Product Name: Methyl 2-Aminothiazole-4-Carboxylate
Chemical Formula: C5H6N2O2S
Synonyms: Methyl thiazole-4-carboxylate-2-amine
CAS Number: 23522-60-1
Recommended Use: Intermediate in chemical synthesis and pharmaceuticals manufacturing
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Relevant Identified Uses: Laboratory reagent, research applications
Classification: Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: Causes skin irritation, can cause moderate eye irritation, may cause respiratory tract irritation
Precautionary Statements: Wear protective gloves and eye protection, avoid breathing dust, wash hands thoroughly after handling
Health Hazards: Prolonged or repeated skin contact may lead to dermatitis, exposure to dust or vapors may aggravate pre-existing respiratory conditions
Environmental Risks: Not expected to be hazardous to the environment in small quantities, but large releases can affect aquatic organisms if not contained
Chemical Name: Methyl 2-Aminothiazole-4-Carboxylate
CAS Number: 23522-60-1
Concentration: 98% or higher
Impurities: Typically contains less than 2% unidentified trace organic materials
Inhalation: Move to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms develop
Skin Contact: Wash with soap and water, remove contaminated clothing, get medical help if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, keep rinsing, seek medical care if causes pain or redness
Ingestion: Rinse mouth, avoid vomiting, do not give anything by mouth if victim is unconscious, immediate medical attention is important for large quantities
Most Important Symptoms: Redness, itching, respiratory discomfort in poorly ventilated spaces
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Specific Hazards: Product can emit nitrogen oxides, sulfur oxides, and carbon oxides in high-heat fire scenarios
Special Equipment: Firefighters should use self-contained breathing apparatus and full protective gear to avoid smoke inhalation
Advice: Cool exposed containers with water spray to minimize risk of rupture, evacuate area if fire cannot be controlled quickly
Personal Precautions: Wear gloves, goggles, use a dust mask or respirator for significant spills
Environmental Precautions: Avoid allowing powder to enter drains, waterways, or soil
Spill Cleanup: Scoop up using non-sparking tools, place in chemical waste container, ventilate area thoroughly, dispose of according to local regulations
Decontamination: Wash impacted area with detergent, rinse carefully, collect wash water for proper disposal
Safe Handling: Use only outdoors or in a well-ventilated area, wear appropriate personal protection, avoid creating dust clouds
Hygiene Measures: Wash hands after handling, keep work clothes separate
Storage Conditions: Store in a tightly sealed container in a cool, dry, well-ventilated place, keep away from incompatible materials like strong oxidizers or acids
Incompatible Materials: Avoid strong oxidizers, strong acids, and bases to reduce risk of hazardous reactions
Engineering Controls: Handle in a chemical fume hood, ensure adequate ventilation at workstations
Eye Protection: Use safety goggles or face shield
Skin Protection: Wear lab coat, chemical-resistant gloves, avoid contact with exposed skin
Respiratory Protection: Use approved respirator for dust or powder exposure, especially in poorly ventilated spaces
Environmental Controls: Use systems to prevent dust release, contain washwaters from cleaning up spillage
Appearance: Off-white to pale yellow crystalline solid
Odor: Slight, characteristic chemical smell
Boiling Point: Data not available, decomposes before boiling
Melting Point: Approximately 120–125°C
Solubility: Slightly soluble in water, soluble in organic solvents like ethanol and DMSO
Vapor Pressure: Negligible under ambient conditions
pH: Not applicable in solid state
Density: Estimated at 1.5 g/cm³ (literature values can vary)
Flash Point: Not readily flammable
Partition Coefficient (Log Kow): Not established
Chemical Stability: Stable under normal handling and storage conditions
Reactivity: No dangerous reactions under standard use, avoid strong oxidizers
Conditions to Avoid: Moisture, heat above normal storage levels, high humidity
Decomposition Products: Nitrogen oxides, carbon dioxide, carbon monoxide, sulfur compounds can be released upon decomposition
Likely Routes of Exposure: Inhalation, skin and eye contact, incidental ingestion
Acute Toxicity: No specific data for LD50, but expected to have low acute toxicity based on structure
Chronic Effects: Long-term exposure could promote skin sensitization or dermatitis, no carcinogenicity or developmental toxicity data available
Symptoms: Skin redness, burning sensation, mild respiratory irritation if dust is inhaled
Eye Damage: Causes moderate eye irritation, avoid direct contact
Ecotoxicity: Data not fully established for this compound, high amounts could be harmful to aquatic organisms
Persistence and Degradability: Compound expected to be partially biodegradable, but details vary with local soil and water chemistry
Bioaccumulation Potential: Seems low based on molecular size and solubility
Mobility in Soil: Low volatility, limited mobility in soil
Other Effects: Large spills may temporarily contaminate water or soil and affect invertebrates or algae
Waste Treatment Methods: Collect product and send for disposal at a licensed hazardous waste facility
Contaminated Packaging: Rinse containers thoroughly, dispose of as hazardous waste
Sewage Disposal: Do not pour into drains or watercourses
Special Instructions: Work with local authorities to manage waste according to environmental standards, avoid incinerating with regular waste
UN Number: Not allocated for this product
Proper Shipping Name: Not regulated by transport regulations for most countries
Hazard Class: Not classified as a hazardous material for shipping
Packing Group: Not assigned
Transport Precautions: Store transport containers upright and away from sources of physical damage, avoid extreme temperatures during shipment
Special Provisions: Double-bagging and padding may help contain product if primary packaging ruptures
OSHA Status: Not specifically listed as hazardous under OSHA Hazard Communication Standard
TSCA Status: Listed or approved for use subject to reporting requirements
REACH Status (EU): Registration may be required above 1 tonne per year
Other National Inventories: Review local chemical regulations in your country for specific restrictions or labeling requirements
Labeling Requirements: Use hazard pictograms and precautionary statements per GHS guidelines if available
Additional Information: Check safety rules regularly for updates as data evolves and regulations change
