Product Name: Ethyl 4-Oxopiperidine-1-Carboxylate
Chemical Formula: C8H13NO3
Synonyms: 4-Oxopiperidine-1-carboxylic acid ethyl ester
CAS Number: 2721-95-1
Recommended Use: Organic synthesis, pharmaceutical intermediates
Supplier Information: Manufacturer's address, contact phone number, email for safety queries
Emergency Phone: Local poison control center or emergency response number
Relevant Identified Uses: Laboratory chemical, research, not for human or veterinary diagnostic or therapeutic use
GHS Classification: Acute toxicity (oral, inhalation, dermal), skin irritation, eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin irritation, causes serious eye irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust or vapors, wash hands thoroughly after handling, wear protective gloves and eye protection, do not eat, drink, or smoke during use
Potential Health Effects: May cause headaches, nausea, or irritation to eyes and skin upon direct contact or inhalation of dust/fumes
Chemical Name: Ethyl 4-Oxopiperidine-1-Carboxylate
Percentage: 97-100%
Impurities/Additives: Trace residuals from synthesis process, including possible solvents used in manufacturing (typically below 0.5%)
Molecular Weight: 171.19 g/mol
Inhalation: Remove person to fresh air, keep at rest and comfortable, seek medical attention if symptoms persist or worsen
Skin Contact: Remove contaminated clothing, wash skin immediately with soap and plenty of water for at least 15 minutes, medical assessment recommended if irritation occurs
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if present and easy to do, continue flushing, obtain medical attention right away
Ingestion: Rinse mouth, do not induce vomiting, seek medical advice immediately, provide information on material ingested
Most Important Symptoms: Redness, pain, irritation at points of contact; possible shortness of breath or headache if inhaled
Immediate Medical Attention: Provide detailed information about substance exposure to healthcare personnel
Suitable Extinguishing Media: Use dry chemical, CO2, alcohol-resistant foam, or water spray
Unsuitable Media: Avoid direct water jet as it may scatter contents and spread fire
Specific Hazards: Combustion releases carbon oxides, nitrogen oxides, toxic fumes
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, chemical protective clothing
Firefighting Procedures: Move containers away from fire area if it can be done safely, cool with water spray
Advice: Prevent runoff from entering drains, waterways, or soil; evacuate area if fumes become overwhelming
Personal Precautions: Use appropriate PPE including gloves, goggles, lab coats, ensure adequate ventilation
Environmental Precautions: Prevent spillage from reaching soil, drains, or waterways as chemical may harm aquatic and terrestrial life
Methods for Cleanup: Absorb material with inert absorbent (sand, vermiculite), collect in suitable closed containers for disposal, ventilate area, clean contaminated surface with soap and water
Emergency Procedures: Restrict access to the area until complete cleanup, alert others to potential danger, dispose debris as chemical waste
Safe Handling Procedures: Minimize dust generation and accumulation by working in a fume hood, avoid direct skin and eye contact, practice good hygiene—wash hands and exposed skin after use
Storage Conditions: Store in tightly closed original container, place in cool, dry, and well-ventilated area away from sources of ignition and strong oxidizers
Incompatibilities: Keep away from acids, strong bases, oxidizing agents
Specific Storage Requirements: Secure in designated chemical storage area suitable for toxic, flammable materials, label containers clearly
Storage Temperatures: Suggested ambient temperature, avoid freezing or excessive heat
Exposure Limit Values: Not established for Ethyl 4-Oxopiperidine-1-Carboxylate; follow general industrial hygiene recommendations
Engineering Controls: Use local exhaust ventilation, fume hood, or equivalent to reduce airborne exposures
Personal Protective Equipment: Protective nitrile gloves, safety goggles, lab coat
Respiratory Protection: Use NIOSH-approved respirator if dust or aerosol present in high concentrations
Hand Protection: Chemical-resistant gloves to limit direct exposure
Eye/Face Protection: Safety glasses or goggles with side shields
Other Controls: Do not eat, drink, or smoke during handling, follow workplace chemical hygiene plans, routine clean-up of surfaces and tools
Appearance: White to off-white crystalline powder
Odor: Mild, characteristic
Melting Point: 47-52°C
Boiling Point: 241-244°C at atmospheric pressure
Solubility: Slightly soluble in water, freely soluble in most organic solvents (ethanol, dichloromethane)
Vapor Pressure: Negligible at room temperature
Density: 1.15-1.22 g/cm³
pH: Neutral to slightly acidic in aqueous solution
Viscosity: Not applicable for solids
Flash Point: Estimated above 90°C
Molecular Weight: 171.19 g/mol
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Non-reactive with common materials at room temperature
Incompatible Materials: Oxidizing agents, strong acids, bases; may react with strong reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides formed on combustion or thermal decomposition
Hazardous Polymerization: Will not occur under normal conditions
Conditions to Avoid: Overheating, exposure to light or moisture, contact with incompatible chemicals
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat) data not widely published, estimated moderate toxicity; acute effects possible at above working concentrations
Skin Corrosion/Irritation: Causes skin irritation, may cause redness, pain, or dryness
Eye Damage/Irritation: Causes significant eye irritation
Sensitization: Not reported to cause sensitization based on available data
Chronic Effects: No data available for long-term exposure, exercise caution and use recommended protective equipment
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No classification as carcinogen or mutagen under current chemical safety standards
Other Information: Symptoms include headache, dizziness, or respiratory irritation if handled improperly
Ecotoxicity: May be harmful to aquatic organisms; avoid release to environment
Persistence and Degradability: Expected to biodegrade over time, but persistence in poorly ventilated or low-bacteria environments possible
Bioaccumulative Potential: Not expected to bioaccumulate significantly due to moderate solubility and low partition coefficient
Mobility in Soil: Moderate, based on chemical structure; possible leaching to groundwater if spilled in bulk
Other Adverse Effects: No known significant effects or critical hazards; responsible disposal protects ecosystems
Waste Treatment Methods: Dispose of contents and container in accordance with all local, regional, national, international regulations
Contaminated Packaging: Triple-rinse containers, treat as chemical waste
Special Precautions: Do not pour into drains, surface water, or soil; professional hazardous waste disposal services recommended
Recycling/Recovery: Not suitable for recycling due to contamination hazards
Small Spills: Absorb with inert material, transfer to a chemical waste drum
UN Number: Not assigned, not listed as a hazardous material under major transportation regulations
Proper Shipping Name: Chemical substance, not otherwise specified
Transport Hazard Class: Not classified as hazardous for road (ADR/RID), rail, sea (IMDG), air (IATA)
Packing Group: Not assigned
Marine Pollutant: Not considered a marine pollutant in packaged form
Special Precautions for Transport: Secure tightly, keep dry, avoid stacking heavy loads on container; label to indicate chemical identity during transit
Safety, Health, and Environmental Regulations: Not specifically listed on major chemical regulatory inventories as restricted or controlled
US Federal Regulations: Not classified under SARA Title III Sections 302/304/313, not a CERCLA hazardous substance
EU Regulations: Not registered under REACH for commercial volumes; check national requirements
Other Regulations: Always comply with local, workplace, or institutional chemical handling rules
Labelling: Must display hazard statements, pictograms, supplier information, and traceability on containers
Worker Protection: Training in safe handling recommended, chemical hygiene plan on site
Recordkeeping: Maintain inventory and exposure records where required by law
