Material Safety Data Sheet for Ethyl 2-Oximino-2-(2-Aminothiazole)-4-Acetate

Identification

Product Name: Ethyl 2-Oximino-2-(2-Aminothiazole)-4-Acetate
Chemical Family: Thiazole derivatives
Product Code: Provided by manufacturer
CAS Number: Manufacturer assigned
Recommended Use: Laboratory research or intermediate synthesis
Supplier Details: Name, address, phone number, emergency contact from supplier
Synonyms: Provided based on known literature
Emergency Phone Number: Listed by supplier for incidents

Hazard Identification

Classification: Acute oral toxicant (Category 4), skin sensitizer (Category 1B), possible eye irritant
Label Elements: Exclamation mark pictogram
Signal Word: Warning
Hazard Statements: Harmful if swallowed, may cause skin or eye irritation, potential respiratory irritation
Precautionary Statements: Avoid breathing dust, prevent skin and eye contact, use personal protective equipment
Unusual Hazards: May cause allergic skin reaction.
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Nausea, gastrointestinal discomfort, redness, itchiness, shortness of breath if inhaled
Target Organs: Not fully determined—avoid repeated exposure

Composition / Information on Ingredients

Chemical Name: Ethyl 2-Oximino-2-(2-Aminothiazole)-4-Acetate
Synonyms: Confirm from product information
Concentration: Pure or as indicated on product packaging
CAS Number: Provided by supplier or through chemical registry
Impurities/Additives: Minor based on batch, unknown impurities possible in trace
Other Components: None typically listed for pure compound; consult supplier’s specifications

First Aid Measures

Inhalation: Move affected person to fresh air, keep at rest, seek medical attention if symptoms persist, avoid direct exposure during aid
Skin Contact: Remove contaminated clothing, wash with plenty of soap and water, monitor for rash or irritation
Eye Contact: Rinse cautiously under running water for several minutes, remove contact lenses after initial rinse, consult medical staff if irritation persists
Ingestion: Rinse mouth with water immediately, do not induce vomiting, seek medical advice promptly
Most Important Symptoms: Irritation, abdominal discomfort, redness, shortness of breath
Immediate Attention: Encourage medical evaluation after any significant exposure
Other Notes: Provide safety data and product label to healthcare provider

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide—depends on fire location
Unsuitable Extinguishing Methods: Strong water jet may cause chemical spread
Special Hazards Arising: In combustion may release toxic gases such as nitrogen oxides, sulfur oxides, carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, chemical-resistant suit if large fire
Additional Measures: Keep containers cool, evacuate non-emergency personnel
Explosion Risks: No direct evidence, but exercise caution in dusty conditions
Advice for Firefighters: Stay upwind, avoid inhalation of combustion gases

Accidental Release Measures

Personal Precautions: Wear appropriate protective clothing, use gloves, avoid dust and vapors, ventilate area
Environmental Precautions: Prevent release to sewers or surface water, contain to avoid environmental contamination
Clean-Up Methods: Scoop up carefully, collect residue using non-sparking tools, place in approved container for waste, wash spill area with copious water
Decontamination: Use detergent and water for final cleaning
Emergency Procedures: Isolate hazard area, restrict unnecessary entry, report significant release as required to authorities

Handling and Storage

Safe Handling Advice: Use only in well-ventilated spaces, avoid contact with skin and eyes, prevent dust buildup
Hygiene Measures: Wash hands thoroughly after handling, remove contaminated clothing immediately
Conditions for Safe Storage: Keep container tightly closed, protect from moisture and strong oxidizers, store away from incompatible substances
Storage Temperature: Room temperature or as specified on supplier label
Segregation Requirements: Store apart from strong acids, bases, oxidizers
Packaging Material: Glass or high-density polyethylene preferred, must resist chemical degradation
Other Storage Notes: Label containers clearly, prevent unauthorized access

Exposure Controls and Personal Protection

Engineering Controls: Efficient laboratory fume hood, local exhaust ventilation, avoid open handling in confined spaces
Exposure Limits: No established occupational exposure limits; minimize exposure as good practice
Eye/Face Protection: Chemical splash-proof safety goggles or face shield
Skin Protection: Gloves rated for chemical resistance—nitrile or neoprene, laboratory coat
Respiratory Protection: Dust mask (N95 or equivalent) for uncontrolled aerosols or powder, full-face respirator for large spills
Body Protection: Chemical-resistant apron when risk of splashing
General Safety Measures: No eating or drinking in work area, keep emergency shower and eyewash station accessible

Physical and Chemical Properties

Appearance: Pale yellow to light brown powder (based on typical thiazole derivatives)
Odor: Mild, characteristic sulfur/nitrogen odor
Odor Threshold: Not determined due to limited data
pH: Not readily soluble enough for standard measurement
Melting Point/Freezing Point: Approximately 120-140°C, consult product-specific data
Boiling Point: Not practically measured due to decomposition
Flash Point: Data not available, assumed not highly flammable
Evaporation Rate: Not applicable
Flammability: Not classified as highly flammable
Vapor Pressure: Expected low at room temperature
Vapor Density: Data not available
Relative Density: Estimate: 1.2–1.3 g/cm3
Solubility: Slightly soluble in water
Partition Coefficient (n-octanol/water): Data not available
Auto-ignition Temperature: Not established
Decomposition Temperature: Expected above 140°C
Viscosity: Not applicable; presents as solid

Stability and Reactivity

Chemical Stability: Stable under recommended storage, avoid heat exposure
Possible Hazardous Reactions: No hazardous polymerization anticipated
Conditions to Avoid: High temperatures, direct sunlight, strong oxidizing agents
Incompatible Materials: Strong acids, bases, oxidizers, reducing agents
Hazardous Decomposition Products: May emit toxic gases including nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Stability Guidance: Avoid contact with incompatible materials, do not allow to dry out entirely if supplied as moist solid

Toxicological Information

Likely Routes of Exposure: Skin, eyes, inhalation, accidental ingestion
Acute Toxicity: Harmful if swallowed; estimated LD50 oral (rat) 300–2000 mg/kg (heterocyclic compounds similar range)
Skin Corrosion/Irritation: Possible mild to moderate irritant
Serious Eye Damage/Irritation: Potential irritant
Respiratory Sensitizer: Not classified, avoid generating particulates
Skin Sensitizer: Sensitization possible, especially with repeated contact
Germ Cell Mutagenicity: No data; structure does not suggest high risk, but avoid unnecessary exposure
Carcinogenicity: No IARC/NTP/OSHA indicators for this compound
Reproductive Toxicity: No specific data, caution advised
Specific Organ Toxicity – Single Exposure: May cause respiratory or digestive discomfort
Specific Organ Toxicity – Repeated Exposure: Not determined
Aspiration Hazard: Not anticipated for solid unless inhaled as powder
Delayed/Immediate Effects: Allergic reactions, redness, itching possible with skin contact

Ecological Information

Ecotoxicity: No measured data on aquatic or terrestrial life; structurally, heterocyclic organics often present risk to fish and invertebrates
Persistence and Degradability: Thiazole derivatives degrade slowly; may persist in environment
Bioaccumulation Potential: Moderate potential due to chemical stability and aromaticity
Mobility in Soil: Expected low mobility, binds to organic matter
Other Adverse Effects: Harm to aquatic organisms cannot be excluded, do not release into drains
Avoid Release Guidelines: Dispose of as hazardous waste, keep out of water course

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, national regulations, incinerate with flue gas scrubbing preferred
Safe Handling for Disposal: Use chemical-resistant gloves and eye protection, avoid dust production
Container Disposal: Triple rinse and puncture, deliver to licensed chemical waste facility
Methods for Contaminated Packaging: Treat as hazardous waste
Local Disposal Guidelines: Follow jurisdiction requirements, consult environmental authorities
Disposal Precautions: Label waste containers clearly, store securely until disposal

Transport Information

UN Number: Not classified for road/rail/sea in nondangerous quantities, check current guidelines
UN Proper Shipping Name: Consult shipping authority – usually “Laboratory Chemicals, N.O.S.”
Transport Hazard Class(es): No specific DG class unless supplied in large quantities
Packing Group: Based on supplier determination
Marine Pollutant: Not specifically listed, treat as potentially hazardous
Special Transport Precautions: Secure packaging, avoid moisture, keep separated from foodstuffs
Environmental Hazards During Transit: Do not allow to enter environment, contain spills
Transport Documentation: Ensure safety datasheet travels with shipment

Regulatory Information

Safety, Health and Environmental Regulations: Not listed on major inventories (TSCA, REACH) unless imported in bulk, check local regulations for laboratory chemical use
OSHA Status: Handle as hazardous chemical under laboratory standards
SARA Title III: Not a listed hazardous substance; follow general chemical storage best practices
WHMIS (Canada): Not classified—general laboratory chemical treatment; GHS pictogram applies
State/Provincial Guidelines: Refer to local environmental protection lists
Other National Inventory Status: Confirm with supplier for market-specific requirements
Label Elements Mandated: Signal word, hazard pictograms, supplier details, hazard and precaution statements
Other Regulatory Notes: Always consult up-to-date regional chemical databases before large-scale work