Product Name: N-(2-Hydroxyethyl)-Piperidine
Chemical Formula: C7H15NO
Synonyms: 2-(Piperidin-1-yl)ethanol
CAS Number: 143-19-1
Recommended Use: Laboratory chemicals, chemical intermediates
Supplier Details: Manufacturer, distributor or importer address, business telephone, emergency response contact
Intended Use: For research, industrial, or synthesis applications in organic chemistry labs and production facilities
Email Contact: Dedicated email for safety and compliance queries at the supplier or responsible party
GHS Classification: Serious eye damage/eye irritation (Category 2A), skin irritation (Category 2), acute toxicity (Category 4, oral)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation. Harmful if swallowed. May cause respiratory irritation if vapor or mist forms.
Pictograms: Exclamation mark for general hazard, corrosion for eye and skin
Precautionary Statements: Wash hands and exposed skin thoroughly after handling. Avoid breathing dust, mist, or vapor. Wear protective gloves, clothing, and eye protection. Get medical attention if you feel unwell or develop symptoms. Store in well-ventilated place, keep container tightly closed.
Chemical Name: N-(2-Hydroxyethyl)-Piperidine
Concentration: 98–100% by weight unless diluted for use
Impurities: Trace amounts of related piperidine or ethanolamines, water less than 2%
CAS Number: 143-19-1
EC Number: 205-585-6
Molecular Weight: 129.2 g/mol
Hazardous Components: Main ingredient covers primary hazards due to its irritant and harmful properties
Stabilizers or Additives: None intentionally added for most laboratory and production batches
Eye Contact: Flush eyes gently with clean water for at least 15 minutes while holding eyelids apart, remove contact lenses if worn, continue rinsing, seek immediate medical advice if irritation persists
Skin Contact: Remove contaminated clothing, wash exposed areas thoroughly with soap and water, seek medical attention if irritation develops or persists
Inhalation: Move person to fresh air, keep comfortable for breathing, get medical attention if symptoms occur or respiratory distress develops
Ingestion: Rinse mouth with water, do not induce vomiting, seek prompt medical attention, never give anything by mouth to an unconscious person
Notes for Physicians: Symptomatic treatment only, monitor airway and respiration, treat irritation and exposure as per individual presented symptoms
Suitable Extinguishing Media: Carbon dioxide, foam, water spray, dry chemical
Hazards from Combustion: Produces irritating or toxic fumes including nitrogen oxides, carbon monoxide, carbon dioxide
Protective Equipment and Precautions: Firefighters wear self-contained breathing apparatus and full protective gear to prevent contact with skin and eyes, avoid breathing combustion products
Advice for Responders: Evacuate area, fight fire from upwind, prevent runoff to water drains or open water
Special Fire Risk: Vapors might form explosive mixture with air in confined and heated conditions
Personal Precautions: Use personal protective equipment, avoid breathing vapor, dust or mist, evacuate unprotected personnel from spill area, provide adequate ventilation
Environmental Precautions: Prevent spill from reaching drains, surface water, or soil, alert authorities in case of any large release
Cleanup Methods: Absorb spilled material with inert, non-combustible absorbent (sand, earth, vermiculite), thoroughly clean spill area, place material in correctly labeled disposal container, ventilate region after cleanup
Other Instructions: Prevent skin and eye contact during all stages of spill response
Handling Precautions: Always use in well-ventilated area, avoid inhalation, ingestion, and contact with skin, eyes, and clothing, do not eat, drink, or smoke around chemical, wash hands before breaks and after handling, use smallest quantities possible
Storage Conditions: Store sealed in original container in cool, dry, and well-ventilated place, keep away from incompatible materials such as strong oxidizing agents and acids, maintain temperature below 25°C where feasible, protect from direct sunlight, moisture, and ignition sources
Engineering Controls: Use under fume hood in laboratory, establish spill containment area for larger-scale storage
Exposure Limits: No specific occupational exposure limits set; minimize exposure as with any irritant or harmful chemical
Engineering Controls: Use chemical fume hood or local exhaust for vapor control, maintain adequate general room ventilation, have eye wash station and safety shower readily accessible
Personal Protective Equipment: Nitrile or neoprene chemical-resistant gloves, lab coat or overalls, safety goggles or face shield for splash protection, respiratory protection if airborne concentrations exceed safe limits; use NIOSH/MSHA-approved respirators where needed
Hygiene Measures: Change contaminated clothing promptly, clean hands and face thoroughly after handling
Appearance: Colorless liquid or semisolid, hygroscopic, mild amine-like odor
Boiling Point: 196–200°C at standard atmospheric pressure
Melting Point: -15°C
Solubility: Soluble in water, alcohols, most polar organic solvents
Density: 0.996–1.01 g/cm³ at 20°C
Vapor Pressure: 0.09 mmHg at 20°C
Viscosity: Low, flows easily at room temperature
pH (aqueous): 11–12 (in dilute solution)
Flash Point: 80–90°C (closed cup)
Odor Threshold: Not determined with precision
Partition Coefficient (log Kow): -0.52
Autoignition Temperature: 325°C
Chemical Stability: Stable under normal conditions if stored in sealed container, degradation may occur with prolonged exposure to air, heat, or light
Reactivity: Mildly alkaline, reacts with acids, acid chlorides, and some oxidizers forming hazardous byproducts
Conditions to Avoid: Heat sources, direct sunlight, open flames, strong oxidizing agents, humidity
Hazardous Decomposition Products: Nitrogen oxides, carbon oxides, amines, other toxic organic vapors
Incompatible Materials: Strong acids, acid chlorides, oxidizing agents, copper and copper alloys
Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: Oral LD50 (rat): 1000–1800 mg/kg. Harmful by ingestion, causes moderate irritation to mucous membranes. Dermal and inhalation toxicity lower but possible with high levels
Corrosiveness/Irritation: Skin and eye irritant, can cause redness, pain, and swelling; inhalation may irritate respiratory tract
Chronic Health Effects: Prolonged exposure can dry or crack skin; possible sensitization or allergic reactions rare, no evidence of carcinogenicity or reproductive toxicity from available sources
Symptoms of Overexposure: Headache, nausea, dizziness, coughing, irritated eyes and skin
Ecotoxicity: Expected to be toxic to aquatic organisms in high concentrations, significant dilutions potentially lower risk
Mobility: Readily disperses in aqueous environments, potential for leaching into groundwater after large release
Persistence and Degradability: Moderately biodegradable by standard environmental microorganisms but can persist in low-oxygen conditions
Bioaccumulative Potential: Low; log Kow indicates limited accumulation in aquatic food chains
Other Adverse Effects: Localized harm to soil microfauna possible with repeated or high-level exposure; chemical spills should be remediated to prevent environmental loading
Waste Treatment Methods: Dispose of small amounts by qualified chemical waste incineration with flue gas scrubbing, follow regional, national, and international waste regulations
Container Disposal: Empty containers should be triple-rinsed, punctured, and sent to approved waste facility, do not reuse
Precautions: Do not drain to environment or landfill, ensure waste remains in compatible and labeled container until disposal, contaminated materials treated as hazardous waste
UN Number: Not specifically assigned for small quantities, transport in compliance with local guidelines for organic amines
ADR/RID/IMDG/IATA: Not listed as dangerous good in most international transport systems at typical concentrations
Packing Group: None unless part of large volumes or scheduled shipment
Transport Hazards: Avoid external contamination, keep away from incompatible chemicals during transit, secure packaging to avoid leaks or impacts
Proper Shipping Name: Refer to local and international guidance for naming rules, default to "Chemical, N.O.S." if not exempt
United States: Not specifically regulated under TSCA, RCRA, CERCLA, SARA Title III; subject to OSHA Hazard Communication Standard as hazardous material
EU: Subject to REACH regulations, safety data sheet required, classified as irritant under CLP Regulation
Canada: Listed on DSL, WHMIS requirements apply, classified as eye/skin irritant
Asia-Pacific: Referenced under inventories for Japan (ENCS), China (IECSC), Australia (AICS), and Korea (KECI)
Safety Labeling: Standard hazard and precautionary pictograms and statements as outlined by GHS, displayed on all primary and secondary containers in workplace settings
Other Requirements: Labelling, transport, and storage responsibility falls on chemical users, ongoing safety review for new research and regulatory updates
