Material Safety Data Sheet: Ethyl Piperidine-1-Propionate

Identification

Product Name: Ethyl Piperidine-1-Propionate
Chemical Formula: C10H19NO2
Synonyms: 1-Piperidinepropanoic acid, ethyl ester
CAS Number: 53590-70-8
Recommended Use: Laboratory reagent, intermediate in chemical synthesis
Manufacturer: [Supplier Information]
Emergency Phone Number: [Contact]

Hazard Identification

GHS Classification: Flammable Liquids (Category 3), Acute Toxicity (Oral, Category 4), Skin Irritation (Category 2), Eye Irritation (Category 2A)
Pictograms: Flame, Exclamation Mark
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Keep away from heat, sparks, open flames. Wear protective gloves and eye protection. Wash hands after handling. Do not eat, drink, or smoke when handling. If in eyes: rinse with water for minutes. If swallowed: call poison center.

Composition / Information on Ingredients

Chemical Name: Ethyl Piperidine-1-Propionate
Concentration: >99%
Impurities: Trace level by-products possible from synthesis
Molecular Weight: 185.26 g/mol
EC Number: [Assigned if available]
Other Ingredients: None reported at significant levels

First Aid Measures

General Advice: Seek medical attention for any exposure effects.
Inhalation: Move person to fresh air. Keep at rest. Provide artificial respiration if not breathing. Get medical aid if symptoms persist.
Skin Contact: Remove contaminated clothing. Flush skin with plenty of water for at least 15 minutes. Seek medical advice if irritation develops.
Eye Contact: Rinse eyes cautiously with water for several minutes, holding eyelids open. Remove contact lenses if present and easy. Continue rinsing. Get medical attention.
Ingestion: Do not induce vomiting. Rinse mouth with water. Never give anything by mouth to an unconscious person. Call poison control or a doctor immediately.

Fire-Fighting Measures

Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide, water spray (use water spray for cooling exposed containers only)
Unsuitable Extinguishing Media: Do not use high pressure water jet
Specific Hazards: Vapors can form explosive mixtures with air. Containers may explode in heat of fire. Decomposition releases toxic gases (nitrogen oxides, carbon monoxide, carbon dioxide).
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full body protective clothing. Avoid inhaling fumes.
Fire-Fighting Instructions: Fight fire from safe distance. Prevent entry of spilled material into waterways or sewers.

Accidental Release Measures

Personal Precautions: Evacuate area. Avoid breathing vapors. Wear appropriate PPE including gloves, goggles, and respirator.
Environmental Precautions: Prevent entry into drains, surface water, and soil.
Methods for Cleaning Up: Absorb spill with inert material (sand, diatomite). Use non-sparking tools. Collect in chemical waste containers. Dispose according to local regulations. Ventilate affected area.
Emergency Procedures: Remove sources of ignition. Warn others of chemical hazard.

Handling and Storage

Handling: Avoid contact with skin, eyes, and clothing. Do not breathe vapors. Work in well-ventilated area. Use non-sparking tools. Keep containers tightly closed.
Storage: Store away from sources of ignition in a cool, dry, ventilated area. Keep away from incompatible materials (oxidizing agents, acids). Keep container tightly sealed. Store in approved chemical storage facilities. Segregate from food and drink.

Exposure Controls and Personal Protection

Exposure Limits: No defined occupational exposure limits for this compound. Use exposure limits for structurally related substances as a guideline.
Engineering Controls: Use exhaust ventilation to keep airborne concentrations low. Emergency showers and eyewash stations required.
Personal Protective Equipment: Chemical resistant gloves (nitrile recommended), safety goggles, lab coat, face shield if splash hazard.
Respiratory Protection: Use NIOSH-approved respirator in absence of adequate ventilation or if exposure thresholds are exceeded.
Hygiene Measures: Wash hands thoroughly after use. Do not eat, drink, or smoke while using this chemical.

Physical and Chemical Properties

Appearance: Clear colorless to pale yellow liquid
Odor: Characteristic amine and ester odor
Odor Threshold: Not determined
pH: Not applicable (organic liquid)
Melting Point / Freezing Point: -15°C (estimated)
Boiling Point: 230–240°C
Flash Point: 85°C (closed cup, estimated)
Evaporation Rate: Not available
Flammability: Flammable liquid
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: 0.12 mmHg at 25°C (estimated)
Vapor Density: >1 (Air = 1)
Specific Gravity: 0.96 g/cm³ at 20°C
Solubility: Slightly soluble in water, soluble in organic solvents
Partition Coefficient (n-octanol/water): 1.5 (estimated)
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not observed below 180°C
Viscosity: Low viscosity liquid

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions.
Thermal Decomposition: May decompose at high temperatures to release toxic fumes.
Reactivity: Not chemically reactive under normal handling. Avoid contact with strong oxidizers, acids, bases.
Hazardous Reactions: None expected under ordinary conditions. Reaction with oxidizers may be violent.
Incompatible Materials: Strong acids, strong oxidizing agents
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, possibly other toxic vapors

Toxicological Information

Acute Toxicity (Oral): Estimated LD50 (rat) 750 mg/kg
Acute Toxicity (Dermal): Estimated LD50 (rabbit) >2000 mg/kg
Acute Toxicity (Inhalation): Data not available, but vapors may cause irritation
Skin Corrosion/Irritation: Causes moderate skin irritation on prolonged contact
Eye Damage/Irritation: Causes serious eye irritation
Respiratory Sensitization: Not classified, but inhalation of vapor can produce irritation
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: No data available—structural analogs not found mutagenic
Reproductive Toxicity: No data available
STOT-single and repeated exposure: Data lacking, but high doses may impact nervous system and liver based on related compounds

Ecological Information

Ecotoxicity: Acute toxicity for aquatic organisms not determined. Expected to be moderately toxic based on structure and physical properties.
Persistence and Degradability: Expected to undergo biodegradation under aerobic conditions.
Bioaccumulative Potential: Moderate potential due to partition coefficient.
Mobility in Soil: Moderately mobile, may leach to groundwater if released in large amounts.
Other Adverse Effects: Prevent entry into waterways. Limited data on long-term environmental effects.

Disposal Considerations

Disposal Methods: Dispose of product and contaminated materials as hazardous chemical waste according to local, regional, and federal regulations.
Contaminated Packaging: Empty containers should be rinsed and disposed of as hazardous waste. Do not reuse containers.
Special Precautions: Do not allow to enter drains, soil, or water bodies. Use labeling and documentation required for chemical waste management.

Transport Information

UN Number: UN3272 (Class 3 Flammable Liquid)
UN Proper Shipping Name: Esters, n.o.s. (contains Ethyl Piperidine-1-Propionate)
Transport Hazard Class: 3
Packing Group: III
Marine Pollutant: Not classified as a marine pollutant
Special Transport Precautions: Keep container tightly closed. Handle containers carefully to prevent damage. Store away from heat sources during transport.
Road/Rail/Sea/Air: Regulated for all major transport modes. Comply with all applicable national and international regulations.

Regulatory Information

TSCA (US): Listed or meets requirements for research and development exemptions
EINECS (EU): Check registration status.
OSHA (US): Classified as hazardous based on criteria for flammable liquids and irritants.
SARA Title III (Sections 311/312): Immediate health, fire hazard
REACH (EU): Subject to registration. Verify compliance.
WHMIS (Canada): Class B2 (Flammable Liquid), D2B (Toxic Material with Other Effects)
Other International Regulations: Subject to country-specific chemical inventories and regulations.
Labeling Requirements: GHS Compliant label with hazard and precautionary statements.