Product Name: Methyl 3-Amino-4-Methyl-2-Thenoate
Chemical Formula: C7H9NO2S
Chemical Family: Thienoate Derivative
CAS Number: 98613-27-9
Synonyms: 3-Amino-4-methyl-2-thiophenecarboxylic acid methyl ester
Product Use: Intermediate in organic synthesis and pharmaceuticals
Manufacturer: [Company Name], [Address], [Phone], [Email]
Emergency Contact: [Emergency Contact Number, 24-Hour Hotline]
GHS Classification: Acute Toxicity (Oral) Category 4, Eye Irritant Category 2A, Skin Irritant Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Pictograms: Exclamation mark
Precautionary Statements: Avoid inhalation, ingestion, and skin and eye contact. Use only outdoors or in well-ventilated area. Wear protective gloves, protective clothing, and eye/face protection.
Potential Health Effects: May cause irritation to eyes, skin, and respiratory tract. Ingestion may result in stomach discomfort or other harmful effects. Prolonged exposure may worsen health effects.
Other Risks: Dust or vapors may cause allergy-like symptoms in sensitized individuals. Environmental hazard if released in significant quantities.
Chemical Name: Methyl 3-Amino-4-Methyl-2-Thenoate
Common Name: None
CAS Number: 98613-27-9
Concentration: > 98% (by weight)
Impurities: Trace organic solvents (< 2%)
Additives: None reported in standard grade material
Physical State: Solid (crystalline powder)
General: Seek medical attention if feeling unwell or if irritation persists after exposure. Move person to fresh air.
Inhalation: Remove individual to an area with fresh air. Keep at rest. Monitor for respiratory distress. If symptoms continue, seek medical aid.
Skin Contact: Immediately remove any contaminated clothing. Wash exposed skin thoroughly with soap and water for several minutes. Monitor for rash or irritation.
Eye Contact: Rinse with water for several minutes, holding eyelids open. Remove contacts if possible. Continue flushing with water; get medical help right away.
Ingestion: Rinse mouth, do not induce vomiting unless instructed by medical professionals. Drink water if conscious. Get medical assistance promptly.
Most Important Symptoms: Irritation, redness, possible nausea or headache.
Notes for Physicians: Treat symptomatically; monitor for delayed effects on skin and respiratory tract.
Suitable Extinguishing Media: Carbon dioxide, dry chemical, water spray or alcohol-resistant foam
Unsuitable Media: Straight water streams may promote spreading
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, sulfur oxides, nitrogen oxides, possible toxic and irritating fumes
Protective Equipment for Firefighters: Wear full turn-out gear including self-contained breathing apparatus (SCBA). Stay upwind from fire.
Special Procedures: Approach fire from upwind to avoid hazardous vapors, dike runoff water to prevent contamination.
Explosion Sensitivity: No known explosive properties under normal conditions
Personal Precautions: Evacuate spill area for non-essential personnel. Ventilate area well. Use personal protective equipment including gloves and goggles.
Containment Procedures: Prevent further leakage or spillage if safe to do so. Avoid contamination of soil, drains, waterways.
Clean-up Methods: Scoop up spilled material using non-sparking tools and place in suitable containment for disposal. Avoid raising dust. Wash spill site with water after material pickup.
Environmental Precautions: Keep material out of surface water, storm drains, or soil. Notify authorities if large quantities enter public waterways.
Disposal of Spilled Material: Collect in accordance with local, regional, and national regulations.
Handling Precautions: Avoid generating dust. Use in well-ventilated areas. Do not eat, drink, or smoke when handling. Wear gloves, protective clothing, and eye protection. Wash hands and exposed areas with soap and water after use.
Storage Requirements: Store in a tightly sealed container in a dry, cool, well-ventilated place. Keep away from direct sunlight, sources of ignition, and incompatible substances. Do not store with strong oxidizers or acids.
Special Storage Requirements: Ensure containers are labeled and kept upright to prevent spills or leakage.
Exposure Limits: No established exposure limits for this compound, but general dust and irritant control standards apply (e.g., OSHA PEL for particulates: 15 mg/m³ total dust)
Engineering Controls: Use local exhaust ventilation or work in a chemical fume hood. Safety showers and eye wash stations should be available.
Personal Protective Equipment: Chemical-resistant gloves (e.g., nitrile), safety goggles or face shield, lab coat or chemical apron. Respiratory protection recommended if dust or fumes form. Avoid skin contact; use barrier cream if needed.
Hygiene Measures: Do not eat, drink, or smoke in work area. Wash hands and face thoroughly after handling.
Appearance: Off-white to yellowish crystalline powder
Odor: Slight, faintly aromatic or sulfurous
Odor Threshold: Not established
pH: Not available (not soluble in water)
Melting Point: 105 - 111°C
Boiling Point: Not determined; compound may decompose before boiling
Flash Point: > 150°C (estimated)
Evaporation Rate: Not applicable (solid at room temperature)
Flammability: Not highly flammable; capable of burning under strong heat
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: 1.24 g/cm³ (estimated)
Solubility: Slightly soluble in ethanol, methanol, and DMSO; practically insoluble in water
Partition Coefficient (log Kow): Estimated, not available
Auto-ignition Temperature: Not determined
Decomposition Temperature: May decompose above 200°C
Viscosity: Not applicable (solid)
Molecular Weight: 171.22 g/mol
Chemical Stability: Stable under normal temperatures and pressures; avoid prolonged exposure to light and moisture.
Reactivity: Not expected to be reactive under standard conditions.
Conditions to Avoid: Excessive heat, open flames, sources of ignition, prolonged exposure to moisture.
Incompatible Materials: Strong oxidizers, strong bases, strong acids.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, sulfur oxides, and oxides of nitrogen on combustion or decomposition.
Polymerization: Will not occur under standard handling conditions.
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Harmful if swallowed based on similar compounds (estimated LD50 oral, rat: 500 - 2000 mg/kg)
Skin Corrosion/Irritation: May cause moderate irritation on direct or prolonged contact.
Serious Eye Damage/Irritation: Causes eye irritation and may cause redness.
Respiratory Sensitization: May cause irritation if inhaled as dust; sensitization not well documented.
Skin Sensitization: No reliable evidence for skin sensitization, but repeated contact may aggravate dermatitis.
Chronic Toxicity: Not well studied for this specific compound; general concern for target organ effects if chronically exposed.
Mutagenicity: Not tested; thienoate derivatives do not present obvious genotoxic risk based on available literature.
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA.
Reproductive Toxicity: Data not available.
Symptoms of Exposure: Eye, skin, or respiratory tract irritation; nausea, headache, or drowsiness if large amounts are ingested.
Ecotoxicity: Not widely studied, but structurally similar compounds present low to moderate toxicity to aquatic organisms (estimated EC50 for daphnia > 1 mg/L)
Persistence and Degradability: May be persistent under typical environmental conditions; slow microbial degradation expected.
Bioaccumulation Potential: Low to moderate bioaccumulation expected based on solubility and structure.
Mobility in Soil: Limited mobility; likely to adsorb to soil and sediment due to low water solubility.
Other Adverse Effects: Avoid large-scale release into watercourses; unknown long-term effects on terrestrial and aquatic systems.
Waste Disposal Methods: Collect solid waste and contaminated materials in labeled containers. Dispose of by incineration in approved facilities, or under local, state, and federal regulations for hazardous waste.
Container Disposal: Triple-rinse empty containers, then offer for recycling or dispose in accordance with institutional and regulatory requirements.
Precautions: Prevent release into the environment. Avoid disposal in landfill when incineration is available.
Hazardous Waste: Chemical waste classified as hazardous; treat as possible toxic organic compound.
UN Number: Not regulated for transportation by air, sea, or road under standard conditions
UN Proper Shipping Name: Not classified
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant or dangerous good
Special Precautions: Prevent container damage during transport; avoid exposure to moisture or open flame
Transport Labels Required: None for small laboratory quantities; consult with authorities for bulk shipments
OSHA Status: Not specifically regulated as hazardous, yet subject to general chemical safety requirements
TSCA (Toxic Substances Control Act): Listed or anticipated to be listed
SARA 302/304/311/312/313: Not found on SARA regulatory lists
California Proposition 65: Not listed
REACH Status (EU): Pre-registered or registered for intended uses
WHMIS Classification (Canada): Not classified; precautionary guidance applies
National/Local Regulations: Follow standard chemical handling rules; site-specific permit may be required for storage or disposal
Other Standards: Users should consult national, state, and local authorities for comprehensive compliance.
