Substance name: Α-Methyl-1H-Imidazole-1-Ethanol
Chemical formula: C6H10N2O
SYNONYMS: 1-(1H-Imidazol-1-yl)-2-propanol, α-Methylimidazoleethanol
UN Number: Not assigned
Recommended Uses: Intermediate for pharma synthesis, laboratory chemical, specialty solvent
Manufacturer / Supplier: [Your Company Name], [Your Company Address], [Contact Number], [Emergency Contact]
CAS Number: 23018-05-1
Email for SDS: [Email Address]
Classification (GHS): Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity oral (Category 4)
Label Elements: Warning, Exclamation mark pictogram
Hazard Statements: Causes skin irritation. Causes serious eye irritation. Harmful if swallowed.
Precautionary Statements: Avoid contact with eyes, skin, and clothing. Do not eat, drink or smoke when using product. Wear protective gloves, eye and face protection.
Signal Word: Warning
Routes of entry: Inhalation, ingestion, skin and eye contact
Potential Health Effects: Burning sensation on skin, temporary blurred vision, cough if inhaled
Target Organs: Eyes, skin, gastrointestinal tract
Chronic Health Hazards: Repeated exposure may lead to skin dryness or cracking
Chemical Name: Α-Methyl-1H-Imidazole-1-Ethanol
Common Name: 1-(1H-Imidazol-1-yl)-2-propanol
CAS Number: 23018-05-1
EC Number: Not assigned
Impurities or Stabilizing Additives: No significant impurities above disclosure limits
General Advice: Take victim to fresh air. Separate from exposure sources. Remove contaminated clothing.
If Inhaled: Move person to fresh air. Give artificial respiration if breathing has stopped. Seek medical attention.
If on Skin: Wash with plenty of soap and water for at least 15 minutes. If irritation persists, seek medical advice.
If in Eyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. If irritation does not subside, consult an ophthalmologist.
If Swallowed: Rinse mouth with water, do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. Obtain medical attention.
Suitable Extinguishing Media: Water spray, dry chemical, alcohol-resistant foam, carbon dioxide
Specific Hazards Arising: Combustion may yield toxic vapors, including nitrogen oxides, carbon monoxide and carbon dioxide
Advice for Firefighters: Wear self-contained breathing apparatus, chemical protective clothing
Protective Equipment: Full protective suit, gloves, eye protection
Further Information: Prevent fire-extinguishing water from entering drains or watercourses, as contamination risk rises. Containers may explode under fire conditions.
Personal Precautions: Avoid breathing vapors, provide adequate ventilation, evacuate personnel from affected area, avoid skin and eye contact. Wear chemical-resistant gloves, goggles, face shield.
Environmental Precautions: Prevent further leakage or spillage if safe to do. Prevent product from entering drains, sewers, or water bodies.
Cleanup Methods: Absorb with inert material such as dry sand, earth, or a commercial absorbent. Sweep and shovel into suitable containers. Ventilate area and wash spill site with copious amounts of water after material pickup is complete.
Disposal: Dispose of contaminated materials as hazardous waste following local regulations.
Handling: Use only in a well-ventilated area. Avoid vapor formation and contact with eyes, skin, and clothing. Practice good hygiene—wash hands after handling, remove contaminated clothing, do not eat or drink during use.
Storage: Keep tightly closed in original container. Store in a cool, dry, well-ventilated location, away from heat sources and incompatible substances such as oxidizers and acids. Protect from sunlight and moisture.
Safe Storage Temperature: 2-8°C
Incompatible Materials: Strong oxidizers, strong acids
Recommended Containers: Shatter-resistant, chemically compatible, clearly labeled
Occupational Exposure Limits: No specific exposure limit established for this compound
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits
Personal Protective Equipment:
- Eye Protection: Safety glasses with side-shields or full-face shield
- Hand Protection: Chemical-resistant gloves (nitrile or neoprene)
- Skin Protection: Long-sleeved laboratory coat or chemical-resistant apron
- Respiratory Protection: In circumstances where risk assessment shows air-purifying respirators are appropriate, use an approved respirator with organic vapor cartridge, especially during handling of large quantities or potential for aerosol formation
- Hygiene Practices: Wash hands before breaks and at end of workday, do not wear contaminated clothing outside workspace
Appearance: Clear to pale yellow liquid
Odor: Mild amine-like
pH: Approximately 8 (1% solution in water)
Melting/Freezing Point: - Not determined (liquid at room temperature)
Boiling Point: Approx. 280°C
Flash Point: 110°C (Closed Cup)
Evaporation Rate: Not determined
Flammability: May form combustible mixtures at elevated temperature
Vapor Pressure: Low at ambient conditions
Relative Density: ~1.09 (water=1)
Solubility: Miscible with water
Partition coefficient (n-octanol/water): Not determined
Viscosity: Not determined
Explosive Properties: No data available
Oxidizing Properties: None
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Avoid contact with strong oxidizing agents and acids
Hazardous Reactions: Can react vigorously with oxidizers and incompatible chemicals
Decomposition Products: Toxic fumes of carbon oxides and nitrogen oxides possible upon thermal decomposition
Conditions to Avoid: Heat, flames, sparks, high temperatures, exposure to air or moisture for prolonged periods
Polymerization: Not expected under normal handling
Acute Toxicity: LD50 (oral, rat): ~300 mg/kg (estimated)
Skin Corrosion/Irritation: Causes irritation with redness
Eye Damage/Irritation: Causes serious irritation, watering, and transient blurred vision
Respiratory or Skin Sensitization: Not classified as a sensitizer
Germ Cell Mutagenicity: Not tested
Carcinogenicity: No data available, not classified by IARC, NTP, or OSHA
Reproductive Toxicity: No data available
Specific Target Organ Toxicity (Single Exposure): May cause drowsiness, dizziness at high levels
Specific Target Organ Toxicity (Repeated Exposure): Not classified
Aspiration Hazard: Not considered an aspiration hazard
Potential Health Symptoms: Headache, nausea, skin and eye burning, coughing
Medical Conditions Aggravated by Exposure: Pre-existing skin, respiratory, or eye disorders
Toxicity to Aquatic Life: Not expected to pose significant acute hazard in small quantities, but large spills may affect aquatic organisms
Persistence and Degradability: Biodegradability not fully determined; likely to undergo slow degradation in soil and water
Bioaccumulation Potential: Low potential due to high solubility
Mobility in Soil: Likely to be mobile in wet environments
Other Adverse Effects: Precaution advised due to imidazole ring structure potentially affecting biological systems in water
Precautions for Environment: Prevent release in surface water, ground water, or soil
Disposal Methods: Collect and place in leak-proof, labeled containers for proper disposal through licensed facility
Unused Product: Treat as hazardous waste; incinerate in chemical incinerator equipped with afterburner and scrubber; do not dispose via sinks or drains
Contaminated Packaging: Empty containers retain product residue; treat as hazardous; offer for recycling if possible, or incinerate
Disposal Regulations: Dispose in accordance with local, regional, and national regulations
UN Number: Not regulated
Transport Hazard Class: Not classified as dangerous for transportation
Packing Group: Not assigned
Marine Pollutant: Not classified
Special Precautions: Keep tightly sealed, upright, and in secondary containment for transit
Proper Shipping Name: Α-Methyl-1H-Imidazole-1-Ethanol (chemical, non-hazardous)
Transport in Bulk (Annex II MARPOL 73/78): Not listed
Transport Labels Required: None under current standards
OSHA Status: Not regulated as hazardous
TSCA: Listed
SARA Title III Sections 302, 304, 311/312, 313: Not listed
DSL/NDSL (Canada): Not listed
California Proposition 65: Not listed
Other National Inventories: Check local chemical inventory
Labeling Requirements: Ensure label includes product name, hazard pictograms, precautionary and hazard statements, contact information for responsible party
Workplace Restrictions: Use only for intended applications in accordance with local, regional, and national health and safety regulations
