Product Name: Methylpyrrolidine
Chemical Formula: C5H11N
CAS Number: 120-94-5
Recommended Uses: Intermediate for organic synthesis, solvent in labs, chemical research applications
Supplier Information: Company Name, Emergency Contact Number, Address, Email
Hazard Classification: Flammable liquid (Category 3), Acute Toxicity (Category 4, oral and inhalation), Skin Irritation (Category 2), Eye Irritation (Category 2A)
GHS Label Elements: Flame, Exclamation Mark
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed, inhaled, or absorbed through skin. Causes skin and serious eye irritation.
Precautionary Statements: Keep away from heat, sparks, open flames. Wear protective gear. Use only outdoors or in well-ventilated area.
Chemical Name: N-Methylpyrrolidine
Concentration: 98–100%
Synonyms: 1-Methylpyrrolidine
Impurities: Water (<1%), residual solvents (<0.5%)
Inhalation: Move person to fresh air. Monitor breathing, seek medical help if symptoms show up. Avoid further exposure by ensuring clean air.
Skin Contact: Rinse skin with plenty of water. Remove contaminated clothing and wash thoroughly. Get medical attention for persistent irritation.
Eye Contact: Rinse immediately with running water, holding eyelids open. Remove contact lenses if present and easy. Go to doctor if irritation persists.
Ingestion: Rinse mouth, avoid inducing vomiting. Give plenty of water if person is alert. Provide medical attention as soon as possible.
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Water jet
Special Hazards: Vapors can form explosive mixture with air, keep away from all ignition sources. Burning gives off toxic fumes including nitrogen oxides.
Protective Equipment For Firefighters: Full protective suit, self-contained breathing apparatus
Hazardous Decomposition: Carbon monoxide, carbon dioxide, nitrogen oxides
Personal Precautions: Evacuate unnecessary personnel, ventilate area, avoid breathing vapors.
Protective Equipment: Chemical-resistant gloves, goggles, and protective clothing
Environmental Precautions: Stop leakage if safe, prevent entry into drains, sewers, and waterways.
Clean Up Methods: Absorb with inert, non-combustible material like sand or earth. Scoop up and place in chemical waste container. Ventilate area and wash spill site after material pickup complete.
Handling Precautions: Use in a well-ventilated area, avoid inhaling vapors and contact with skin or eyes. Use spark-proof tools. Ground containers and equipment during transfer.
Storage Conditions: Store in tightly-sealed container, in cool, dry, well-ventilated space. Keep away from open flames, heat, and incompatible substances like oxidizing agents or strong acids. Avoid exposure to sunlight or temperature extremes.
Control Parameters: No established occupational exposure limits. Use local exhaust or general room ventilation.
Personal Protective Equipment: Chemical splash goggles, gloves resistant to organic solvents (nitrile recommended), lab coat, and protective footwear. In case of insufficient ventilation, wear air-purifying respirator with organic vapor cartridge.
Hygiene Measures: Wash hands after handling, remove contaminated clothing, avoid eating, drinking, or smoking in work area.
Appearance: Colorless to pale yellow liquid
Odor: Amine-like, fishy
pH: Alkaline
Melting Point: -59 °C
Boiling Point: 90–92 °C
Flash Point: 18 °C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable
Vapor Pressure: 27 mmHg at 25 °C
Solubility: Miscible in water and most organic solvents
Density: Approx. 0.87 g/cm³ (at 20 °C)
Viscosity: Not determined
Chemical Stability: Stable at room temperature under recommended storage conditions
Reactivity: Reacts with strong oxidizers, acids, and acid chlorides
Conditions To Avoid: Heat, open flames, static electricity, sunlight
Hazardous Decomposition: Emits toxic fumes under fire conditions – carbon oxides, nitrogen oxides
Polymerization: No hazardous polymerization observed
Possible Routes Of Exposure: Inhalation, skin absorption, ingestion, eye contact
Symptoms: Respiratory tract irritation, dizziness, headaches, skin redness, eye redness and watering, nausea
Acute Toxicity: Oral LD50 (rat): ~350 mg/kg. Inhalation LC50 (rat): data not fully available. Skin: may cause moderate irritation.
Long-term Effects: No specific chronic toxicity identified, but prolonged contact may defat skin or sensitize lungs
Carcinogenicity / Mutagenicity: No data indicating cancer risk from methylpyrrolidine exposure
Ecotoxicity: Harmful to aquatic life, high solubility increases mobility in water
Persistence and Degradability: Expected to be biodegradable, but may persist in water if spill volume is large
Bioaccumulation: Low potential for bioaccumulation
Mobility in Soil: High, due to miscibility with water
Other Adverse Effects: Avoid uncontrolled discharge into the environment, risk of water contamination
Waste Disposal Methods: Collect in closed and labeled chemical waste containers. Dispose through licensed hazardous waste contractor.
Contaminated Packaging: Rinse container, then destroy by controlled incineration or dispose as hazardous waste.
Environmental Precautions: Do not discharge waste into sewers, waterways, or soil.
UN Number: UN 2733
Proper Shipping Name: Methylpyrrolidine
Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels Required: Flammable liquid
Special Precautions: Protect from physical damage, keep away from ignition sources during transport. Follow local, national, and international regulations for hazardous chemicals.
U.S. Regulations: TSCA listed, SARA Title III Section 311/312 (immediate health hazard, fire hazard)
EU Regulations: EC 1272/2008 (CLP), not listed under REACH Annex XIV or XVII restrictions
Other Country Inventories: Listed on major chemical inventories (Canada DSL, Australia AICS, Japan ENCS, Korea ECL)
Labeling Requirements: Flammable, harmful, irritant as per GHS/CLP
Restrictions: Regulatory details vary by country, consult local authorities for guidance on use and disposal.
