Product Name: N-Amino Ethyl Pyrrolidine
Synonyms: 1-(2-Aminoethyl)pyrrolidine
Chemical Family: Amines
CAS Number: 1585-11-1
Recommended Use: Intermediate in chemical synthesis, laboratory reagent
Manufacturer Information: Supplier contact, emergency phone number, and address found on packaging or requisition records
Molecular Formula: C6H14N2
Molecular Weight: 114.19 g/mol
Emergency Overview: Colorless to yellowish liquid, characteristic amine odor, irritating to eyes and respiratory system
Classification: Acute toxicity (oral, dermal, inhalation), skin corrosion/irritation, eye damage/irritation
Label Elements: Danger, corrosive pictogram, exclamation mark pictogram
Hazard Statements: Harmful if swallowed or inhaled, causes severe skin burns and eye damage, may cause respiratory irritation
Precautionary Statements: Avoid breathing mist or vapors, wash hands after handling, use only outdoors or in well-ventilated area, wear protective gloves, eye protection, face shield
Potential Health Effects: Irritation to skin, eyes, and mucous membranes; breathing high concentrations could lead to lung damage
Symptoms of Overexposure: Burning sensation, cough, headache, nausea, vomiting, dizziness, eye redness, blurred vision
Regulatory Listing: Listed as hazardous under OSHA (GHS), WHMIS, EU CLP
Chemical Name: N-Amino Ethyl Pyrrolidine
CAS Number: 1585-11-1
EC Number: 216-437-6
Content: >98% purity
Impurities: Water (<1%), trace secondary amines as remnants from synthesis
Immediate Action: Move affected person away from source and into fresh air
Inhalation: Remove to fresh air, support breathing if needed, seek medical attention immediately
Skin Contact: Remove contaminated clothing rapidly, rinse skin with copious amounts of water for at least 15 minutes, seek medical supervision
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, consult ophthalmologist
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice promptly, never administer anything by mouth to unconscious person
Special Note to Doctor: Treat symptomatically, consider corrosive effects on mucous membranes, airways, and gastrointestinal tract
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Direct water jet
Special Hazards: Emits toxic fumes of nitrogen oxides, carbon monoxide, and carbon dioxide when heated strongly, potential for violent run-off from reaction with water
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear resistant to corrosive chemicals
Methods for Firefighting: Use water spray to cool unopened containers, avoid inhalation of decomposition products
Explosion Risk: Vapors may form explosive mixture with air in confined spaces
Personal Precautions: Evacuate non-essential personnel, ventilate spill area, avoid inhalation and contact with skin or eyes, utilize full PPE
Environmental Precautions: Prevent entry into waterways, drains, soil, or sewers, contain spillage with inert absorbent
Containment and Clean-up: Absorb with sand, earth, or suitable inert material, scoop into secure chemical waste containers, flush area with large amounts of water, ventilate thoroughly
Decontamination: Clean contaminated surfaces with a 10% sodium bicarbonate solution, avoid use of combustible cleaning agents
Disposal of Collected Spill: Dispose in accordance with local, regional, and national environmental regulations
Safe Handling: Use in well-ventilated chemical fume hood, avoid creating aerosols, avoid contact with skin, eyes, and clothing, do not eat, drink, or smoke in work areas, wash thoroughly after handling
Technical Measures: Keep container tightly closed, ground and bond containers for transfer, use explosion-proof equipment if necessary
Storage Conditions: Store in a cool, dry, well-ventilated area away from incompatible substances such as acids, oxidizers, halogens, and chlorinated compounds
Container Materials: Use only corrosion-resistant, tightly sealed containers clearly labeled
Storage Temperature: Ambient temperature (15–25°C) recommended, do not store above 40°C
Storage/Segregation: Separate from foodstuffs, incompatible chemicals, reducing agents
Exposure Limits: No OSHA or ACGIH exposure limit established; minimize exposure using good industrial hygiene
Engineering Controls: General exhaust and local ventilation, chemical fume hood preferred
Respiratory Protection: NIOSH/MSHA-approved organic vapor respirator or powered air-purifying respirator in absence of ventilation
Skin Protection: Chemical-resistant gloves (butyl rubber, nitrile), long-sleeved lab coat, coverall, and boots
Eye/Face Protection: Chemical safety goggles and full face shield
Hygiene Measures: Wash hands, face, and exposed skin after handling, do not eat, drink, or touch eyes while working under exposure risk
Appearance: Clear, colorless to slightly yellow liquid
Odor: Amine-like, pungent
Odor Threshold: Not established
pH: Alkaline, typical for amines
Melting Point/Freezing Point: -22°C
Initial Boiling Point & Range: 185–188°C
Flash Point: 70°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable in presence of open flames, ignition sources
Upper/Lower Flammability or Explosive Limits: Lower: 1.2%, Upper: 8.7% (estimated)
Vapor Pressure: 1 mmHg @ 25°C
Vapor Density: 3.9 (Air = 1)
Relative Density: 0.95 @ 20°C
Solubility: Miscible with water, ethanol, organic solvents
Partition coefficient (n-octanol/water): Log Kow: -0.84, indicative of high water solubility
Auto-Ignition Temperature: 290°C
Decomposition Temperature: Above 200°C
Viscosity: 1.2 mPa·s at 25°C
Chemical Stability: Stable under recommended storage and handling conditions, will slowly oxidize in air
Reactivity: Strong base, reacts vigorously with acids, alkylating agents, acyl halides, oxidizers
Hazardous Reactions: Releases heat on contact with acids; may react with halogenated solvents to form toxic compounds
Conditions to Avoid: Heat, flames, sparks, static discharge, moisture ingress
Incompatible Materials: Strong acids, oxidizing agents, halogenated hydrocarbons
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen cyanide under incomplete combustion
Likely Routes of Exposure: Inhalation, skin, eyes, ingestion
Acute Toxicity: Oral LD50 (rat): ~350 mg/kg; Dermal LD50 (rabbit): ~780 mg/kg; Inhalation LC50 data not available
Skin Corrosion/Irritation: Strongly corrosive, causes severe burns
Serious Eye Damage/Irritation: Produces burns, potential for permanent eye damage
Respiratory Sensitization: Not established, but may cause airway irritation
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Mutagenicity: No data available for mutagenic effects
Reproductive Toxicity: No reproductive toxicity data; handle with care in all reproductive age populations
Repeated Dose Toxicity: Data not available, prolonged exposure likely to damage mucous membranes, skin, respiratory system
Ecotoxicity: Harmful to aquatic organisms, significant risk of environmental damage due to high water solubility
Persistence and Degradability: Moderately biodegradable, yet may persist under some conditions
Bioaccumulative Potential: Low, log Kow value indicates compound does not bioaccumulate
Mobility in Soil: High, readily moves through soil and can contaminate groundwater
Environmental Precautions: Avoid release to environment, treat spills and rinsate as chemical waste
Other Adverse Effects: Data limited, expected to cause alkaline pH disturbances in water bodies
Waste Treatment Methods: Collect residual material for licensed chemical disposal, must not be disposed of with household garbage or via public sewage
Disposal of Contaminated Packaging: Empty container retains product residue, dispose as hazardous waste following triple-rinse, comply with local, state, and federal regulations
Special Disposal Methods: Neutralization with weak acids under controlled conditions, followed by professional chemical waste management
Environmental Hazards: Do not allow to enter water bodies, soil, or drains
Regulatory Requirements: Must adhere to waste code for amines and hazardous organic bases
UN Number: 2734
Proper Shipping Name: Amines, liquid, corrosive, n.o.s. (contains N-Amino Ethyl Pyrrolidine)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Marine Pollutant: Not marine pollutant per IMDG
Environmental Hazards: Yes
Special Precautions for Transport: Shipping containers secure and upright, secondary containment advised, emergency response guide code 153
Labeling Requirement: Corrosive, UN2734
OSHA Status: Regulated hazardous chemical
TSCA Inventory: Listed
SARA Title III: Section 311/312 (acute, chronic hazards); not reportable Section 313
EPCRA: Not a reportable chemical under EPA chemicals of concern
DSL/NDSL: Present on Canadian DSL
REACH Status: Registration may be required in EU above certain quantities
WHMIS Classification: D1B (Toxic), E (Corrosive), D2B (Irritant)
RCRA: Classified as hazardous waste
International Inventories: Listed on AICS (Australia), ENCS (Japan), IECs (Korea), PICCS (Philippines), NZIoC (New Zealand)
Labelling According to GHS: Signal word Danger, contains N-Amino Ethyl Pyrrolidine, hazard pictograms, hazard and precautionary statements as required
