Class: Not classified under UN recommendations
Packing Group: Not assigned
Labels: None required for small research quantities, larger bulk shipments might need labeling under local standards
Shipping Precautions: Prevent movement of container, shield packaging from rough handling and high heat
Other Considerations: Ship with regular chemical goods where not specifically regulated
U.S. Regulations: Not listed by SARA, CERCLA, or TSCA as a hazardous chemical
EU Regulations: Not subject to REACH registration for lab-scale handling
WHMIS (Canada): Not classified as hazardous
Labelling Requirements: Provide information on hazards, safety measures, emergency contacts
Other Policies: Local university or workplace safety guidelines always take priority for lab use
Restrictions: Use PPE, adhere to all workplace chemical handling rules
