Product Name: Homopiperazine
Chemical Formula: C5H12N2
CAS Number: 505-66-8
Recommended Use: Chemical synthesis, intermediate, research
Manufacturer or Supplier: Chemical supply companies, research distributors
Contact Information: Address and emergency phone numbers listed directly by supplier
Email Address: Provided by supplier on packaging or order details
Emergency Overview: White to off-white crystalline powder, slight ammonia odor, harmful if swallowed, causes skin and eye irritation
GHS Classification: Acute Toxicity Oral Category 4, Eye Irritation Category 2A, Skin Irritation Category 2
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves/protective clothing/eye protection/face protection, do not eat, drink, or smoke when using this product
Symptoms: Burning sensation, sneezing, coughing, redness, pain in eyes, nausea if ingested
NFPA Ratings: Health: 2, Flammability: 1, Instability: 0
Chemical Identity: Homopiperazine
Chemical Formula: C5H12N2
EC Number: 208-008-7
Concentration: 97%–100% (pure compound)
Impurities: Traces of related cyclic amines, possibly residual solvents from synthesis, below safety thresholds for major suppliers
Eye Contact: Immediately flush with plenty of water for at least 15 minutes, remove contact lenses, seek medical attention if irritation persists
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, seek medical help if redness or irritation develops
Inhalation: Move to fresh air, keep at rest, administer artificial respiration if breathing stops, contact a physician
Ingestion: Rinse mouth with water, do not induce vomiting, call poison control or a physician immediately
Acute Symptoms: Irritation, coughing, nausea, burning sensation in throat or stomach, dizziness
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Media: Strong water jet may spread material
Hazardous Combustion Products: Nitrogen oxides, carbon oxides, ammonia fumes
Specific Hazards: Dust may form explosive mixture with air, toxic vapors possible under fire conditions
Protective Equipment: Wear self-contained breathing apparatus and full protective gear to avoid inhalation of vapors
Firefighting Instructions: Avoid breathing dust or fumes, keep containers cool with water spray, evacuate area if necessary
Personal Precautions: Evacuate unnecessary personnel, use personal protective equipment including, gloves, goggles, protective clothing
Environmental Precautions: Keep material out of drains, surface or groundwater, report spillage to proper environmental authorities if required
Methods for Cleanup: Sweep or scoop up material without creating dust, place in tightly closed container for disposal, clean spill area with soap and water, ventilate area
Prevention of Secondary Hazards: Remove ignition sources, avoid dust buildup, use tools that won’t spark
Safe Handling: Avoid contact with skin and eyes, work in well-ventilated area or fume hood, do not breathe dust, keep away from heat, open flame, sparks
Hygiene Practices: Wash hands after handling, remove contaminated clothing and wash before reuse, keep food and drinks away from work area
Storage: Keep in tightly closed original container, store in a cool, dry, well-ventilated location out of direct sunlight, segregate from oxidizers, acids or strong bases, keep away from incompatible materials
Storage Temperature: Recommended below 25°C, avoid freezing or excessive heat
Exposure Limits: No formal occupational exposure limits published, handle with care using standard controls
Engineering Controls: Laboratory fume hood or local exhaust ventilation, eyewash stations, safety showers nearby
Personal Protection: Chemical-resistant gloves (nitrile or neoprene), goggles or face shield, lab coat, closed-toe shoes, NIOSH-approved particulate respirator for dust or aerosols
Environmental Controls: Prevent run-off into water sources, use secondary containment for large quantities
Appearance: White, off-white crystalline solid or powder
Odor: Slightly ammoniacal
Odor Threshold: Not established
pH: Alkaline in water solution
Melting Point: 44°C–48°C
Boiling Point: 272°C at standard pressure
Flash Point: 136°C (closed cup)
Evaporation Rate: Not determined for solid
Flammability: Low, combustible solid
Vapor Pressure: Negligible at room temperature
Vapor Density: Not determined
Relative Density: 0.99–1.01 g/cm³
Solubility in Water: Miscible
Solubility in Other Solvents: Ethanol, acetone, methanol
Partition Coefficient (log Kow): 0.54
Auto-Ignition Temperature: Above 360°C
Decomposition Temperature: Above 200°C
Viscosity: Not applicable to solid form
Chemical Stability: Stable under normal temperatures and pressures
Incompatible Materials: Strong acids, oxidizing agents, acyl chlorides, acid anhydrides
Reactivity: Non-reactive with most materials under controlled conditions
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, ammonia, other toxic vapors under fire
Polymerization: Does not polymerize
Special Conditions: Avoid dust generation, moisture, and prolonged exposure to air
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: LD50 (oral, rat) approximately 669 mg/kg
Skin Irritation: Mild to moderate irritation possible
Eye Irritation: Severe irritation, redness, and pain possible
Inhalation Risks: Respiratory irritation can occur with dust exposure
Sensitization: No reported cases in literature, but possible with repeated handling
Chronic Effects: Data lacking on long-term use, avoid repeated unprotected contact to minimize uncertainty
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No records in major hazard databases, general chemical caution advised
Other Effects: Nausea, vomit, headache upon significant exposure in animal studies
Ecotoxicity: Low aquatic toxicity expected due to lack of bioaccumulation, precise values not well-documented
Aquatic Organisms: Not classified as hazardous for typical small spills, avoid discharge into the environment to prevent unforeseen effects
Persistence & Degradability: Predicted to undergo slow aerobic degradation in soil and water
Bioaccumulation: Low, due to moderate water solubility and low log Kow
Mobility in Soil: High, due to solubility, possible to reach groundwater if not contained
Other Adverse Effects: Not anticipated under responsible laboratory and industrial use
Waste Disposal: Collect solid waste in tightly sealed containers, label appropriately, dispose of as hazardous chemical waste through licensed firm
Contaminated Packaging: Triple rinse before disposal, follow local regulations
Disposal Methods: Incineration preferred for organic amines, obey all environmental and local authority requirements
Precautions: Do not dispose into municipal or surface water systems, avoid landfill dumping except as allowed by local regulation
UN Number: Not regulated as a dangerous good under most international transport codes
Proper Shipping Name: Homopiperazine, solid
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Environmental Hazards: None listed
Special Precautions: Double containment via sealed packaging, keep upright, secure on pallet during transit, away from food and feed
Regulatory References: Compliant with IATA, IMDG, ADR standards for non-dangerous goods as per most current updates
Inventory Listings: Included in TSCA (US), EINECS (EU), DSL (Canada), AICS (Australia)
Labeling Requirements: GHS-compliant signal word and hazard statements
Workplace Controls: Subject to chemical hygiene plans in regulated workplaces, inclusion in local chemical inventories
Restrictions: None designated for consumer products
Reportable Quantities: Not subject to specific federal reporting in the US
Regulatory Codes: None listed under CERCLA, SARA Title III, or California Proposition 65
Other Legislation: Use governed by industry codes of practice for laboratory chemicals, refer to local environmental, health, and safety laws
